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Mental health problems affect the patients and their families, who may also need therapeutic interventions. Mindfulness interventions have shown beneficial health effects for clinical and healthy populations. A web-based mindfulness intervention was tailored to address families' needs of support and tested in a pilot intervention study. The aim of this study was to explore the participants' experi

Ecosystem-based approaches for climate change adaptation are promoted at international, national, and local levels by both scholars and practitioners. However, local planning practices that support these approaches are scattered, and measures are neither systematically implemented nor comprehensively reviewed. Against this background, this paper advances the operationalization of ecosystem-based a

Background: General practice systems in the Nordic countries share certain common features. The sector is based on the Nordic model of a tax-financed supply of services with a political objective of equal access for all. The countries also share the challenges of increased political expectations to deliver primary prevention and increased workload as patients from hospital care are discharged earl

Background - Cardiovascular risk factors tend to aggregate. The biological and predictive value of this aggregation is questioned and genetics could shed light on this debate. Our aims were to reappraise the impact of risk factor confluence on ischemic heart disease (IHD) risk by testing whether genetic risk scores (GRSs) associated with these factors interact on an additive or multiplicative scal

Aims/hypothesis: Insufficient insulin release and hyperglucagonaemia are culprits in type 2 diabetes. Cocaine- and amphetamine-regulated transcript (CART, encoded by Cartpt) affects islet hormone secretion and beta cell survival in vitro in rats, and Cart−/− mice have diminished insulin secretion. We aimed to test if CART is differentially regulated in human type 2 diabetic islets and if CART affe

Herein, we examined insulin resistance (IR), insulin sensitivity (IS), beta cell activity, and glucose metabolism in subjects with antisocial personality disorder (ASPD), and whether the serotonin 2B (5-HT2B) receptor and testosterone have a role in energy metabolism. A cohort of subjects belonging to a founder population that included 98 ASPD males, aged 25–30, was divided into groups based on th

Background: Cadmium is a toxic metal with multiple adverse health effects, including risk of cardiovascular disease (CVD). The mechanistic link between cadmium and CVD is unclear. Our aim was to examine the associations between blood cadmium (B-Cd) and 88 potential protein biomarkers of CVD. Methods: B-Cd and 88 plasma proteins were measured in a community-based prospective cohort, the Malmö Diet

Background:Nurses and physicians in nephrology settings provide care for patients with end-stage kidney disease receiving hemodialysis treatment along a complex illness trajectory.Aim:The aim was to explore physicians’ and nurses’ perspectives on the trajectories toward the end of life involving decisions regarding hemodialysis withdrawal for patients with end-stage kidney disease.Research design

BACKGROUND: Widespread pain is a common comorbidity in several chronic diseases and is suspected to be caused by the underlying disease that has provoked a state of central sensitization. However, this argument is currently limited by evidence that has not sufficiently captured the temporal nature of the relationship between diagnosis of the underlying disease and onset of widespread pain. The aim

This paper discusses the existence and scope of the morality exception from patentability, in Article 53 (a) of the European Patent Convention. The analysis will look into the history of the provision, debate its rational and interpretation by reference to three examples of technology areas: stem cell research; gene editing and AI/big data analytics.Bioscience innovation has always generated heate

On-going debates within feminist and social science research are increasingly highlighting the need for reflexive scholarship (particularly within qualitative research) – both in terms of considering the emotionality of the research process (Brownlie 2014, Burkitt 2012, Doucet 2008, Holland 2005, Mauthner and Doucet 2003) and in terms of applying an intersectional lens and discussing researchers’

Aims/hypothesis. Our aims were to investigate the concentrations and prevalence of autoantibodies against the Mr 65.000 isoform of glutamate decarboxylase (GAD65) and the tyrosine phosphatase-like protein (IA-2) in adults and to test the hypothesis that GAD65 and IA-2 autoantibodies in a regional population are related to abnormal oral glucose tolerance. Methods. We analysed serum from 2157 Swedis

Aim: It has been claimed that supraspinal structures are necessary forthe depression of nocifensive behaviour elicited by acupuncture or acupuncturelike (AL) stimulation. However, nocifensive reflexes in the spinal catwere inhibited for long periods by a mechanism releasing opieids on AL conditioning stimulation of groups II-III muscle afferents (Sj~lund and Eriksson, Neurosci.Lett. S3:264:1979).