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In English and in Scandinavian, presentational expletive constructions with clause-final subjects can be derived by moving the subject to a Spec position in the C-domain, and then raising the remainder of the clause across the subject to an even higher position. The discourse properties of the clause-final subjects then follow without further stipulations. Moreover, the view that the clause-final
Ca2+-sensor proteins are generally implicated in insulin release through SNARE interactions. Here, secretagogin, whose expression in human pancreatic islets correlates with their insulin content and the incidence of type 2 diabetes, is shown to orchestrate an unexpectedly distinct mechanism. Single-cell RNA-seq reveals retained expression of the TRP family members in β-cells from diabetic donors.
The driving force behind the current global type 2 diabetes epidemic is insulin resistance in overweight and obese individuals. Dietary factors, physical inactivity, and sedentary behaviors are the major modifiable risk factors for obesity. Nevertheless, many overweight/obese people do not develop diabetes and lifestyle interventions focused on weight loss and diabetes prevention are often ineffec
Mass-flowering crops lead to spatial redistributions of pollinators and to transient shortages within nearby semi-natural grasslands, but the impacts on plant-pollinator interactions remain largely unexplored. Here, we characterised which pollinator species are attracted by oilseed rape and how this affected the structure of plant-pollinator networks in nearby grasslands. We surveyed 177 networks
The paper investigates possible effects of cross-linguistic variation on measures of syntactic complexity in 60 texts from learners of L2 English, L3 French and L4 Italian at CEFR level A and CEFR level B. A previous study by Gyllstad et al. (2014) showed significant differences between proficiency levels for two length measures of complexity in English and French, but not in Italian. In this pape
The challenge of multi-use forestry is to fulfil a range of economic, ecologic and social goals in a sustainable way, accounting for synergies and trade-offs among the ecosystem services provided. Climate changes add to the complexity via effects on forest ecosystem processes, such as primary production and respiration, and also by adding a new goal on the agenda: the role of forests in climate mi
The localization of glucokinase in pancreatic beta-cell nuclei is a controversial issue. Although previous reports suggest such a localization, the mechanism for its import has so far not been identified. Using immunofluorescence, subcellular fractionation and mass spectrometry, we present evidence in support of glucokinase localization in beta-cell nuclei of human and mouse pancreatic sections, a
This article investigates the cross-linguistic comparability of the newly developed lexical assessment tool Cross-linguistic Lexical Tasks (LITMUS-CLT). LITMUS-CLT is a part the Language Impairment Testing in Multilingual Settings (LITMUS) battery (Armon-Lotem, de Jong & Meir, 2015). Here we analyse results on receptive and expressive word knowledge tasks for nouns and verbs across 17 language
The language of newspapers in the public sphere has a crucial impact on how the public perceives and participates in society. It can serve to encourage or counteract active and informed citizens; in fact, it is a crucial element in democratisation processes. The purposes of the present study are to elucidate what means of persuasion are used to support theses on politics in newspaper discours
The protection of trade secrets in Portugal and Spain has been derived from general legal principles (of Civil Law, Penal Law and Unfair Marketing Law). This chapter on implementation of the Trade Secrets Directive (TS Directive) in Portugal and Spain presents the traditional views and positions and the implementation of the TS Directive into the respective national legal orders.In Portugal, imple
This paper is about, from a North and South different perspective, how the international focus of sustainable construction issues has changed over the past ten years. It is a review from four different international and regional sustainable building conferences between 1998 and 2007. The paper is mostly based of the first author's notes from the conferences, especially from the plenary sessions an
Talk in safety-critical activities displays features that distinguish it from both ordinary conversations as well as from other institutional talk, but it also shares some features with these. Formality and informality are both interactionally accomplished phenomena, although shaped through different sources. Safety rules and pre-printed forms constitute two sources of formalization, dictating how
