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BACKGROUND: Anastomotic leakage after anterior resection for rectal cancer is more common after total mesorectal excision compared to partial mesorectal excision but might be mitigated by a defunctioning stoma. OBJECTIVE: The aim is to assess how anastomotic leakage is affected by type of mesorectal excision and defunctioning stoma use. DESIGN: This is a retrospective multicenter cohort study eval
Introduction: Food systems strongly influence both human and planetary health. Unhealthy diets aremajor risk factors for chronic disease and mortality, while food production contributes substantially togreenhouse gas emissions (GHGE), and other negative environmental impacts. Adopting moresustainable dietary patterns, such as the EAT-Lancet diet, has been proposed as part of the solution, butuncer
Background: Minimising time from injury to hospital admission is considered a key factor in trauma. Trauma care is often centralised to hospitals, which, because of their urban location, make treatment more accessible to patients in densely populated areas. If prehospital time increases with declining population density, an effect on mortality could hence be present. The primary aim of this study
Global water scarcity requires innovative treatment solutions. This presentation explores three membrane-based concepts advancing from idea to pilot scale: stormwater harvesting with micro-/ultrafiltration (MF/UF), direct membrane filtration (DMF) for wastewater treatment, and a hybrid forward osmosis (FO), membrane distillation (MD), and nanofiltration (NF) system for seawater desalination.The EU
Introduction: Target volume delineation is crucial in breast cancer radiotherapy planning but involves significant interobserver variability. Deep learning (DL) models may reduce this variability, saving time and costs. However, current DL-models do not consider clinical data, such as tumor location and patient comorbidity, to adjust the target and reduce dose to organs at risk (OAR). This study c
Background: Influenza ranges from a mild and self-limiting infection to a life-threatening disease with high mortality despite intensive care. Conclusive data on the association between influenza type/subtype and mortality among adults treated at intensive care units (ICU) is lacking. Objectives: To investigate the mortality in adults admitted to ICU with laboratory-confirmed influenza during thre
Background Low-grade systemic inflammation is linked to abnormal spirometry. Impulse oscillometry (IOS) is sensitive in detecting peripheral airway dysfunction, but inflammation in relation to IOS is poorly studied. The objectives of the present study were to analyse associations between C-reactive protein (CRP), blood eosinophils (B-Eos), blood neutrophils (B-Neu), blood lymphocytes (B-Lym), bloo
Ledarskap har beskrivits som ett undflyende fenomen – en (positiv) lösning som kan kopplas till nästintill alla problem, men är svårt att fånga när det händer. Karisma, transformation och extraordinärisering utgör synsätt på ledarskap där särskilda individer tillskrivs extraordinära egenskaper, men de har inte fångat hur detta görs i vardagliga interaktioner. Ledarskap som praktik och ledarskap i Leadership has been described as a disappearing phenomenon – a (positive) solution that can be attached to almost any problem, yet it is difficult to capture as it happens. Charisma, transformation, and extra-ordinarization are perspectives on leadership where certain individuals are ascribed extraordinary qualities, but this is not captured analytically in everyday interactions. However, Leadersh
Background: Mental health professionals often differ in their explanatory models of mental distress, which may influence their attitudes toward individuals experiencing such conditions. Stigmatizing attitudes among providers can adversely affect therapeutic relationships, service quality, and recovery outcomes. Aims: This study investigates the attributional frameworks—biological, cognitive-behavi
Background: Chronic subdural hematoma (CSDH) is a rapidly growing neurosurgical condition, driven primarily by an aging population and the increasing use of antithrombotic medications. Approximately 25% of CSDH patients are on anticoagulants due to atrial fibrillation (AF). The postoperative management of these patients presents a significant clinical challenge, as clinicians must balance the risk
Inappropriate bricklaying techniques can result in extruded mortar joints, which may partially fill the air gaps within brick veneer timber frame walls. This leads to an unintended connection or “bridge” between the brick masonry cladding and its adjacent layer (such as insulation or weather-resistant barriers). This bridging effect compromises the capillary break function of the air gap, allowing
BACKGROUND: Recent research using a data-driven cluster approach has identified five discordant subclassifying body mass index (BMI) subgroups, characterized by cardiometabolic biomarkers deviated from those predicted by BMI.OBJECTIVE: This study aimed to investigate the associations of these subgroups with risks of metabolic dysfunction-associated steatotic liver disease (MASLD) and liver-related
BACKGROUND: Peptic gastroduodenal stenosis is a rare but disabling condition causing gastric outlet obstruction. This study aimed to evaluate endoscopic balloon dilation in terms of treatment effectiveness, durability, and identify potential early predictors of unsatisfactory outcomes.METHODS: We conducted a retrospective cohort study of patients who underwent endoscopic balloon dilation for sympt
While Generative Artificial Intelligence (GAI), particularly tools powered by Large Language Models (LLMs), offer benefits in teaching and learning, they also raise critical concerns about academic integrity, fairness in examinations d ue to their potential for generating educational content. This evolving landscape requires higher education institutions to rethink their assessment models, e
Background Bariatric metabolic surgery (Roux-en-Y gastric bypass [RYGB] and sleeve gastrectomy [SG]) effectively treats obesity and type 2 diabetes; however, weight loss varies, necessitating predictive factors. Methods We analysed 12- and 24-month weight loss data from 811 patients (RYGB or SG). Factor Analysis of Mixed Data and neural network (NN) modelling identified distinct patient phenotypes
BACKGROUND AND AIMS: Atherosclerotic plaques are the leading cause of cardiovascular events. Single-cell approaches have identified diverse human plaque cell phenotypes but their spatial distribution and interactions remain unclear. Here, intercellular communication patterns in human plaque microenvironments were mapped to reveal novel targets to prevent atherosclerotic events.METHODS: Spatial tra
Purpose Gangliogliomas are highly epileptogenic tumors that are common in epilepsy surgery. The main aim of this study was to investigate whether the outcome of Anti-seizure medication (ASM) withdrawal differed between patients undergoing ganglioglioma surgery in an epilepsy surgery program compared with those who underwent surgery in other surgical programs. We also investigated which factors inf
