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Rapid ecosystem response to abrupt climate changes during the last glacial period in western Europe, 40-16 ka

We present a high-resolution and independently dated multiproxy lake sediment record from the paleolake at Les Echets in southeastern France that displays synchronous changes in independent limnic and terrestrial ecosystem proxies, in concert with millennial-scale climate oscillations during the last glacial period. Distinct lake-level fluctuations, low lake organic productivity, and open, treeles

A review on ergonomics of headgear: Thermal effects

The thermal effects related to wearing headgear are complex and different studies have investigated single parts of this topic. This review aims at summarizing the different findings to give a complete overview on this topic as well as to suggest new perspectives. Headgear increases head insulation and therefore is mainly problematic under warm conditions, which is the focus of this review. Helmet

Experimental investigation of the spin reorientation of Co/Au based magnetic nanodot arrays

(Co/Au) and (Au/ Co/ Au) nanomagnet arrays grown on nanostructured self-organized SiGe templates have been characterized by means of x-ray photoemission electron microscopy, x-ray magnetic circular dichroism, and by extended x-ray absorption spectroscopy using synchrotron radiation. In-plane magnetization is observed at room temperature for practically all Co thicknesses, a stable macroscopic perp

Assessing Multivariate Constraints to Evolution across Ten Long-Term Avian Studies.

In a rapidly changing world, it is of fundamental importance to understand processes constraining or facilitating adaptation through microevolution. As different traits of an organism covary, genetic correlations are expected to affect evolutionary trajectories. However, only limited empirical data are available. We investigate the extent to which multivariate constraints affect the rate of adapta

Foreign language perceptual curiosity : construct, measurement, and applications

Learning a language is a creative process. It involves novelty and imagination. While curiosity can be highly beneficial, research is limited. Studies so far conducted have explored epistemic curiosity as a trait-like disposition. In contrast, the current study focuses on perceptual curiosity (PC). PC is a situational response evoked by novelty, complexity and ambiguities in sensory stimulation. P

MIRD Pamphlet No. 32 : A MIRD Recovery Coefficient Model for Resolution Characterization and Shape-Specific Partial-Volume Correction

Accurate quantification in emission tomography is essential for internal radiopharmaceutical therapy dosimetry. Mean activity concentration measurements in objects with diameters less than 10 times the full width at half maximum of the imaging system’s spatial resolution are significantly affected (>10%) by the partial-volume effect. This study develops a framework for PET and SPECT spatial resolu

Efficacy and safety of varenicline and bupropion, in combination and alone, for alcohol use disorder : a randomized, double-blind, placebo-controlled multicentre trial

Background: Alcohol use disorder (AUD) is associated with an enormous burden of disease and cost to society. The dopamine deficiency hypothesis posits that negative reinforcement generated by a low brain dopamine state drives ethanol intake. Here, we evaluated the efficacy and safety of combined administration of two dopamine-enhancing drugs, varenicline (a partial nicotinic acetylcholine receptor

Association Between Prescribed Dosage of Resistance Exercise and Change in Pain and Physical Function in Knee Osteoarthritis : A Systematic Review With Meta-Regression

Objective: To assess whether there is an association between total prescribed dosage of resistance exercise (volume, frequency, intensity, and duration) and change in pain and physical function in individuals with knee osteoarthritis (OA). Method: A systematic review with meta-regression was conducted, searching MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials until December

Gastric MUC5AC and MUC6 are large oligomeric mucins that differ in size, glycosylation and tissue distribution.

Gastric MUC5AC and MUC6 mucins were studied using polyclonal antibodies. Immunohistochemistry showed MUC5AC to originate from the surface epithelium, whereas MUC6 was produced by the glands. Mucins from the surface epithelium or glands of corpus and antrum were purified using CsCl/4M guanidinium chloride density-gradient centrifugation. MUC5AC appeared as two distinct populations at 1.4 and 1.3 g/

Low-power voltage-controlled oscillators in 90-nm CMOS using high-quality thin-film postprocessed inductors

Wafer-level packaging (WLP) technology offers novel opportunities for the realization of high-quality on-chip passives needed in RF front-ends. This paper demonstrates a thin-film WLP technology on top of a 90-nm RF CMOS process with one 15-GHz and two low-power 5-GHz voltage-controlled oscillators (VCOs) using a high-quality WLP or above-IC inductor. The 5-GHz VCOs have a power consumption of 0.3

Randomized trial of plasma exchange or high-dosage Methylprednisolone as adjunctive therapy for severe renal vasculitis

Systemic vasculitis associated with autoantibodies to neutrophil cytoplasmic antigens (ANCA) is the most frequent cause of rapidly progressive glomerulonephritis. Renal failure at presentation carries an increased risk for ESRD and death despite immunosuppressive therapy. This study investigated whether the addition of plasma exchange was more effective than intravenous methylprednisolone in the a

The Syntax of Past Participles. A Generative Study of Nonfinite Constructions in Ancient and Modern Italian

The purpose of this thesis is double. First, it will be shown that a number of problems of the syntax of ancient, literary Italian lend themselves readily to an analysis in terms of the Theory of Principles and Parameters. Second, the Italian data, supported by comparative remarks on modern Romance and Germanic, confirm the essential correctness of one particular version of the above theory namely

The Substituted Judgment Standard. Studies on the Ethics of Surrogate Decision Making

Popular Abstract in Swedish Beslutsinkompetenta patienter behöver en ställföreträdande beslutsfattare som kan fatta vårdbeslut för deras räkning. En av de etiska frågor som aktualiseras i detta sammanhang är vilka riktlinjer som bör gälla för sådant beslutsfattande. Enligt ?the Substituted Judgment Standard? (SJS) bör en ställföreträdare fatta det beslut som patienten själv hade fattat, om denne hPatients who are incompetent need a surrogate decision maker to make treatment decisons on their behalf. One of the main ethical questions that arise in this context is what standard ought to govern such decision making. According to the Substituted Judgment Standard (SJS), a surrogate ought to make the decision that the patient would have made, had he or she been competent. Although this standard

Gene profiling reveals a contact allergy signature in most positive Amerchol L-101 patch-test reactions

Background: Diagnosis of contact allergy (CA) to Amerchol L-101 (AL-101), a marker for lanolin allergy, is problematic. Positive patch-test reactions are frequently doubtful or weakly positive and difficult to associate with clinical relevance. Objective: To gain further insight on the allergic or irritant nature of skin reactions induced by AL-101 patch test. Methods: We re-tested in a dose–respo

Lithium recovery through WS2 nanofillers-promoted solar photothermal membrane crystallization of LiCl

The recovery of raw materials represents one of the greatest challenges for a circular economy. Especially, the increased demand for lithium in the last years for its critical role in Li-ion batteries implies the need for green technology for Li recovery able to address market requests. Here, we devise and implement a new technology exploiting excitons-based light-to-heat conversion promoted by WS

Accurate Indoor Positioning Based on Learned Absolute and Relative Models

To improve the accuracy of indoor positioning systems it can be useful to combine different types of sensor data. This paper describes deep learning methods both for estimating absolute positions and for performing pedestrian dead reckoning, and then how to combine the resulting estimates using weighted least squares optimization. The positioning model is based on a custom neural network which use

105 mp221 krischer diab care 2019

Predicting Islet Cell Autoimmunity and Type 1 Diabetes: An 8-Year TEDDY Study Progress Report Predicting Islet Cell Autoimmunity and Type 1 Diabetes: An 8-Year TEDDY Study Progress Report https://doi.org/10.2337/dc18-2282 OBJECTIVE Assessment of the predictive power of TEDDY-identified risk factors for islet autoimmunity (IA), the type of autoantibody appearing first, and type 1 diabetes (T1D). RE

https://www.teddy.lu.se/sites/teddy.lu.se/files/105_mp221_krischer_diab_care_2019.pdf - 2026-05-20

117 mp224 li et al. metabolomics diabetes

Longitudinal Metabolome-Wide Signals Prior to the Appearance of a First Islet Autoantibody in Children Participating in the TEDDY Study Longitudinal Metabolome-Wide Signals Prior to the Appearance of a First Islet Autoantibody in Children Participating in the TEDDY Study Qian Li,1 Hemang Parikh,1 Martha D. Butterworth,1 Åke Lernmark,2 William Hagopian,3 Marian Rewers,4 Jin-Xiong She,5 Jorma Toppar

https://www.teddy.lu.se/sites/teddy.lu.se/files/117_mp224_li_et_al._metabolomics_diabetes.pdf - 2026-05-20

Eye Tracking-Based Speech Label Estimation for Auditory Attention Decoding with Portable EEG

In this study, we investigate integrating eye tracking with auditory attention decoding (AAD) using portable EEG devices, specifically a mobile EEG cap and cEEGrid, in a preliminary analysis with a single participant. A novel audiovisual dataset was collected using a mobile EEG system designed to simulate real-life listening environments. Our study has two main objectives: (1) to use eye tracking