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We present free energy estimates of nine 3-amidinobenzyl-1H-indole-2-carboxamide inhibitors of factor Xa. Using alchemical thermodynamic integration (TI) calculations, we estimate the difference in binding free energies with high accuracy and precision, except for mutations involving one of the amidinobenzyl rings. Crystal studies show that the inhibitors may bind in two distinct conformations, an
PowerPoint-presentation ALF - Tilldelningsberäkning Prioriteringskommittén gör en bedömning av ansökningarna om ALF-medel ur vetenskaplig synvinkel och sätter poäng på varje projekt. ALF beredningsgrupp bestämmer därefter hur mycket totala ALF projektmedel som ska avsättas, för år 2021 är det 209 Mkr. Själva fördelningen av ALF-projektmedel sker separat för två kostnadsslag; lokalkostnader och övr
Instruction and Exemple Instruction and example Enter data in cell on sheet Summary annual time. On the sheet for single months, enter acronym, work package and number of hours in areas marked with an ellipse in example, Other activities and absence is optional: Timesheet, Lund University - H2020 and Horizon Europe Employee: Researcher Typ of personnel: Senior Staff Beneficiary: Lund University Ac
Instruction and Exemple Instruction and example Enter data in cell on sheet Summary annual time. On the sheet for single months, enter acronym, work package and number of hours in areas marked with an ellipse in example, Other activities and absence is optional: Timesheet, Lund University - H2020 and Horizon Europe Employee: Researcher Typ of personnel: Senior Staff Beneficiary: Lund University Ac
Instruction and Exemple Instruction and example Enter data in cell on sheet Summary annual time. On the sheet for single months, enter acronym, work package and number of hours in areas marked with an ellipse in example, Other activities and absence is optional: Timesheet, Lund University - H2020 and Horizon Europe Employee: Researcher Typ of personnel: Senior Staff Beneficiary: Lund University Ac
Instruction and Exemple Instruction and example Enter data in cell on sheet Summary annual time. On the sheet for single months, enter acronym, work package and number of hours in areas marked with an ellipse in example, Other activities and absence is optional: Timesheet, Lund University - H2020 framework Employee: Researcher Typ of personnel: Senior Staff Beneficiary: Lund University Acronym: Ac
Instruction and Exemple Instruction and example Enter data in cell on sheet Summary annual time. On the sheet for single months, enter acronym, work package and number of hours in areas marked with an ellipse in example, Other activities and absence is optional: Timesheet, Lund University - H2020 framework Employee: Researcher Typ of personnel: Senior Staff Beneficiary: Lund University Acronym: Ac
Instruction and Exemple Instruction and example Enter data in cell on sheet Summary annual time. On the sheet for single months, enter acronym, work package and number of hours in areas marked with an ellipse in example, Other activities and absence is optional: Timesheet, Lund University - H2020 and Horizon Europe Employee: Researcher Typ of personnel: Senior Staff Beneficiary: Lund University Ac
Delegated decisions, enclosure 2 Travel Grants Applicant Amount (SEK) Activity Approved by Group affiliation Date of approval Lautaro Belfiori 15 209 AD/PD 2022. Barcelona, Spain, 15-20 March 2022 Angela Cenci Nilsson Maria Swanberg 2022-01-14 Gemma Salvadó 6 320 AD/PD 2022. Barcelona, Spain, 15-20 March 2022 Angela Cenci Nilsson Oskar Hansson 2022-01-14 Divya Bali 12 152 Course: Biomarkers in Neu
Purpose: To describe a new time-saving threshold visual field–testing strategy—Swedish Interactive Thresholding Algorithm (SITA) Faster, which is intended to replace SITA Fast—and to report on a clinical evaluation of this new strategy. Design: Description and validity analysis for modifications applied to SITA Fast. Methods: Five centers tested 1 eye of each of 126 glaucoma and glaucoma suspect p
Background: Sociodemographic and spatial disparities in incidence and mortality burden of colorectal cancer (CRC) are important to consider in the implementation of population screening, in order to achieve expected benefit and not increase health inequities. Analytic methods should be adapted to provide rational support for targeted interventions. Methods: CRC incidence rates by tumor stage (I-IV
Aims: Direct seeking of care at paediatric emergency departments may result from an inadequate awareness or a short supply of medical alternatives. We therefore evaluated the care-seeking patterns, availability of medical options and initial medical assessments – with overall reference to socioeconomic status – of parents at an urban paediatric emergency department in a Scandinavian country provid
Bakgrund Rörelserädsla grundar sig i hur en person upplever smärta och hur beteendet ändrar sig därefter. Det kan vara rädsla för fysisk aktivitet som då kan vara överdriven vilket kallas kinesiofobi. Om idrottaren skadar sig och utöver det utvecklar en rörelserädsla kan det påverka rehabiliteringen negativt. Fokus under rehabilitering av en idrottsskada är ofta kring den fysiska aspekten av skada
Bästa att var blå eller brun fjärilshona? Solen skiner och fjärilarna cirkulerar runt bland dina blommor. Har du någon gång funderat på varför fjärilar ofta är så färgrika? Här i Sverige har vi ca 400 dagfjärilar och en av de allra vanligaste är en liten men färgglad vid namn puktörneblåvinge (Polyommatus icarus). Hannarna är ljusblå med en stilren svart konturlinje och honorna varierar mellan atButterfly wing coloration and pattern are believed to be shaped by selection pressures arising from the needs of thermoregulation, as signals to conspecifics, or reducing predation risk. The Common Blue Butterfly (Polyommatus icarus) display a large variation in dorsal wing blueness among females. The gradual pattern of brown to blue wings varies between individual females and among populations in
Abstract Authors: Petra Henningsson & Maria Ley Title: “It is almost sarcasm to refer to a disability as an asset” - A qualitative study regarding the experience of being an adhd-diagnosed parent Supervisor: Johan Cronehed Assessor: Henriette Frees Esholdt Based on seven qualitative, semi-structured interviews with adhd-diagnosed parents, our aim is to deepen the knowledge regarding the posi
Lena WahlbergLegal Questions and Scientific AnswersOntological Differences and Epistemic Gaps in the Assessment of Casual RelationsDatum för disputation: fredagen den 3 december 2010Fakultetsopponent: professor Juha Karhu, Lapplands universitet, SverigeÄmne: allmän rättsläraAbstractA large number of legal rules create an obligation to prevent, repair or otherwise mitigate damage to human health or
https://www.jur.lu.se/forskning/disputationer/disputationer-2010 - 2026-05-17
Koordinator för Mötesplats Rydbergseminarier Kontaktinformation E-post: cord [dot] arnold [at] fysik [dot] lu [dot] se Telefon: +46 46 222 74 72 Mobil: +46 76 949 54 86Organisation Atomfysik Besöksadress: Professorsgatan 1, Lund Rumsnummer: A218 Hämtställe: 14 WebbplatsCord Arnolds profil i Lunds universitets forskningsportalAndra roller Medlem i Strategiskt forskningsområde NanoLund: Centre for N
https://www.fysik.lu.se/cord-arnold - 2026-05-17
Gustav Smith’s group Our researchHeart disease remains the leading cause of death globally. Major transitions in the spectrum of heart disease have occurred over time while the end-result, failure of the human heart to maintain sufficient output of blood for the demands of the body, referred to as heart failure, remains a common condition with high mortality rate. Notably, the importance of obesit
https://www.ludc.lu.se/research/molecular-epidemiology-and-cardiology - 2026-05-15
