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Season-dependent associations of circadian rhythm-regulating loci (CRY1, CRY2 and MTNR1B) and glucose homeostasis: the GLACIER Study.
The association of single nucleotide polymorphisms (SNPs) proximal to CRY2 and MTNR1B with fasting glucose is well established. CRY1/2 and MTNR1B encode proteins that regulate circadian rhythmicity and influence energy metabolism. Here we tested whether season modified the relationship of these loci with blood glucose concentration.
Lichenicolous fungi associated with southern Scandinavian Xanthoria calcicola s.lat.
Chemical food safety of seaweed : Species, spatial and thallus dependent variation of potentially toxic elements (PTEs) and techniques for their removal
The increasing interest in seaweed as a food resource in Western societies raises concerns about associated potentially toxic elements (PTEs), including arsenic, cadmium, mercury, lead, and iodine. Hence, this study examined variation in PTEs by including samples of four different species (Ulva lactuca, Palmaria palmata, Alaria esculenta, and Saccharina latissima) from Ireland, as well as of a sin
Charcot Foot Offloading in Stage 0 Is Associated With Shorter Total Contact Cast Treatment and Lower Risk of Recurrence and Reconstructive Surgery : A Pilot Study
OBJECTIVE: Charcot foot (CF) requires prolonged offloading of the affected foot to decrease the risk of deformity. The earliest phase in active CF (stage 0) is characterized by inflammatory signs without established fractures or skeletal deformity. We investigated whether offloading in stage 0 influences duration of total contact casting (TCC), risk of recurrence, and future need for surgery.RESEA
Pain prevalence and pain relief in end-of-life care - a national registry study
Differentiation of clinical characteristics, mortality, healthcare utilization and costs among four subgroups in a population with heart failure
Plasma Protein Profiling of Incident Cardiovascular Diseases : A Multisample Evaluation
Clusters of carbohydrate-rich foods and associations with type 2 diabetes incidence : a prospective cohort study
Background: About one in ten adults are living with diabetes worldwide. Intake of carbohydrates and carbohydrate-rich foods are often identified as modifiable risk factors for incident type 2 diabetes. However, strong correlation between food variables can make it difficult to identify true associations. The purpose of this study was to identify clusters of carbohydrate-rich foods and analyse thei
Reduced long-term mortality after successful resective epilepsy surgery : A population-based study
A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile
The complement system plays a central role in the pathogenesis of Systemic Lupus Erythematosus (SLE), but most studies have focused on the classical pathway. Ficolin-3 is the main initiator of the lectin pathway of complement in humans, but its role in systemic autoimmune disease has not been conclusively determined. Here, we combined biochemical and genetic approaches to assess the contribution o
The EAT-Lancet Diet Index, Plasma Proteins, and Risk of Heart Failure in a Population-Based Cohort
BACKGROUND: The landmark EAT-Lancet Commission proposed that a planetary health diet is comprised mainly of plant-based foods. However, studies examining whether this diet is associated with heart failure (HF) are currently lacking. In addition, the potential proteomics mechanism on the association between diet and HF warrants further elucidation.OBJECTIVES: This study aims to both examine the ass
Reference ranges for ambulatory heart rate measurements in a middle-aged population
Escape to the future – a qualitative study of physicians’ views on the work environment, education, and support in a digital context
Life’s Essential 8 in relation to self-rated health and health-related quality of life in a large population-based sample : the SCAPIS project
Hydro-meteorological droughts across the Baltic Region : The role of the accumulation periods
Based on the physical and geographical conditions, the Baltic Region is categorised as a humid climate zone. This means that, there is usually more precipitation than evaporation throughout the year, suggesting that droughts should not occur frequently in this region. Despite the humid climate in the region, the study focused on assessing the spatio-temporal patterns of droughts. The drought event
Accumulation of advanced glycation end products in skin and increased vascular ageing in the general population : The Malmö Offspring Study
OBJECTIVES: Advanced glycation end product (AGE) is an established risk marker for diabetic vascular disease, and associated with the degree of diabetes complications, renal failure, and atherosclerosis in middle-aged and older individuals. The relationship between AGEs and aortic stiffness has not been thoroughly examined in the younger general population. We aimed to evaluate the association bet
