Polyglandular Autoimmune (PGA) syndrome type II in idiopathic Addison's disease: In a retrospective study of idiopathic Ad-dison's disease (median age at diagnosis 32.5 years, range 8-62; median observation time 17 years, range 0.5-41), 50% met the criteria for PGA syndrome type II. In PGA syndrome type II, 73% had ATD and 41% had IDDM. The full triad was present in 14%. The sequence of appearance

High levels of proenkephalin-A (pro-ENK) have been associated with decreased eGFR in an acute setting. Here, we examined whether pro-ENK levels predict CKD and decline of renal function in a prospective cohort of 2568 participants without CKD (eGFR>60 ml/min per 1.73 m2) at baseline. During a mean follow-up of 16.6 years, 31.7% of participants developed CKD. Participants with baseline pro-ENK leve

AbstractThis essay focuses on teachers' perspective on student engagement and aims to highlight the connection between student engagement, teaching and content matter. It investigates how teachers interpret the concept of student engagement and what consequences their interpretation have for themselves, their teaching and their students. It also examines how teachers perceive the relationship betw

Background: Patients with first-time myocardial infarction (MI) and diabetes mellitus (DM) constitute a vulnerable subgroup of cardiovascular (CV) patients for which secondary prevention is particularly important. We investigated if patients with versus without DM differ in attaining four main lifestyle-related cardiac rehabilitation (CR) targets, one-year post-MI. Methods: This national cohort st

Abstract: Cardiovascular diseases and diabetes mellitus are closely linked by sharing common risk factors, such as obesity, insulin resistance, hypertension and dyslipidaemia. These intermediate risk factors are affected by the joint effects of environment and genetics. Although a multitude of studies aimed to disentangle the effects of gene-environment interactions, many of the published gene-en

Although prior falls are a well-established predictor of future fracture, there is currently limited evidence regarding the specific value of falls history in fracture risk assessment relative to that of other clinical risk factors and bone mineral density (BMD) measurement. We therefore investigated, across the three Osteoporotic Fractures in Men (MrOS) Study cohorts, whether past falls predicted

BACKGROUND: Cardiac rehabilitation (CR) programs addressing risk factor management, educational interventions, and exercise contribute to reduce mortality after myocardial infarction (MI). However, the fulfillment of guideline-recommended CR targets is currently unsatisfactory. eHealth, i.e., the use of electronic communication for healthcare, including the use of mobile smartphone applications co

The red admiral (Vanessa atalanta) is a migratory butterfly that can be found in North America, North Africa, Europe and some parts of Asia. In Europe the main part of the population spend winter in the Mediterranean region and the following spring leave this area to breed further to the north. At least one new generation is then produced in the summer region before they return to the south again

Introduction Risk management in enterprises, organisations and companies has had a long and complicated history. During the eighties, and at least during the beginning of the nineties, the notion concerning risk management was that if an accident happened in an otherwise perfect system it was due to the human operator in some way being the cause of the error. The cause for the accidents was desc

A sustainable development of the built environment asks for changes in urban residents’ mobility patterns. The extensive use of the car contributes to sedentary lifestyle and negative environmental impact in many respects. Children living in urban areas are faced with limits of their independent use of the environment both in terms of travel and outdoor play. Many parents hold favourable attitudes

This paper examines how an industrial legacy leads to the formation of a distinct local culture and how the culture’s survival provides a context for the subsequent entrepreneurial activities in new local industries. The discussion about culture as a key driver of entrepreneurship and economic growth is well established in the academic debate. However, we know little about how culture is formed. T

It has been hypothesized that low frequency (1-5% minor allele frequency (MAF)) and rare ( 1000-fold more significant than the previous sentinel variant and not in close LD (six had MAF < 5%). Furthermore, conditional analysis revealed multiple independent signals (ranging from 1 to 5) in a third of the 98 lipid loci tested, including rare variants. Addition of our novel associations resulted in b

Like many other large cities, Stockholm is facing increased urbanization with densification of infrastructure as a result. At the same time, implementation of the Baltic Sea Action Plan and the EU Water Framework Directive is expected to result in more stringent effluent quality demands. The current situation gives rise to new challenges for the municipal wastewater treatment plants (WWTPs). This