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Background: Ocrelizumab is a humanized anti-CD20 antibody with increased antibody-dependent cellular cytotoxicity compared with rituximab. This phase I/II study evaluated its safety and efficacy in patients with relapsed/refractory follicular lymphoma (FL) after prior rituximab therapy. Design and methods: Forty-seven patients were treated in three dose cohorts and received eight infusions every 3

Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that

Primary hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disorder associated with autosomal recessive variants in genes required for perforin-mediated lymphocyte cytotoxicity. A rapid diagnosis is crucial for successful treatment. Although defective cytotoxic T lymphocyte (CTL) function causes pathogenesis, quantification of natural killer (NK)–cell exocytosis triggered by K562 targe

Streptococcus pyogenes (Group A streptococcus; GAS) is an important human pathogen responsible for mild to severe, life-threatening infections. GAS expresses a wide range of virulence factors, including the M family proteins. The M proteins allow the bacteria to evade parts of the human immune defenses by triggering the formation of a dense coat of plasma proteins surrounding the bacteria, includi

This study explores the use of manganese ore, iron-carbon particles (Fe-C), and gravel as anode fillers in electroactive constructed wetlands (ECWs) to treat wastewater containing pharmaceuticals and personal care products (PPCPs) including ciprofloxacin (CIP), ofloxacin (OFL), and naproxen (NPX), while also assessing bioelectricity production. Although the presence of PPCPs reduced pollutant remo

INTRODUCTION: Synaptic dysfunction and loss are pathological hallmarks of neurodegenerative diseases. Neuronal pentraxin 2 (NPTX2), a presynaptic protein involved in synaptic plasticity, has been linked to cognitive decline in Alzheimer's disease (AD) and other neurodegenerative disorders. METHODS: We developed and validated a novel single molecule array (Simoa) for NPTX2 in cerebrospinal fluid, w

Acousmatic Concerts at IAC PROGRAMME 22–26 APRIL 2026 IAC.LU.SE Scan the QR code for detailed programme and artist bios! Wednesday, 22 April 17:00 & 19:00 ELIDE SULSENTI: Tundo, Sdraulig (Black Room) Performance with cello and headphones. Limited to 15 listeners per concert! Matteo Tundo – Cuoio (for cello and electronics) Charlie Sdraulig – Arc (for cello and electronics) Total duration: ca. 30 m

https://www.iac.lu.se/sites/iac.lu.se/files/2026-05/Intonal_2026_broschyr_A5_FINAL.pdf - 2026-05-14

A series of homoleptic bis(tridentate) [Ru-(L)(2)](2+) (1, 3) and heteroleptic [Ru(L)(dqp)](2+) complexes (2, 4) [L = dqxp (1, 2) or dNinp (3, 4); dqxp = 2,6-di(quinoxalin-5-yl)pyridine, dNinp = 2,6-di(N-7-azaindol-1-yl)pyridine, dqp = 2,6-di(quinolin-8-yl)pyridine) was prepared and in the case of 2 and 4 structurally characterized. The presence of dqxp and dNinp in 1-4 result in anodically shifte

Abstract in French:Cet article contribue à la recherche sur la géopolitique urbaine par une théorisation « extrospective » du pouvoir local sur la scène internationale – c’est-à-dire une orientation du développement socio-économique qui encourage tant la concurrence que la coopération entre les entités métropolitaines au-delà des frontières de l’État-nation. Empiriquement, l’article se concentre sThis article contributes to research on urban geopolitics through an extrospective theorization of local territorial influence on the international stage. Empirically, the article focuses on a comparative study of extrospective development initiatives from Malaga (Spain) and Mazara del Vallo (Sicily) that have recently emerged in response to the effects of the Great Recession. We examine the symbo

In this study, we report on reactive large-eddy simulations (LESs) of flow and combustion in the U.S. Air Force Research Laboratory Research Cell 19 cavity-based scramjet combustor. This case involves the combustion of ethylene that is injected into a cavity. It has previously been studied experimentally with multiple techniques, including particle image velocimetry, hyperspectral imagining, and l

Popular Abstract in Swedish Trots ny fordonsteknik så har koldioxidutsläppen ökat med nästan 40% i Europa sedan 1990-talet. Detta beror främst på en tilltagande transport på våra vägar. Drivmedel som används inom transportsektorn är nästan uteslutande diesel och bensin, vilka härstammar från fossila bränslen. För att hantera konsekvenserna av transportfordons miljöpåverkan så blir lagstiftningen p

Researcher Contact details Email: hebatalla [dot] taha [at] svet [dot] lu [dot] seOrganisation Centre for Advanced Middle Eastern Studies (CMES) Service point: 18 WebpageHebatalla Tahas profile in Lund University research portalOther affiliations Associate senior lecturer Department of Political Science Member of Strategic Research Area MECW: The Middle East in the Contemporary WorldPolitical Scie

https://www.svet.lu.se/en/hebatalla-taha - 2026-05-14