A person's lipid profile is influenced by genetic variants and alcohol consumption, but the contribution of interactions between these exposures has not been studied. We therefore incorporated gene-alcohol interactions into a multiancestry genome-wide association study of levels of high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and triglycerides. We included 45 studies

In this paper, we explore how the notion of participation informs policy documents in a public library context. Today, library users to a large extent are expected to manage on their own and society calls for self-governing, active subjects who are willing to participate. To explore the notion of participation we utilize the concept of problematization and conduct a text analysis of policy documenThis article explores how the notion of participation informs policy documents in a public library context. Library users are expected to manage on their own, to a large extent, as society calls for self-governing, active subjects who are willing to participate. To explore this notion of participation, we utilize the concept of problematization and analyze policy documents regarding the public lib

This paper discusses topicality in Icelandic grammar as realized in severalphenomena: referential third person pro drop in Old Icelandic, diverse typesof topic drop in Old and Modern Icelandic, and Narrative Inversion (declarativeVS clauses), also in both Old and Modern Icelandic. These phenomena all involveaboutness topics, given topics or both, thus showing that distinct types of topicality are This paper discusses topicality in Icelandic grammar as realized in several phenomena: referential third person pro drop in Old Icelandic, diverse types of topic drop in Old and Modern Icelandic, and Narrative Inversion (declarative VS clauses), also in both Old and Modern Icelandic. These phenomena all involve aboutness topics, given topics or both, thus showing that distinct types of topicality

The recent global success story of Nordic noir, that encompasses products from film and television as well as literature, is often attributed to the great popularity of its places and characters. Many of the protagonists of some of the most popular TV-shows, for instance, are described as more in depth-characters than many of their European and American counterparts. Notable examples are Kurt Wall

Dipeptidyl peptidase 4 (DPP-4) inhibitors are now being clinically utilized as glucose-lowering medications for the treatment of type 2 diabetes. Their widespread use and effective glucose-lowering properties have led to great interest in the mechanism of action of this class of drug. Although it has been well accepted that DPP-4 inhibitors lower glucose in part by increasing postprandial insulin

Denna artikel diskuterar en ny form av snabbt expanderande praktiker från tidigt 2000-tal och som erbjuds av privata företag eller entreprenörer (lekmannaterapeuter). I fokus står självförverkligande och helande. Jag har med hjälp av verktyg från Ritual Studies valt att analysera dessa praktiker som en form av individ-centrerade riter som designas för att lindra smärta och lågt självförtroende för

Recently, there has been a rise of contributions in innovation and economic geography studies on how firms from specific industries and regional innovation systems (RISs) rely on international networks to innovate. So far, the focus has been on single cases, firms located in well-known RISs and international linkages, without really distinguishing those with geographically close partners from thos

The catastrophic disruption of the L chondrite parent body in the asteroid belt c. 470 Ma initiated a prolonged meteorite bombardment of Earth that started in the Ordovician and continues today. Abundant L chondrite meteorites in Middle Ordovician strata have been interpreted to be the consequence of the asteroid breakup event. Here we report a zircon U-Pb date of 467.50±0.28 Ma from a distinct be

We present and test a model of the accumulation of plant competences. Fundamentally, the cumulative model consists of three building blocks: production competences, supply chain competences, and development competences, which are added successively. First, the basic production competence bundle comprises manufacturing, technical maintenance, and process development. Second, supply chain competence

For many years, a connection between circadian clocks and cancer has been postulated. Here we describe an unexpected function for the circadian repressor CRY2 as a component of an FBXL3-containing E3 ligase that recruits T58-phosphorylated c-MYC for ubiquitylation. c-MYC is a critical regulator of cell proliferation; T58 is central in a phosphodegron long recognized as a hotspot for mutation in ca

In this paper, we investigate the annotation projection of semantic units in a practical setting. Previous approaches have focused on using parallel corpora for semantic transfer. We evaluate an alternative approach using loosely parallel corpora that does not require the corpora to be exact translations of each other. We developed a method that transfers semantic annotations from one language to