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SGLT2 inhibitors for patients with type 2 diabetes mellitus after myocardial infarction : a nationwide observation registry study from SWEDEHEART

Background: Sodium-glucose co-transporter 2 (SGLT2) inhibitors have been shown to reduce rates of heart failure hospitalisations and cardiovascular death in patients with type 2 diabetes and prior cardiovascular disease. We hypothesised that SGLT2 inhibitors could provide cardiovascular benefits in the post-myocardial infarction setting. We aimed to investigate cardiovascular outcomes of SGLT2 inh

Lower birth weight indicates higher risk of autistic traits in discordant twin pairs

Background. Autism spectrum disorder (ASD) is a neurodevelopmental disorder of complex etiology. Although strong evidence supports the causal role of genetic factors, environmental risk factors have also been implicated. This study used a co-twin-control design to investigate low birth weight as a risk factor for ASD. Method. We studied a population-based sample of 3715 same-sex twin pairs partici

Pancreatic cancer - cost for overtreatment with gemcitabine.

Gemcitabine has been the standard chemotherapeutic agent in pancreatic cancer. However, two-thirds of pancreatic tumors display low expression of human equilibrative nucleoside transporter 1 (hENT1), which mediates cellular entry of the drug, and do not respond to gemcitabine therapy. The objective was to determine the costs of gemcitabine overtreatment and the cost-effectiveness of hENT1 testing

Risk of Cancer of Unknown Primary after Hospitalization for Autoimmune Diseases.

Cost effectiveness of haemophilia treatment: a cross-national assessment.

Greenhouse gas production in a pond sediment: Effects of temperature, nitrate, acetate and season

Surgical repair of post infarction ventricular septa defects: a national experience

Long-term prediction of prostate cancer up to 25 years before diagnosis of prostate cancer using prostate kallikreins measured at age 44 to 50 years.

Embankment dam seepage evaluation from resistivity monitoring data

Methods for monitoring seepage are important for the safety of embankment dams. Increased seepage may be associated with internal erosion in the dam and internal erosion is one of the main reasons for dam failures. Internal erosion progresses inside the dam and is difficult to detect by conventional methods. Therefore there is a need for new or improved methods. The resistivity method is a non-des

Somatic healthcare utilisation patterns among older people with intellectual disability : an 11-year register study

Primary triage nurses do not divert patients away from the emergency department at times of high in-hospital bed occupancy - a retrospective cohort study

Efficacy versus effectiveness of clinical genetic testing criteria for BRCA1 and BRCA2 hereditary mutations in incident breast cancer

Increasing evidence supports the benefit of identifying BRCA1 and BRCA2 germline mutations in early breast cancer. Selection of patients for genetic testing is based on defined criteria taking individual and family history related factors into account. It is important to make a distinction between efficacy and effectiveness of BRCA testing criteria. Efficacy can be defined as the performance under

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Is the use of sunscreens a risk factor for malignant melanoma?

Venous thromboembolism and cancer risk

Children in Barnahus – an interdisciplinary research study from children’s perspective : Children in Barnahus-Before, during and after being in CH

MAX IV is Ready to Make the Invisible Visible

Befintligt ljus. Carl Henrik Svenstedts filmer 2007 – 12

Teaching Her, Him…or Hir? Challenges for a Cross-Cultural Study.

Energitillförselmodeller för övergång till förnybar och närgenererad energi: en studie över Tjörns kommuns möjlighet att göra en energiomställning

An energy system that relies on fossil fuel is not sustainable. Emissions, such as carbon dioxide, nitric oxide and corpuscles, affect the climate and pollute the air. Furthermore, the supply of oil, coal and natural gas is located a few places worldwide, which can give rise to geopolitical conflicts for access to these areas. This is not a local issue for Tjörn, nor even a national issue for Swed