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Validation Of An Artificial Intelligence System To Assess Postural Orientation During A Single-Leg Squat

Alteration in postural orientation (i.e., the ability to align body segments in relation to each other) can occur due to pain or injury and is suggested to be a risk factor for traumatic knee injuries and early onset and progression of knee osteoarthritis. However, clinical and biomechanical assessment of postural orientation is time-consuming, thus new and faster methods are needed in order to be

The relationship between blood pressure and risk of renal cell carcinoma

BACKGROUND: The relation between blood pressure and kidney cancer risk is well established but complex and different study designs have reported discrepant findings on the relative importance of diastolic blood pressure (DBP) and systolic blood pressure (SBP). In this study, we sought to describe the temporal relation between diastolic and SBP with renal cell carcinoma (RCC) risk in detail.METHODS

Machine learning for early prediction of acute myocardial infarction or death in acute chest pain patients using electrocardiogram and blood tests at presentation

Aims: In the present study, we aimed to evaluate the performance of machine learning (ML) models for identification of acute myocardial infarction (AMI) or death within 30 days among emergency department (ED) chest pain patients. Methods and results: Using data from 9519 consecutive ED chest pain patients, we created ML models based on logistic regression or artificial neural networks. Model input

MafB-dependent neurotransmitter signaling promotes β cell migration in the developing pancreas

Hormone secretion from pancreatic islets is essential for glucose homeostasis and loss or dysfunction of islet cells is a hallmark of type 2 diabetes. Maf transcription factors are critical for establishing and maintaining adult endocrine cell function. However, during pancreas development, MafB is not only expressed in insulin- and glucagon-producing cells, but also Neurog3+ endocrine progenitor

Exploring the Role of Globular Domain Locations on an Intrinsically Disordered Region of p53 : A Molecular Dynamics Investigation

The pre-tetramerization loop (PTL) of the human tumor suppressor protein p53 is an intrinsically disordered region (IDR) necessary for the tetramerization process, and its flexibility contributes to the essential conformational changes needed. Although the IDR can be accurately simulated in the traditional manner of molecular dynamics (MD) with the end-to-end distance (EEdist) unhindered, we sough

Diabetic status and the performances of creatinine- and cystatin C–based eGFR equations

Background. The estimation of glomerular filtration rate (GFR) is one tool to detect renal disease. The most used biomarker remains serum creatinine and the European Kidney Function Consortium (EKFCcrea ) equation is the most validated in Europe. More recently, cystatin C has been proposed as a biomarker. We studied the performances of the EKFC equations in a large cohort of subjects according to

In Vivo Photopolymerization : Achieving Detailed Conducting Patterns for Bioelectronics

Bioelectronics holds great potential as therapeutics, but introducing conductive structures within the body poses great challenges. While implanted rigid and substrate-bound electrodes often result in inflammation and scarring in vivo, they outperform the in situ-formed, more biocompatible electrodes by providing superior control over electrode geometry. For example, one of the most researched met

Synovial fibroblasts from children with oligoarticular juvenile idiopathic arthritis induce migration and prolong viability of neutrophils

Introduction: Little is known of the processes that trigger neutrophil activation in the joint of patients with oligoarticular juvenile idiopathic arthritis (oJIA), and if synovial fibroblasts (S-Fib) play an important role in the activation. Therefore, we aimed to investigate whether S-Fib derived from oJIA patients drive neutrophil activation. Methods: Synovial fluid (SF) was collected from pati

Clustering Methods for the Characterization of Synchrotron Radiation X-Ray Fluorescence Images of Human Carotid Atherosclerotic Plaque

This study employs computational algorithms to automatically identify and classify features in X-Ray fluorescence (XRF) microscopy images. Principal component analysis (PCA) and unsupervised machine learning algorithms, such as Gaussian mixture (GM) clustering, are implemented to label features on a collection of XRF maps of human atherosclerotic plaque samples. The investigation involves the hard

The impact of disease activity and interferon-α on the nervous system in systemic lupus erythematosus

BACKGROUND: Systemic lupus erythematosus (SLE) patients, with or without neuropsychiatric SLE (NPSLE), exhibit greater neuronal impairment compared to healthy individuals in terms of neuronal damage, magnet resonance imaging (MRI) changes and cognitive dysfunction. Interferon (IFN)-α is a key immunopathogenic driver of SLE, being persistently overexpressed in the majority of patients. This longitu

Renovera för hela livet. Det är inte bara en fråga för fastighetsägare.

Bostadskrisen slår mot alla generationer – men lösningarna måste vara långsiktiga och inkludera de behov äldre människor har. Det skriver fyra forskare som är verksamma vid institutionen för hälsovetenskaper vid Lunds universitet och tillhörforskningscentret CASE, Centre for Ageing and Supportive Environments.

Development of Photoacoustic Imaging Techniques Towards Clinical Translation

This thesis encompasses an introductory part and five papers related to developing techniques and phantoms required for the further growth of photoacoustic imaging (PAI). In PAI, images are created by detecting acoustic waves followed by the absorption of laser light, enabling high spatial resolution while maintaining high optical contrast. Due to the distinct absorption patterns of various chromo

Exhaustion Doctrine: Close to the Ultimate Aim of Copyright

The exhaustion doctrine (also known in some jurisdictions as the ''first sale doctrine See U.S. Copyright Code Section 109(a)'') is one of the basic rules of intellectual property (IP) system, and is applied to many IP rights, from copyright to trademark. The term ''exhaustion'' or ''first sale'' describes the concept of this rule, where, after the &

United States extraterritorial application of economic sanctions and the new international sanctions against Iran

Economic sanctions are defined as the exercise of pressure by one state to produce a change in the political behaviour of another state. Traditional economic sanctions are directed at the entire population of a state whilst targeted sanctions are directed at a state’s individuals. This thesis discusses the application of economic sanctions against Iran by the UN, the EU and the United States. Econ

Bolagsskatt - hur svenska företags effektiva skattesats kan påverkas

Vid en diskussion om nivån på den svenska bolagsskatten är det av stor vikt att avgöra huruvida diskussionen rör den nominella eller den effektiva skattesatsen. Den nominella skattesatsen uppgår till 28 procent och återfinns i 65 kap. 14 § IL. Den effektiva skattesatsen är däremot inte given utan kan i viss utsträckning påverkas, eftersom den bestäms genom att dividera skatt på årets resultat med

Assessing soil microbial tolerance to salt

Salinisation is a global issue which leads to desertification and soil degradation and exposure to salt is also known to inhibit microbial activity and plant growth. This study was conducted to determine the influence of salinity on microbial activity of a non- saline soil. By using Salt Induced Community Tolerance (SICT) concept I found that microbial community tolerance to salt can be induced in

Första delsvaret på frågan varför fetmaoperation botar diabetes – Vetenskap och Hälsa

Första delsvaret på frågan varför fetmaoperation botar diabetes – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Första delsvaret på frågan varför fetmaoperation botar diabetes 2013-05-02 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Nils Wierup. Foto: Katr

https://www.vetenskaphalsa.se/forsta-delsvaret-pa-fragan-varfor-fetmaoperation-botar-diabetes/ - 2025-12-12