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Plasma and cerebrospinal fluid neurofilament light concentrations reflect neuronal damage in systemic lupus Erythematosus

BACKGROUND: Neuronal damage in systemic lupus erythematosus (SLE) is common, but the extent and mechanisms are unclear. Neurofilament light (NfL) concentrations rise in plasma and cerebrospinal fluid (CSF) during neuronal damage in various neurological disorders. In this cross-sectional study, plasma and CSF concentrations of NfL were explored as a marker of neuronal damage in SLE.METHODS: Seventy

Mos halvtidskontroll - variabellista 2019-02-20

MOS Variabellista inkl frekvenser - Halvtidskontroll (2018-06-13) Sida 1 av 50 Nr Name Format Variable label File Checked #B #BB Deltagare 1 lopnrMOS Numeric Löpnummer vid MOS baslinjeundersökning (Numerisk) MOS_Deltagare_halvtid.savAD 1326 1321 2 lopnrMOS_str8 String Löpnummer vid MOS baslinjeundersökning (Sträng, utan mellanstreck)MOS_Deltagare_halvtid.savAD 1326 1321 3 lopnrMOS_str9 String Löpn

https://www.malmo-kohorter.lu.se/sites/malmo-kohorter.lu.se/files/2024-03/mos_halvtidskontroll_-_variabellista_2019-02-20.pdf - 2026-05-20

Comparison of plasma ALZpath p-Tau217 with Lilly p-Tau217 and p-Tau181 in a neuropathological cohort

There is an urgent need for accurate and validated methods to measure plasma phosphorylated tau (p-Tau) biomarkers in Alzheimer’s disease (AD). In this study, we compared the performance of new commercially available plasma p-Tau217 assay developed by ALZpath to other established p-Tau assays in an autopsy-confirmed sample. We included 72 participants from the Arizona Study of Aging and Neurodegen

Vaccine effectiveness against influenza A in older adults and the effect of chronic conditions : results from the I-MOVE and VEBIS multicentre European hospital case–control studies, 2015/16–2023/24

Background: The Influenza – Monitoring Vaccine Effectiveness in Europe (I-MOVE/I-MOVE+) and Vaccine Effectiveness, Burden and Impact Studies (VEBIS) hospital networks have conducted seasonal multicentre, test-negative, case–control studies in Europe to measure influenza vaccine effectiveness (IVE) since 2015/16. We measured the effect of chronic conditions on VE of influenza A subtypes among older

Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

Background: Disorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Global Burden of Disease, Injuries, and Risk Factor Study estimated the burden of 15 neurological conditions in 2015 and 2016, but these analyses did not i

Can 177Lu-DOTATATE Kidney Absorbed Doses be Predicted from Pretherapy SSTR PET? Findings from Multicenter Data

Before performing 177Lu-DOTATATE therapy for neuroendocrine tumors, somatostatin receptor (SSTR) PET imaging is currently used to confirm sufficient tumor SSTR expression, but it also has potential to be used to personalize treatment by predicting absorbed doses to critical organs. This study aims to validate the predictive capability of SSTR PET in anticipating renal absorbed dose in the first cy

Alpha-synuclein seed amplification assay longitudinal outcomes in Lewy body disease spectrum

Evidence from neuropathological cohorts indicates that a CSF α-synuclein (α-syn) seed amplification assay (SAA) might provide quantitative kinetic parameters correlating with α-syn pathology burden in patients with Lewy body disease (LBD). Studies are needed to assess their longitudinal trend during the presymptomatic and clinical disease phases and their correlation with measures of disease progr

Adverse Pregnancy Outcomes and Long-Term Risk of Atrial Fibrillation

Importance Women with adverse pregnancy outcomes have higher subsequent cardiovascular risks, but their long-term risk of atrial fibrillation (AF) and potential causality are unclear. A better understanding of such risks is needed to identify women with high risk early in life and guide interventions to prevent AF and its complications. Objective To determine long-term risks of AF associated with

A Genetic Risk Adoption Design for Psychiatric and Substance Use Disorders

Importance: Traditional adoption studies examine disorder-to-disorder parent-offspring transmission. The role of parental genetic risk in offspring disorder transmission can capture indirect genetic effects from parental genotype to parental phenotype to offspring risk. Objective: To assess the relative importance of genetic and rearing effects from paternal family genetic risk scores (FGRSs) in 3

Pulmonary Nodule Prevalence at CT in Middle-Aged Participants from the Swedish CArdioPulmonary bioImage Study (SCAPIS)

Background Pulmonary nodules (PNs) are clinically challenging because differentiation between benign and malignant PNs is not possible at CT detection; recurring CT examinations and invasive procedures are often required in PN follow-up. Purpose To investigate PN prevalence in a middle-aged population and the risk factors associated with these nodules. Materials and Methods In this secondary analy

Plasma pTau 217/β-amyloid 1–42 ratio for enhanced accuracy and reduced uncertainty in detecting amyloid pathology

Blood biomarkers have the potential to revolutionize Alzheimer's disease diagnosis, offering advantages over CSF and PET due to their accessibility, scalability and cost-effectiveness. This study evaluated the effectiveness of individual plasma biomarkers, such as phosphorylated Tau (pTau) 217, as well as biomarker combinations, with a focus on the pTau 217/β-Amyloid (Aβ) 1–42 ratio to predict amy

Association Between Dietary Habits in Midlife With Dementia Incidence Over a 20-Year Period

BACKGROUND AND OBJECTIVES: Dementia cases are expected to triple during the next 30 years, highlighting the importance of finding modifiable risk factors for dementia. The aim of this study is to investigate whether adherence to conventional dietary recommendations or to a modified Mediterranean diet are associated with subsequent lower risk of developing all-cause dementia, Alzheimer's disease (A

Association of Sleep Duration with All- And Major-Cause Mortality among Adults in Japan, China, Singapore, and Korea

Importance: The association between long sleep duration and mortality appears stronger in East Asian populations than in North American or European populations. Objectives: To assess the sex-specific association between sleep duration and all-cause and major-cause mortality in a pooled longitudinal cohort and to stratify the association by age and body mass index. Design, Setting, and Participants

Mesenchymal heterogeneity in the adult human lung

The human lung is a complex tissue consisting of a heterogeneous mix of different structures and cells, each which a specific role that together contribute to the primary function of the organ: the gas exchange. Different mesenchymal cells populate the interstitial areas around airways and blood vessels and form the connective tissue together with the extracellular matrix. Fibroblasts constitute o

Lunds-universitets-magasin-8-2011

Lunds universitets magasin | Nr 8 | 2011 sätt fart på lärlusten! Mindre rörigt med samlade bibliotek LTH-studenter bakom världspatent 2 LUM nr 8 | 2011 heliga hjältar LUM nr 8 | 2011 3 Judiska superhjältar i Jewish Hero Corps... islam-inspirerade figu- rer som strider mot skurkar i den populära serien The 99... ett vimmel av skäggiga asagudar, änglar och demoner, och en katolsk seriepåve med namne

https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-8-2011.pdf - 2026-05-20

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Light verb objects Fredrik Heinat, University of Gothenburg This paper is about the status of the post verbal NP in light verb constructions such as (1a) and (1b). The reason to examine the object status of these NPs is that they have been claimed to have a different behaviour than ‘ordinary’ direct objects. In addition to light verb objects, cognate objects, such as in (1c) and (1d), have been cl

https://konferens.ht.lu.se/fileadmin/_migrated/content_uploads/11.Heinat-GiF-2009_01.pdf - 2026-05-16

Writing in English at University: A Guide for Second Language Writers

Writing in English at University: A Guide for Second Language Writers Writing in English at University: A Guide for Second Language Writers Published 25 September 2020 This new textbook is for anyone who wishes to learn more about academic writing in English. Writing in English at University: A Guide for Second Language Writers is a textbook designed to accompany the MOOC Writing in English at Uni

https://www.sol.lu.se/en/article/writing-in-english-at-university-a-guide-for-second-language-writers/ - 2026-05-18