Filtyp
Acute pancreatitis (AP) is a common disorder where underlying mechanisms for the local initiating events in the pancreas, the systemic dissemination of the inflammatory response and the remote organ dysfunction still are unclear. The aim of the present study was to further characterize the dynamics and sequence of the immune response in AP, and to determine the cellular origin of the initiating ev
Two putative cyclodextrinases (CDases) were amplified from two moderate thermophiles isolated in Iceland: Anoxybacillus flavithermus and Laceyella sacchari. They were cloned, expressed and characterized. The expression of the former was optimized in E. coli by using a solubility-enhancing tag, NusA, and tuning of inducer concentration in the expression strain Tuner(DE3). The CDases were optimally
A probabilistic framework used in studying collective decision making is the uncertain dichotomous choice model. The model is essentially characterized by two components: the organizational structure and the voting process. By organizational structure, we refer to a group composed of members with common objectives and who are tasked to choose one of the two given alternatives, one of which is assu
Development is a contentious concept, praised by some for enabling progress and criticised by others for perpetuating global power imbalances. Development assistance tends to strengthen the donor-recipient dependency, which, according to critics, primarily serves the interests of the Global North while neglecting the needs of the Global South. Mainstream market-driven strategies have exacerbated i
This report presents an integrated simulation-based approach to study the on-site production of concrete frameworks by considering the multiple effects of weather on work task productivity and concrete curing process. The suggested approach enable to systematically study how different weather conditions and the use of climate-improved concrete in combination with different methods to shield concre
In Sweden there are many people who take the food on our tables for granted, there is rarely anyone who reflects on the fact that it was hard work behind. The situation has not always been like that. During the late 1800s there were still many people living in rural areas and their livelihood was farming. Their jobs and mundane chore was to produce, if not the whole, but parts of the food that wou
This paper explores how marketing is conducted in for-profit social ventures. Knowledge regarding the for-profit social context is considered rather limited given that it has been largely marginalized by being associated either to the fully for-profit or solely non-profit extremes. In that respect, much of the existing literature has not to acknowledge the unique challenges that a dual mission, su
The investing industry has historically been built around the sole purpose to bring superior financial returns to investors. Due to the rising concern towards global social and environmental issues, investments promoting sustainable development have grown popular. Centring sustainable investments debate is the strategy impact investing. The strategy originates from more traditional ethical investm
Denna uppsats undersöker hur formatet i en televiserad slutdebatt påverkar bilden av politik. Uppsatsen diskuterar moderatorns roll och på vilket sätt partiledarna har möjlighet att styra och sätta sin politik på dagordningen. Uppsatsen behandlar även hur partiledarna använder ethos, pathos och logos i sin argumentation får att stärka sin egen och partiets trovärdighet för att sätta sin politik på
IntroductionThis study is part of an international collaboration that investigates teachers’ attitudes and responses to vignettes depicting school bullying situations. As per Bandura's model of reciprocal determination, attitudes and behavior in these situations can be influenced by individual and contextual factors. This study specifically examines several factors related to teachers ‘professio
Critically ill patients in intensive care units (ICU) often have coagulation disturbances. Clinical manifestations such as thromboembolism and/or bleeding may result from activation and consumption of coagulation factors and inhibitors. Disseminated intravascular coagulation (DIC) is a severe condition with an often-poor prognosis. Global haemostatic tests are inexpensive, widely available, and ma
This thesis treats various aspects of the measurement of trace components in aqueous solutions with Fourier transform infrared spectroscopy. This technique has several applications from such diverse fields as dairy industry and biomedical optics. The use of infrared spectroscopy for trace component quantification is made difficult by the large absorption of water which dominates the spectrum. The
Cardiac pumping physiology is important for understanding the pathophysiology of patients with cardiac disease. MRI gives the opportunity to measure volumes and flow non-invasively with high accuracy and precision. This thesis examines some aspects on cardiac pumping physiology. Study I showed that the total heart volume in humans decreases during systole by ~8 % (range 5-11 %), and anatomically i
In this thesis I study two-dimensional geometric optimization problems for which it is difficult to find efficient, exact, deterministic algorithms. All known solutions to these problems require time that is exponential in the total size of the input. The work done in this thesis is a contribution to the research directed at attacking and coping with such NP hard problems in computational geometry
Summary: For religious Sikhs, the Guru Granth Sahib is a holy scripture which enshrines ontologically divine words and the teaching and revelatory experiences of historical human Gurus. Simultaneously the Sikhs have taken the concept of a sacred scripture much further than any other religious community by treating the Guru Granth Sahib as a living Guru invested with spiritual authority and agency
Hematopoietic stem cells (HSCs) are defined by their capacity to self-renew and differentiate into all hematopoietic cell lineages. Postnatally, HSCs reside predominantly in the bone marrow and are relatively rare, but important cells because of their therapeutic potential in bone marrow transplantation protocols and in their involvement in the origin of certain leukemias. To study how various gen
