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Laser Doppler Flowmetry and Imaging: Methodological Studies

Laser Doppler flowmetry (LDF) and laser Doppler imaging (LDI) are modern methods for non-invasive and continuous assessment of skin blood flow. The techniques are based on the phenomenon that monochromatic light transilluminating a perfused tissue is spectrally broadened owing to scattering by moving blood cells. In this study, methodological aspects of the two methods are presented. LDF was used

Cytogenetic studies of normal kidney tissue and renal cell carcinoma

In the present thesis normal kidney tissue and renal cell carcinoma (RCC) were studied by cytogenetic and fluorescence in situ hybridization (FISH) methods to investigate chromosomal aberrations. In the first study, 4 samples of nonneoplastic kidney tissue were cultured for cytogenetic analysis and trisomy 7 was found in all cases in 3-15% of the cells. In the second study, cytogenetic analysis o

Aspects of Optical Broad Band Spectroscopy and Information Extraction - Applications in Medicine and Ecology

The present thesis describes a number of aspects of modern electro-optical measurement technology also known as bio-photonics; this includes instrumentation, applications, sample interaction and data interpretation. The methods employed operate over several domains, and light measurements are discretized both in intensity, space, angle, time, polarization and energy. Mainly the spectral domain is

Waterfowl herbivory on submerged macrophytes in eutrophic lakes

Submerged macrophytes are thought to stabilize clear-water states of shallow lakes. The aim of this thesis was to elucidate how waterfowl herbivory can affect abundance, distribution and species composition of submerged macrophytes in eutrophic lakes. I found that in a lake with sparse vegetation, which was in a colonization phase, small plants were uprooted and large plants were heavily grazed up

Experimental Stroke and Neurotrophins: Regulation, function and gene transfer of neurotrophins in rat and mouse models of focal cerebral ischemia

Stroke caused by focal cerebral ischemia is a major cause of death and neurological disability in humans. The forebrain region most commonly affected by ischemic incidents is that supplied by the middle cerebral artery. In this thesis, neuronal cell death has been investigated using immunohistochemistry for identification of specific neurons and unbiased counting methods after transient occlusion

Perspectives of anxiety in stressful environments : Prospective studies in real-life settings

The present thesis deals with perspectives of anxiety experienced in stressful environments. As such two major issues are addressed. The first issue is whether increased trait anxiety during work in a high-stress environment is related to impaired performance on executive control tasks. The second issue is whether the characteristic of a stressor and pre-stress individual differences in executive

Water-swelling tablets based on hydrophobically modified poly(acrylic acid) - Effects of amphiphiles on swelling and drug release

An important issue within the pharmaceutical world today is the increasing number of poorly soluble drugs. These often show a low bioavailability and a susceptibility to varying conditions in the intestine. Hydrophobically modified poly (acrylic acid) (HMPAA), commercially available as Pemulen TR2, has shown promising abilities to control the release of especially poorly soluble substances. In thi

Studies on chondrocyte integrins and mechanical signaling

Integrins are a family of cell surface receptors known to bind matrix proteins and to mediate signals such as mechanical signals between the cell and the surrounding matrix. We have studied integrins that are expressed by chondrocytes, with specific focus on the integrins that interact with the cartilage matrix protein collagen type II. It was found that chondrocytes isolated from articular cartil

Evolution of Vertebrate Eyes: a study on lens suspension and optical proterties

Many fishes have well-developed visual systems with color vision capabilities. The crystalline lens is the major refractive element in a fish eye since the cornea is optically inactive underwater. A typical fish eye has a large pupil and a lens of short focal length, features that increase light gathering ability. They lead also to short depth of focus, which makes the eye particularly susceptible

The ubiquity and type diversity of papillomaviruses in normal skin

Papillomaviruses are a diverse, epitheliotropic group of viruses. Some genotypes are the main cause of anogenital cancer in humans; others can induce skin lesions. In order to investigate the occurrence of subclinical skin infections with human papillomavirus (HPV), a pair of degenerate primers (FAP59/64) was designed. Moist cotton-tipped swabs were used as a gentle method of sample collection. Di

Modeling and simulation of electro-viscoelastic polymers

The electroactive polymer materials considered in this work react to electric stimuli by producing deformations. In some cases, the electrically induced deformations are moderate, while in other cases they can be very large and the specimen is stretched to more than twice its original length. The latter response is seen in so called dielectric elastomer actuators (DEA). The possibility of very lar

Development of Magnetomotive Ultrasound Imaging

The earlier abnormalities coupled with disease can be discovered in the body, the larger is the chance to survive the disease. Molecular imaging is a growing research field which aims to detect these abnormalities at a molecular level, when the chance of survival is still high. The main idea of molecular imaging is to use target specific contrast agents that accumulate at the diseased region at a

Chronic hepatitis C infection. With special reference to prevalence, aggravating factors and longterm outcome

Since the discovery of hepatitis C virus (HCV) in 1989, it has proved to be a formidable health problem with a major impact on morbidity and mortality throughout the world. In this investigation, patients with chronic hepatitis C infection have been studied with special reference to prevalence, aggravating factors and longterm outcome. The prevalence of HCV infection was high (approximately 10 %)

Hydrogen Production by Caldicellulosiruptor species: The Organism and the Metabolism

Hydrogen holds a great promise as an efficient and clean future energy carrier due to its high energy density and lack of pollutant generation. Anaerobic degradation of organic substrates by heterotrophic microorganisms enables the production of hydrogen from a wide spectrum of agricultural feedstock and waste products. Using thermophiles in this process is preferable for maximizing the substrate

Modeling of material behavior in metal forming

With an increasing demand to improve efficiency and to cut costs, the industry is constantly seeking to reduce the time and money spent in product development and manufacturing. Use of computer-based simulations has become more or less a standard tool to meet this demand. Cost reduction is in this way made possible by for example shortened product development cycles, less need for expensive protot

Dynamic Modelling of Emulsification in High-Pressure Homogenizers

Different approaches and sub-models for the modelling of emulsification in a high-pressure homogenizer are reviewed and compared in terms of both practical aspects and how well they describe what is currently known on the emulsification process in general and on high-pressure homogenization in particular. Special effort is devoted to comparing the model developments presented in the appended paper

Graduate school thesis info

1099-506417187-1.pdf 
INFO GRADUATE SCHOOL, FACULTY OF SOCIAL SCIENCES, LUND UNIVERSITY Version 1.3 – January 2017 Information about the thesis process at Graduate School to Department planners | Supervisors | Examiners An online and always up-to-date version can be found on the Graduate School web site (staff resources) CHAPTER 1 The thesis process at Graduate School At Graduate School the thesis

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/graduate_school_thesis_info.pdf - 2025-12-29

Dunnett et al part ii brain res 1981

PII: 0006-8993(81)91007-6 Brain Research, 229 (1981) 457-470 457 Elsevier/North-Holland Biomedical Press B E H A V I O U R A L RECOVERY F O L L O W I N G T R A N S P L A N T A T I O N OF SUBS- T A N T I A N I G R A IN RATS SUBJECTED TO 6-OHDA LESIONS OF T H E N I G R O S T R I A T A L PATHWAY. II. B ILATERAL LESIONS STEPHEN B. DUNNETT*, ANDERS BJORKLUND, ULF STENEVI and SUSAN D. IVERSEN Department

https://www.wnc.lu.se/sites/wnc.lu.se/files/dunnett_et_al_part_ii_brain_res_1981.pdf - 2025-12-29

Kapitalkravet i ABL - Bör kapitalkravet avskaffas för att göra aktiebolagslagen konkurrenskraftig?

För att bilda ett privat aktiebolag i Sverige krävs det att grundarna tillskjuter 25 000 kr, enligt Aktiebolagslagen (2005:551). Det lagstadgade kravet på aktiekapital har främst ansetts varit motiverat med hänsyn till dess funktion som borgenärsskydd, men numera anser den svenska lagstiftaren att det är aktiekapitalets funktion som seriositetsspärr som är av störst betydelse. Mot dessa funktioner

Surrogatmödraskap och barnets bästa - Om svensk reglering av surrogatmödraskap och dess förenlighet med barnkonventionen och principen om barnets bästa

Denna uppsats syftar att undersöka gällande rätt vid surrogatarrangemang samt att redogöra för principen om barnets bästa med fokus på barnkonventionen. Principen om barnets bästa är en allmän princip som förekommer inom svensk rätt och i barnkonventionen. Surrogatmödraskap innebär att en kvinna bär ett barn med avsikten att lämna det ifrån sig till efter barnets födsel. Svensk rätt tillåter int