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Combinatorial Methodology. Screening for affinity specific ligands to biological and artificial receptors.

Combinatorial screening methodology has been employed to select new affinity specific ligands to bilogical and artificial receptors. The screening methodology, in particular screening of combinatorial phage display peptide libraries against target molecules differing in function and shape, is focused upon. A linear combinatorial phage display hexapeptide library has been used to select novel pept

ICOS-ligand triggering impairs osteoclast differentiation and function in vitro and in vivo

Osteoblasts, osteocytes, and osteoclasts (OCs) are involved in the bone production and resorption, which are crucial in bone homeostasis. OC hyperactivation plays a role in the exaggerated bone resorption of diseases such as osteoporosis, rheumatoid arthritis, and osteolytic tumor metastases. This work stems from the finding that OCs can express B7h (ICOS-Ligand), which is the ligand of the ICOS T

Systemic sclerosis. Novel molecular and epidemiological features of disease.

Popular Abstract in Swedish Systemisk skleros (SSc) är en relativt ovanlig reumatologisk sjukdom som kan engagera många av kroppens organ. Sjukdomen kallas ibland också för sklerodermi. Typiskt för sjukdomen är att huden omvandlas till fibros och blir hård och stram över olika delar av kroppen. Typiskt för sjukdomen är också att drabbade patienter har försämrad funktion i sina blodkärl, framförallSystemic sclerosis (SSc) is a systemic rheumatic disease with significant mortality and morbidity. Different estimations of disease prevalence and incidence have been presented from various parts of the world. While lung involvement is a common cause of SSc-related death, a majority of SSc patients suffer from symptoms originating in the gastrointestinal (GI) tract. By combining data from a popu

µHDS system for desulfurization of logistic fuels for fuel cell applications

Bränsleceller är ett intressant alternativ till förbränningsmotorer då bränsleceller har en högre effektivitet, är miljövänligare samt tystare. Bränslen som diesel, bensin samt det undersökta bränslet Jet A1, innehåller olika svårreagerade svavelföreningar. Problemet med bränslena är att de har ett relativt högt svavelinnehåll. Svavelföreningarna riskerar att förgifta katalysatorerna i de nedströ

Bacteria-immunoglobulin-lymphocyte interactions--new aspects

Of 30 bacterial species tested 18 stimulated DNA synthesis in human blood lymphocytes. The maximum response was after 3-4 days of culture suggesting a mitogenic effect. This was confirmed by the induction of polyclonal antibody production shown by a plaque assay. Most bacterial species increased the DNA synthesis in B-enriched lymphocytes and unseparated lymphocytes but had negligible activity on

Utvc22 schedule autumn2017 updated 2017-08-10

BIDS UTVC22 Lectures and seminars 2017. Schedule 2017-08-10 Date Time Room Theme Activity Group Teacher Module 1: Course Introduction 1/11 10:15-12:00 111 Course introduction Intro 1/1 AF Issues in contemporary development: The quest for growth and the internationalization of development 3/11 10:15-12:00 111 The Elusive Quest for Growth Lec 1/1 PYA 8/11 10:15-12:00 111 The Elusive Quest for Growth

https://www.keg.lu.se/sites/keg.lu.se/files/utvc22_schedule_autumn2017_updated_2017-08-10.pdf - 2026-05-14

Utvc22 schedule autumn2017 updated 2017-05-12

BIDS UTVC22 Lectures and seminars 2017. Schedule 2017-05-12 Date Time Room Theme Activity Group Teacher Module 1: Course Introduction 1/11 10:15-12:00 111 Course introduction Intro 1/1 AF Issues in contemporary development: The quest for growth and the internationalization of development 3/11 10:15-12:00 111 The Elusive Quest for Growth Lec 1/1 PYA 8/11 10:15-12:00 111 The Elusive Quest for Growth

https://www.keg.lu.se/sites/keg.lu.se/files/utvc22_schedule_autumn2017_updated_2017-05-12.pdf - 2026-05-14

Cerege research centre 2017

NGEA51: Practical work Felix Martin Hofmann Summary of the internship in the Laboratoire National des Nucléides Cosmogéniques in Aix-en-Provence (France) Between the 6th November and the 22nd December 2017, I completed an internship in the Laboratoire des Nucléides Cosmogéniques within the CEREGE Geoscience Research Centre (Centre Européen de la Recherche et d’Enseignement des Geosciences de l’Env

https://www.nateko.lu.se/sv/sites/nateko.lu.se.sv/files/cerege_research_centre_2017.pdf - 2026-05-14

Ngea51 internship summary felix martin hofmann

NGEA51: Practical work Felix Martin Hofmann Summary of the internship in the “Laboratoire National des Nucléides Cosmogéniques” (LN2C) in Aix-en-Provence (France) Between the 6th November and the 22nd December 2017, I completed an internship in the “Laboratoire National des Nucléides Cosmogéniques” (LN2C) within the Geoscience Research Centre “Centre Européen de la Recherche et d’Enseignement des

https://www.nateko.lu.se/sv/sites/nateko.lu.se.sv/files/ngea51_internship_summary_felix_martin_hofmann.pdf - 2026-05-14

Effects of muscular dystrophy, exercise and blocking activin receptor IIB ligands on the unfolded protein response and oxidative stress

Protein homeostasis in cells, proteostasis, is maintained through several integrated processes and pathways and its dysregulation may mediate pathology in many diseases including Duchenne muscular dystrophy (DMD). Oxidative stress, heat shock proteins, endoplasmic reticulum (ER) stress and its response, i.e. unfolded protein response (UPR), play key roles in proteostasis but their involvement in t