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The molecular chaperone αB-crystallin is a small heat shock protein that inhibits the aggregation of, among others, Aβ42 and α-synuclein. These proteins are major hallmarks of Alzheimer's and Parkinson's disease, respectively. In order to understand the mechanism with which αB-crystallin performs its chaperone function it is essential to characterize its self-assembly in terms of aggregate size di

Till följd av höga växthusgasutsläpp har klimatförändringarnas konsekvenser fastställts av FNs klimatpanel IPCC som ett omfattande hot mot både människans och planetens välbefinnande. För att Parisavtalets mål om att begränsa den globala uppvärmningen till 1,5 grader celcius ska uppnås, krävs snabba och resoluta utsläppsminskningar utan motstycke. Basindustrin, däribland stålindustrin som står för

This paper presents the ongoing design and evaluation of an audio-haptic drawing program that allows visually impaired users to create and access graphical images. The application is developed in close collaboration with a user reference group of five blind/low vision school children. The objective of the application is twofold. It is used as a research vehicle to investigate user interaction tech

Popular Abstract in Swedish Inom området diagnostisk nuklearmedicin används radioaktiva läkemedel som ges (administreras) till patienterna i syfte att diagnostisera ett antal olika sjukdomstillstånd. Då man tar fram nya radioaktiva läkemedel för användning inom diagnostisk nuklearmedicin handlar det många gånger om att uppskatta mängden av ett visst upptag av radiofarmakat i olika organ och vävnadAn essential part of the development of new radiopharmaceuticals for use in diagnostic nuclear medicine is the determination of its biokinetic properties. The uptake and turn-over of the radiopharmaceutical in the source organs is of great interest since this could determine whether the radiopharmaceutical would be suitable for clinical use or not. It is also important that the biokinetics and dos

Background: The fractalkine/CX3C chemokine receptor 1 (CX3CR1) pathway has been identified to play an essential role in the chemotaxis of microglia, leukocyte trafficking and microglia/macrophage recruitment. It has also been shown to be important in the regulation of the inflammatory response in the early phase after experimental stroke. The present study was performed to investigate if CX3CR1 de

In this study, a computational model has been developed to predict condensation heat transfer between vertical parallel plates. Transient simulations of filmwise condensation in a small two-dimensional parallel plate passage are performed. The Volume of Fluid (VOF) method is used to track the vapor liquid interface. The Geometric Reconstruction Scheme, which is a Piecewise Linear Interface Calcula

The 2012–14 reform of the Belgian state has deeeply transformed its Senate. Not only does the reform reduce the legislative powers of the Belgian upper chamber, but it also alters its composition. The former appointment of Senators based on a system of direct and community-based election is replaced by a system of indirect and mixed regional and community-based designation. This article presents t

Examensarbetets titel: Nya föreskrifter om utbildning och prov - En deprofessionalisering av revisorsyrket? Seminariedatum: 2019/01/17 Ämne/kurs: FEKH69, Examensarbete i redovisning på kandidatnivå, 15 högskolepoäng (HP) Författare: Juliette Johlin, Izabella Jonsson, Johanna Levin Handledare: Karin Jonnergård Fem nyckelord: revisorsprofession, auktoriserad revisor, professionalism, utbildningskravTitle: New regulations in education and exams – A change in the professionalism of auditors? Seminar date: 17/01/2019 Course: FEKH69, Degree Project Undergraduate level, Business Administration, Undergraduate level, 15 University Credits Points (UPC) Authors: Juliette Johlin, Izabella Jonsson, Johanna Levin Advisor: Karin Jonnergård Key words: Professions, Certified public accountant (CPA), profes

Sammanfattning “Bemanning” är idag ett inarbetat begrepp som innebär att ett bemanningsföretag anställer personal för att hyra ut dessa till att utföra arbete hos ett kundföretag. Det betyder att det normala anställningsförhållandet mellan en arbetsgivare och en arbetstagare får en tredje involverad part. Branschen har växt sedan början av 90-talet och har kommit att bli en allt mer etablerad del Abstract The staffing agency is today a well-known concept. Staffing agencies hire employees in order to rent them out to companies to fill vacancies on the market. This means that the traditional employment relationship between the employer and the employee now often involves a third party. The industry has grown since the early nineties and has become an established part of the labour market due