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OBJECTIVE: To investigate the possible role of FCGR2A 519A>G and FCGR3A 559A>C functional polymorphisms in the genetic predisposition to susceptibility to systemic sclerosis (SSc) or clinical phenotype. METHODS: A total of 1566 patients with SSc and 2271 geographically matched controls were included in our study. We analyzed the genotype and allele frequencies of the FCGR2A 519A>G and FCGR3A 559A>

In a previous study we presented data indicating that the expanded population of CD4(-)CD8(-) (DN) alphabeta T cells in TCRalpha-chain-transgenic mice was partially if not entirely derived from gammadelta T cell lineage cells. The development of both gammadelta T cells and DN alphabeta T cells is poorly understood; therefore, we thought it would be important to identify the immediate precursors of

Protein kinase C (PKC) plays a prominent role in immune signaling, and the paradigms for isoform selective signaling are beginning to be elucidated. Real-time microscopy was combined with molecular and biochemical approaches to demonstrate a role for PKC-epsilon in Fcgamma receptor (FcgammaR)-dependent phagocytosis. RAW 264.7 macrophages were transfected with GFP-conjugated PKC isoforms, and GFP m

Immunoglobulin G (IgG) glycosylation modulates antibody activity and represents a major source of heterogeneity within antibody preparations. Depending on their glycosylation pattern, individual IgG glycovariants present in recombinant antibody preparations may trigger effects ranging from enhanced pro-inflammatory activity to increased anti-inflammatory activity. In contrast, reduction of IgG gly

Current hemophilia B treatment guidelines recommend routine prophylaxis with factor IX (FIX) replacement products, tailored to maintain plasma activity at levels that will prevent bleeds. However, plasma FIX activity may not be the primary determinant or best indicator of hemostatic efficacy due to its extravascular distribution. FIX replacement therapy has evolved to include extended half-life (E

Room Temperature Ionic Liquids (RTILs) are organic salts that melt below 100 degrees Celsius. The advantages of RTILs, such as high ionic concentrations and low melting points, promote several potential applications. For instance, RTILs could be utilized in manufacturing energy storage devices, and as efficient solvents. In this work, an Asymmetric Restricted Primitive Model (ARPM) of electrolyte

https://www.ehl.lu.se/sites/ehl.lu.se/files/2025-04/Tentaschema%20VT%202025%20%20februari%20-%20augusti%202025%20extern%20hemsida%202025-04-03.pdf - 2026-05-20

https://www.ehl.lu.se/sites/ehl.lu.se/files/2025-02/Tentaschema%20VT%202025%20%20februari%20-%20augusti%202025%20extern%20hemsida%202025-02-11.pdf - 2026-05-20

https://www.ehl.lu.se/sites/ehl.lu.se/files/2025-05/Tentaschema%20VT%202025%20%20februari%20-%20augusti%202025%20extern%20hemsida%202025-05-13.pdf - 2026-05-20

This thesis discusses the development of Product Category Rule (PCR) for semiconductor Back-End (BE) processes. While Life Cycle Assessment (LCA) are common practice in the industry, there is currently no PCR specifically for BE processes, which creates inconsistent reporting of emissions. This thesis provides a meta-analysis of allocation methodologies for semiconductor packaging. The meta-analys

Human financial decisions are known to deviate from ‘rational’, particularly under uncertainty and if time delays are involved. In the Nobel-winning prospect theory, Tversky and Kahneman showed that deviations from rational behavior were not only robust but also quite predictable, if considering average behavior in a population. They found that people consider gains and losses not in absolute term

LUNDS UNIVERSITET Tidplan HT2023 230201 HT23: 230828 – 240114 HT23 LUND HELSINGBORG Termin 1 SOPA12 HT23 (93 stud) SOCIALT ARBETE SOM ÄMNE OCH PROFESSION (30 hp) Mån 28/8 – Sön 14/1 (fre 12/1) HT23 (66 stud) SOCIALT ARBETE SOM ÄMNE OCH PROFESSION (30 hp) Mån 28/8 – Sön 14/1 (fre 12/1) Termin 2 SOPB21 VT23 (90 stud) SAMHÄLLSVETENSKAP OCH SOCIALT ARBETE (30 hp) Mån 28/8 – Sön 14/1 (fre 12/1)) VT23 (

https://www.soch.lu.se/internt/sites/soch.lu.se.internt/files/2023-02/Tidplan%20HT23.pdf - 2026-05-20

The reliable operation of nuclear reactors is contingent upon precise control mechanisms for critical components, such as the head circulation pumps. This master thesis investigates an innovative approach to address the ramp-down speed of these pumps during external electrical grid failures by exploring the application of a supercapacitor group. Presently, the existing solution relies on a fly-whe

Hip fractures can be predicted using numerical models -You probably know at least one older person who broke their hip. Hip fractures most often affect older people and it is both painful, takes time to heal and is expensive for the society. If there was a way to predict and prevent fractures, a lot of suffering, time and money could be saved.-