The two monoamines serotonin and melatonin have recently been highlighted as potent regulators of islet hormone secretion and overall glucose homeostasis in the body. In fact, dysregulated signaling of both amines are implicated in β-cell dysfunction and development of type 2 diabetes mellitus (T2DM). Serotonin is a key player in β-cell physiology and plays a role in expansion of β-cell mass. Mela

These days, talk of quantum technologies and the coming “quantum revolution” or “quantum leap” is hard to miss. There is a broad agreement that quantum technologies have a high probability of becoming the next disruptive technological development, and the way they should be regulated and the timing of such intervention are issues that are attracting increasing attention. An analysis of how these q

Paediatric prospective studies of coeliac disease with longitudinal collection of biological samples and clinical data offer a unique perspective on disease risk. This Review highlights the information now available from international paediatric prospective studies on genetic and environmental risk factors for coeliac disease. In addition, recent omics studies have made it possible to study comple

This chapter aims at analysing the inter-organisational networks emerging from interlocking leaders among the most resourceful, national-level civil society organisations (CSOs) in four European countries. By comparing four different country contexts, we analyse differences in the characteristics of networks, find different mechanisms that seem to structure organisational links across the cases, a

Multiple language learning has been largely neglected in L2 motivation research. Recently, complexity principles have been used to model multilingual motivation. In this work, multilingual self-guides are conceptualised as emergent from interactions between the motivation systems of different languages. Motivational systems and their emergent properties are also influenced by the contexts in which

Learning a language is a long-term undertaking. In this endeavor, motivation is served by patterns of regulation that steer and control behavior. Regulation can be focused on possibilities and opportunities (an approach pattern), or the implications of failure (an avoidance pattern). Responding to calls for work with a focus on regulation (Papi et al., 2019), and with the aim of developing insight

Demotivation (Dörnyei & Ushioda, 2011) and non-participation (Norton, 2001) characterise negative responses to classroom practice of a generally chronic nature. In this article, focus is directed to negativity that emerges within the context of a particular language developing activity, and which can be understood as a situated response to the activity's demands. In conceptualizing negative re

Novel biomarkers are key to addressing the ongoing pandemic of type 2 diabetes mellitus. While new technologies have improved the potential of identifying such biomarkers, at the same time there is an increasing need for informed prioritization to ensure efficient downstream verification. We have built BALDR, an automated pipeline for biomarker comparison and prioritization in the context of diabe

During WWII, the botanist Hylander (1943, 1949) studied the floristic composition of lawns in 249 landscape gardens mostly in Sweden and concluded that they all harboured multiple, but largely the same, non-native species and genotypes that had most likely been introduced together by the sowing of some im- ported grass seed mix. As demonstrated by the later additions by, for example, Ohlsén (1947)

This paper revisits the glazed redware Scanian jug, brought to the fore by Kulturen archaeologist Anders W. Mårtensson in 1973. Characterized by its faceted base and distinct handle, the jug stands out from its contemporaries. This brief paper presents new chemical data for the Scanian jug, its most common rim forms and a discussion on its area of production. So far, no medieval ceramic production

We are now seeing the development of a new generation of synchrotron radiation sources, the seeded, short-wavelength Free Electron Lasers (FELs), which are capable of driving the radiation to even higher intensities, and with new capabilities such as longitudinal coherence and ultra-short pulses. The Workshop on High-harmonic Seeding for Present and Future Short Wavelength Free-Electron Lasers, ho

The key message is the importance of a systemic approach to handling water and energy together, both in design and in oper-ation. The paper demonstrates how renewable energy, solar photovoltaic (PV) and solar thermal, in combination with a small nutrient removal plant, provides a reliable solution for small-scale decentralized water recovery operations. The system is automated and can operate outs

In Scandinavia, the loss of members in established (or formerly established) churches, the rise of unaffiliated, and diverse migration led to a need for new approaches to historically Christian spaces. To create all-inclusive spaces, the idea of neutrality has been adopted. Among others, burials, and cemeteries, which are still mostly run by the national churches, have been affected by this effort

Mobile Stroke Units (MSUs) are specialized ambulances that can diagnose and treat stroke patients; hence, reducing the time to treatment for stroke patients. Optimal placement of MSUs in a geographic region enables to maximize access to treatment for stroke patients. We contribute a mathematical model to optimally place MSUs in a geographic region. The objective function of the model takes the tra