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Diabetes is a much more heterogeneous disease than the present subdivision into types 1 and 2 assumes; type 1 and type 2 diabetes probably represent extremes on a range of diabetic disorders. Both type 1 and type 2 diabetes seem to result from a collision between genes and environment. Although genetic predisposition establishes susceptibility, rapid changes in the environment (ie, lifestyle facto

An educational method that is becoming all the more common at colleges and universities is that of the seminar. In the seminar, students write academic papers and reports, present them, and act as opponents on each other’s work. The book covers all the sections that are normally included in the seminar. The learning environment of the seminar is based on a scientific way of thinking and on scienti

Economic and environmental concerns will slow down the expansion of the transmission system in many countries. The addition of new transmission lines will be few and far between. The de-regulation of the power supply will introduce new power flow patterns on the bulk transmission systems. The net result is that the power systems will operate much closer to their transfer limits and operate there m

Packaging has a significant impact on the efficiency of logistical systems and therefore, improvements in the retail supply chain can be achieved through the integration and development of the systems of packaging and logistics. In order to enable these improvements, models are needed that facilitate evaluations along the supply chain in order to grasp the whole picture and avoid sub-optimisations

The point of departure of the dissertation is crime committed when doing cross-border transactions concerning otherwise legal products. The crimes in focus are such which can be described as more organised than everyday crime – but not as organised as required by the widely used and discussed concept of organised crime. From there, a discussion, based on criminal politics, criminal law, crime and

This chapter addresses the question of the growth of accuracy and complexity in L2 French from the perspective of developmental sequences of morphosyntax, developmental stages and linguistic profiling. We examine the systematic growth of morphosyntactic features expressed by the learner during the acquisition process (sequences). Furthermore, we investigate the relatedness of different development

In the first essay of this thesis we develop a model for calculating the net expected value of a swap agreement subject to dual-default risk. The main explanatory variable for the net expected return of a swap is the default intensity of each party measured by the credit rating of the firm. We derive the net expected return of the swap as a function of the credit rating of the firm receiving the f