Filtyp
A family history of cutaneous melanoma ('melanoma') is a well-established risk factor for melanoma. However, less is known about the possible familial associations of melanoma with other discordant cancers. A risk for discordant cancer may provide useful information about shared genetic and environmental risk factors and it may be relevant background data in clinical genetic counseling. Using the
It has previously been shown that cobalt accumulates in the myocardium of rats, mainly the sarcoplasmic reticulum (SR) and the mitochondrial inner membrane. In order to investigate the mode of accumulation of cobalt in the SR, rats were given a dietary cobalt supplementation of 40 mg of CoSO4 × 7 H2O kg-1 body wt, after which the rats were sacrificed and the sarcoplasmic reticulum was isolated. Th
In this study the aim was, through interviews, to disclose 13 nurses' personal knowledge about the patients, themselves, and care provision, using a phenomenological-hermeneutic analysing method. Caring for people with severe dementia meant an intertwined life world emanating from making and doing together and the delicate interpretative work that the care provision required. The intertwined life
The production cross sections of the inclusive Drell-Yan processes W-+/- -> l nu and Z/gamma* -> ll (l = e, mu) are measured in proton-proton collisions at root s = 7 TeV with the ATLAS detector. The cross sections are reported integrated over a fiducial kinematic range, extrapolated to the full range, and also evaluated differentially as a function of the W decay lepton pseudorapidity and the Z b
The influence of electrostatic interactions on the dynamic properties of complexes containing DNA and mixtures of cationic- (DDA) and zwitterionic (DLPC) lipids are studied by means of NMR. The systems are arranged in lamellar membrane stacks intercalated by DNA molecules. This is confirmed by 31P-NMR, where a superposition of an axially symmetric powder pattern arising from the phospholipid membr
Spring water, however, is often formed in complex geological formations and therefore it is difficult to determine the catchment area contributing to the flow. The Sayanokami spring, located in western part of Fukuoka City, Japan, is such a spring and an important water resource for the local agriculture. In order to better understand the hydrological properties of infiltration and groundwater pro
Single-shot transients and deep-level transient spectroscopy are used to investigate the origins of capacitance hysteresis in n-doped InAs nanowire/HfO2 capacitors. Capacitance transients with a characteristic time in the order of 100 mu s are attributed to emission from electron traps, located in the oxide film. The trap energy is determined to be in the range from 0.12 to 0.17 eV with capture cr
In order to compare measurements in different laboratories and with different models and measuring principles a small Round Robin test was suggested. 8 test institutions were able to join the study (with foot model sizes from 254 mm to 275 mm and test boot sizes from 41 to 44). We got also a declaration of interest from several other institutes that were not able to carry out the tests. A database
E-business is becoming more and more common today. The predictions of future growth give clear indications that companies will use e-business more and more. However in the growth of e-business it has been identified that there is a common lack of understanding in customer needs and logistics. In order to reduce some of this non-understanding this thesis seeks answers to the following question: - H
Background: Several attempts to increase the locoregional control in locally advanced lung cancer including concurrent chemotherapy, accelerated fractionation and dose escalation have been made during the last years. As the EGFR directed antibody cetuximab has shown activity concurrent with radiotherapy in squamous cell carcinoma of the head and neck, as well as in stage IV NSCLC combined with che
The objective of this study was to calculate indicative ranges of production costs and assess the main sources of cost for a number of energy crops, both annual and perennial, on a regional level in Europe. The production costs were calculated in terms of the economic compensation required by the farmer in order to grow the crop, and therefore include not only the cost of cultivation, but also the
In order to convince both policy makers and the general public to engage in climate change mitigation activities, it is crucial to communicate the inherent risks in an effective way. Due to the complexity of the system, mitigation activities cannot completely rule out the possibility of the climate reaching a dangerous tipping point but can only reduce it to some unavoidable residual risk level. W
Background: The mechanisms underlying the obesity-cancer relationship are incompletely understood. This study aimed to characterise metabolic signatures of greater body size and to investigate their association with two obesity-related malignancies, endometrial and colorectal cancers, and with weight loss within the context of an intervention study. Methods: Targeted mass spectrometry metabolomics
In 1997 John Broome presented the Collapsing Argument that was meant to establish that non-conventional comparative relations (e.g., “parity,” “imprecise equality,” “incommensurability”) cannot exist. Broome's argument has faced a lot of scrutiny and a certain type of counterexample has been used to undermine it. Most of the counterexamples focus on the Collapsing Principle which plays a central r
The incidence of narcolepsy type 1 (NT1) increased in Sweden following the 2009-2010 mass-vaccination with the influenza Pandemrix-vaccine. NT1 has been associated with Human leukocyte antigen (HLA) DQB1*06:02 but full high-resolution HLA-typing of all loci in vaccine-induced NT1 remains to be done. Therefore, here we performed HLA typing by sequencing HLA-DRB3, DRB4, DRB5, DRB1, DQA1, DQB1, DPA1
Background: Neuropathological studies have linked tau aggregates to neuronal loss. To describe the spatial distribution of neurofibrillary tangle pathology in post-mortem tissue, Braak staging has been used. The aim of this study was to examine in vivo associations between tau pathology, quantified with [18F]flortaucipir PET in regions corresponding to Braak stages, and atrophy across the Alzheime
Background: Due to lack of knowledge about seasonal influenza vaccine effectiveness (SIVE) against laboratory-confirmed influenza in patients aged ≥65 years a study to measure SIVE in patients admitted to hospital due to severe acute respiratory infection (SARI) in Lithuania during the 2015-2018 was conducted.Materials/methods: A test-negative case-control study was performed between 2015-2016 and
PURPOSE: To evaluate the outcomes of total endovascular aortic arch repair using three-vessel inner branch stent-grafts for aneurysms and chronic dissections.METHODS: We reviewed the clinical data and outcomes of consecutive patients treated by total endovascular aortic arch repair at eight academic centers using three-vessel inner branch stent-grafts (William Cook Europe, Bjaeverskov, Denmark) be
Purpose: In the literature there is limited knowledge about how to prepare students for a corporate entrepreneurial career. The purpose is therefore to develop a framework for understanding the role corporate development projects play in corporate entrepreneurship education, and to examine the potential role of the design of the project. The study defines a corporate development project as a proje
The complex pseudodielectric function of Ge and Si from femtosecond pump-probe spectroscopic ellipsometry with 267, 400, and 800 nm pump-pulse wavelengths is analyzed by fitting analytical lineshapes to the second derivatives of the pseudodielectric function with respect to energy. This yields the critical point parameters (threshold energy, lifetime broadening, amplitude, and excitonic phase angl
