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Factor H–IgG chimeric proteins as a therapeutic approach against the gram-positive bacterial pathogen Streptococcus pyogenes

Bacteria can cause life-threatening infections, such as pneumonia, meningitis, or sepsis. Antibiotic therapy is a mainstay of treatment, although antimicrobial resistance has drastically increased over the years. Unfortunately, safe and effective vaccines against most pathogens have not yet been approved, and thus developing alternative treatments is important. We analyzed the efficiency of factor

CCL25/CCR9 promotes the induction and function of CD103 on intestinal intraepithelial lymphocytes.

The integrin CD103 and the chemokine receptor CCR9 are co-expressed on small intestinal CD8+ intraepithelial lymphocytes (IEL), naïve murine CD8+ T cells and by a small population of effector/memory CD8+ T cells, indicating a potential role for CCR9 in regulating CD103 expression and function. Here, we demonstrate that CD103, in contrast to CCR9, is down-regulated on CD8+ T cells following their a

MEDI-563, a humanized anti-IL-5 receptor alpha mAb with enhanced antibody-dependent cell-mediated cytotoxicity function

Background: Peripheral blood eosinophilia and lung mucosal eosinophil infiltration are hallmarks of bronchial asthma. IL-5 is a critical cytokine for eosinophil maturation, survival, and mobilization. Attempts to target eosinophils for the treatment of asthma by means of IL-5 neutralization have only resulted in partial removal of airway eosinophils, and this warrants the development of more effec

176 You Et Al. Predictors Of Transitions From GADA As The Initial Autoantibody To Multiple Autoantib

Predictors of Transitions From GADA as the Initial Autoantibody to Multiple Autoantibodies of Type 1 Diabetes in Children at Risk by a Dynamic Prediction Model - 10022025_679_176_MP280_You_Ped Diab_2025.pdf PdrdYpbg :pshbkd Mpdchbsnpr ne SpZmrhshnmr Dpnl F9C9 Zr sgd HmhshZk 9tsnZmshancw sn Ltkshokd 9tsnZmshanchdr ne Swod 0 ChZadsdr hm Bghkcpdm Zs Phri aw Z CwmZlhb Mpdchbshnm Lncdk Kt Wnt0 DZkZrshm

https://www.teddy.lu.se/sites/teddy.lu.se/files/2025-11/176%20You%20et%20al.%20Predictors%20of%20Transitions%20From%20GADA%20as%20the%20Initial%20Autoantibody%20to%20Multiple%20Autoantibodies%20of%20Type%201%20Diabetes%20in%20Children%20at%20Risk%20by%20a%20Dynamic%20Prediction%20Model%20-%20Ped%20Diab_2025.pdf - 2026-05-10

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XX c'est moi. J'ai blond cheveux et je suis 188 centimètres. J'ai seize ans et j'habite à Malmö de puis douze ans. Avant j'habite à XX. Mais quand je suis quatre ans nous installons à Malmö dans une grande maison avec ma mère, mon père et ma soeur. Maintenant j' habite avec ma mère et ma soeur dans un apartement. Ma mére s'appelle MM et ma soeur s'applle EE. EE est en France maintenant pour étudie

https://projekt.ht.lu.se/fileadmin/user_upload/project/cefle/textes/le_sous-corpus_longitudinal/caesar/Texte_4.txt - 2026-05-09

BspK, a serine protease from the predatory bacterium Bdellovibrio bacteriovorus with utility for analysis of therapeutic antibodies

The development of therapeutic and diagnostic antibodies is a rapidly growing field of research, being the fastest expanding group of products on the pharmaceutical market, and appropriate quality controls are crucial for their application. We have identified and characterized the serine protease termed BspK (Bdellovibrio serine protease K) from Bdellovibrio bacteriovorus and here show its activit

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https://goteborgonline-my.sharepoint.com/personal/peter_jonsson_educ_goteborg_se/Documents/C%20e%20n%20t%20r%20a%20l%20a%20%20%20S%20a%20c%20o%20r%20å%20d%20e%20t%20%20%20i%20%20%20G%20ö%20t%20e%20b%20o%20r%20g%20s%20%20%20S%20t%20a%20d/AU/SKOT/C%20E%20N%20T%20R%20A%20L%20A%20%20%20S%20A%20C%20O%20R%20Å%20D%20E%20T%20%20%20I%20N%20F%20O%20R%20M%20E%20R%20A%20R/December%202024/www.saco.se/goteborg

https://www.saco.se/globalassets/lokala-akademikerforeningar/kommun-och-region/goteborgs-stad/dokument/centrala-sacoradet-informerar/april-2025_centrala-sacoradet-informerar.pdf - 2026-05-10

Retirement return migration from Sweden

Abstract in Spanish Este estudio aborda el movimiento de retorno entre los inmigrantes establecidos en Suecia y que tienen entre 51 y 80 años de edad. Una cuestión importante se refiere a la repercusión de la jubilación en la migración de retorno. Algunas circunstancias vinculadas con el abandono del mercado laboral sugieren una mayor tendencia al retorno, por ejemplo la transición del cobro de unThis study deals with return migration among immigrants in Sweden who are between 51 and 80 years old. An important question regards the impact of retirement on return migration. Some circumstances connected to the withdrawal from the labour market suggest an increased propensity to return, such as the transition from a wage income to a pension, which weakens the link between place of residence an

Functional C1-inhibitor diagnostics in hereditary angioedema: Assay evaluation and recommendations

Hereditary angioedema (HAE) is an autosomal dominant disease characterized by recurrent episodes of potentially life-threatening angioedema. The most widespread underlying genetic deficiency is a heterozygous deficiency of the serine protease inhibitor Cl esterase inhibitor (C1-Inh). In addition to low C4 levels, the most important laboratory parameter for correct diagnosis of HAE or angioedema du

Microscopy of stained smears of vaginal secretion in the diagnosis of recurrent vulvovaginal candidosis

This study was undertaken to determine the value of stained smears from the vaginal introitus and the posterior vaginal fornix for detection of candida morphotypes in the diagnosis of recurrent vulvovaginal candidosis (RVVC) in cases with an assumed novel attack of the condition, and to compare the value of microscopy of such smears in relation to candida culture, vaginal pH-determinations and leu

Influence of Maturity on Creep of High Performance Concrete.

This article outlines an experimental and numerical study of basic creep in High Performance Concrete. About 100 cylinders (studies of creep and shrinkage) and 400 cubes (for studies of hydration, internal relative humidity, and strength) were tested. The ambient climate was held constant at 20°C. One concrete was studied at other temperatures between -20°C and 60°C. Analyses were carried out of q