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News and events from 2022

News updates and events from the 2030 Graduate School. NewsDecemberReduced flow of plasticsAt Helsingborg's hospital, doctors have switched from disposable to reusable items and reduced the flow of plastics, writes Sjukhusläkaren. The Agenda 2030 PhD student Linn Boberg researches plastic articles in healthcare and is interviewed in the article.Tog bort onödiga verktyg - minskade plastflödet i ope

https://www.agenda2030graduateschool.lu.se/activities/news-2025/news-and-events-2022 - 2025-07-01

Structure of the human ClC-1 chloride channel

ClC-1 protein channels facilitate rapid passage of chloride ions across cellular membranes, thereby orchestrating skeletal muscle excitability. Malfunction of ClC-1 is associated with myotonia congenita, a disease impairing muscle relaxation. Here, we present the cryo-electron microscopy (cryo-EM) structure of human ClC-1, uncovering an architecture reminiscent of that of bovine ClC-K and CLC tran

ECG Quantification of Myocardial Scar in Cardiomyopathy Patients With or Without Conduction Defects Correlation With Cardiac Magnetic Resonance and Arrhythmogenesis

Background-Myocardial scarring from infarction or nonischemic fibrosis forms arrhythmogenic substrate. The Selvester QRS score has been extensively validated for estimating myocardial infarction scar size in the absence of ECG confounders. but has not been tested to quantify scar in patients with hypertrophy, bundle branch/fascicular blocks, or nonischemic cardiomyopathy. We assessed the hypothese

PcoB is a defense outer membrane protein that facilitates cellular uptake of copper

Copper (Cu) is one of the most abundant trace metals in all organisms, involved in a plethora of cellular processes. Yet elevated concentrations of the element are harmful, and interestingly prokaryotes are more sensitive for environmental Cu stress than humans. Various transport systems are present to maintain intracellular Cu homeostasis, including the prokaryotic plasmid-encoded multiprotein pc

Discovery of epi-enprioline as a novel drug for the treatment of vincristine resistant neuroblastoma

Neuroblastoma is a childhood solid tumour originating from undifferentiated neural progenitor cells of the sympathetic nervous system. Drug resistance of childhood cancer neuroblastoma is a serious clinical problem. In the present study, we aimed to identify novel drugs that can inhibit the growth and survival of chemoresistant neuroblastoma. High-throughput screening identified a small molecule,

Impact of site-specific conjugation strategies on the pharmacokinetics of antibody conjugated radiotherapeutics

Antibody radionuclide conjugates are an emerging modality for targeted imaging and potent therapy of disseminated disease. Coupling of radionuclides to monoclonal antibodies (mAbs) is typically achieved by applying non-site-specific labelling techniques. With the ambition of reducing variability, increasing labelling efficacy and stability, several site-specific conjugation strategies have been de

How Do Modifiable Risk Factors Affect Alzheimer's Disease Pathology or Mitigate Its Effect on Clinical Symptom Expression?

Epidemiological studies show that modifiable risk factors account for approximately 40% of the population variability in risk of developing dementia, including sporadic Alzheimer's disease (AD). Recent findings suggest that these factors may also modify disease trajectories of people with autosomal-dominant AD. With positron emission tomography imaging, it is now possible to study the disease many

Biallelic KRT5 mutations in autosomal recessive epidermolysis bullosa simplex, including a complete human keratin 5 “knock-out”

Epidermolysis bullosa simplex (EBS) is usually inherited as an autosomal dominant disease due to monoallelic gain-of-function mutations in KRT5 or KRT14. Although autosomal recessive forms of EBS have been associated with mutations in at least 10 genes, recessive EBS due to homozygous biallelic KRT5 mutations has not been reported previously; it has been hypothesized that it would result in prenat

Genetic regulation of spermine oxidase activity and cancer risk : a Mendelian randomization study

Spermine oxidase (SMOX) catalyzes the oxidation of spermine to spermidine. Observational studies have reported SMOX as a source of reactive oxygen species associated with cancer, implying that inhibition of SMOX could be a target for chemoprevention. Here we test causality of SMOX levels with cancer risk using a Mendelian randomization analysis. We performed a GWAS of spermidine/spermine ratio to

DBT-skills system for cognitively challenged individuals with self-harm: a Swedish pilot study

Background: Dialectical behavior therapy (DBT) is an evidence-based treatment for self-harm and emotion regulation difficulties. A modified version, DBT-Skills System (DBT-SS), has been developed in the USA for individuals with cognitive difficulties. The present study is a pilot study, testing the DBT-SS in a Swedish context.Methods: Six participants were treated with individual therapy and group

Kvinnlig könsstympning och manlig omskärelse - en studie av regleringen avseende genitala ingrepp

Hur rättfärdig är icke lagen: den förbjuder såväl den rike som den fattige att sova under broarna och tigga bröd. Detta kända citat av författaren Anatole France illustrerar inledningsvis en övergripande del av mitt syfte med denna uppsats. Lagen ska i sin utformning som utgångspunkt vara generell, förutsägbar och lika för alla – ändock drabbar den oundvikligen olika (grupper) av befolkningen påThe law, in its majestic equality, forbids the rich as well as the poor to sleep under bridges, to beg in the streets, and to steal bread. This famous quotation by the author Anatole France will serve as an introduction to a major part of the scope of this essay. The law shall in its form be general, foreseeable and applied equably in regard to all citizens – despite this, the law strikes differ

Microsoft Word - HILMA 2008-04-dd.doc

Microsoft Word - HILMA 2008-04-dd.doc HILMA Historiska Institutionen i Lund Meddelar Att… Årgång 33, 2007/08, Nr 12, 2008-04-dd Underlagen till HILMA förvaras i pärmar som står i rum 209, på hyllan ovanför faxen. Där hittar du ytterligare information om seminarier, anställningsvillkor, stipendier och annat samt ansök- ningsblanketter i förekommande fall. De sistnämnda, som är samlade i en separat

https://www.hist.lu.se/fileadmin/_migrated/content_uploads/hilma_vt08_18.pdf - 2025-06-30

Ny student

VIKTIG OCH ANVÄNDBAR INFORMATION FÖR STUDENTER VID EKONOMIHÖGSKOLAN Börja här – 4 viktiga stegHitta informationNy student på Ekonomie kandidatprogrammetNy student på Systemvetenskapligt kandidatprogramNy student på magisterprogrammet Information SystemsDatum och schemanIT (internet, skrivare, digitala verktyg)Ekonomihögskolans campusStöd och hjälp för dig som studentStudentlivRättigheter och skyld

https://www.ehl.lu.se/studera-vid-ekonomihogskolan/studentwebben/ny-student - 2025-07-01

Ky-master kursplan arr komp

KY-master_kursplan_arr_komp Kyrkomusikerutbildning arrangering/komposition 120 hp Utbildningsplan 1 Identifikation • Programmets namn och inriktning: Kyrkomusikerutbildning med inriktning arrangering och komposition, avancerad nivå • Omfattning i högskolepoäng: 120 hp. • Programkod: KAKYM. • Inriktning: ARKO – arrangering/komposition • Utbildningsplanen är beslutad i Konstnärliga fakultetsstyrelse

https://www.mhm.lu.se/sites/mhm.lu.se/files/ky-master_kursplan_arr_komp.pdf - 2025-07-03

Ky-master kursplan orgel klaver

KY-master_kursplan_orgel_klaver Kyrkomusikerutbildning orgel och klaver 120 hp Utbildningsplan 1 Identifikation • Programmets namn och inriktning: Kyrkomusikerutbildning med inriktning orgel och klaver, avancerad nivå • Omfattning i högskolepoäng: 120 hp. • Programkod: KAKYM. • Inriktning: ORKL – orgel och klaver • Utbildningsplanen är beslutad i Konstnärliga fakultetsstyrelsen den 12 november 200

https://www.mhm.lu.se/sites/mhm.lu.se/files/ky-master_kursplan_orgel_klaver.pdf - 2025-07-03

Forskningsgruppen Miljöpolitik

På den här sidan presenteras forskningsgruppen Miljöpolitik (EPRG), vilka som är sammankallande, forskare i gruppen, publikationer knutna till gruppen, pågående projekt, doktorandprojekt, postdoktorers projekt, relaterad utbildning på och utanför institutionen samt kommande seminarier. Om gruppenEnvironmental Politics Research Group (EPRG) är en av de ledande miljöforskningsgrupperna i Europa. Sam

https://www.svet.lu.se/forskning/forskningsgrupper/forskningsgruppen-miljopolitik - 2025-07-01

Terminstider-lasaret-2023-24

Terminstider läsåret 2023/24 Beslut Sida 1 av 3 Student och utbildning Diarienummer U 2022/287 2022-06-20 Reviderad: 2022-12-01 Terminstider läsåret 2023/24 För läsåret 2023/24 gäller följande terminstider: Höstterminen 2023 pågår från och med måndagen den 28 augusti 2023 till och med söndagen den 14 januari 2024. Vårterminen 2024 pågår från och med måndagen 15 januari 2024 till och med söndagen d

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2022-12/Terminstider-lasaret-2023-24.pdf - 2025-07-03