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It has been proposed that hyaluronan-binding proteoglycans play an important role as guiding cues during neural crest (NC) cell migration, but their precise function has not been elucidated. In this study, we examine the distribution, structure and putative role of the two major hyaluronan-binding proteoglycans, PG-M/versicans and aggrecan, during the course of avian NC development. PG-M/versicans

Protein Microchip Array technology makes it possible to examine patterns of protein expressions and modifications. Current technologies such as two-dimensional get electrophoresis (2-DE) in combination with mass spectrometry allows the identification of biologically relevant proteins with high resolving power, but has also considerable limitations. Most spots observed in 2-DE are from high abundan

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Rapporten beskriver prototyper av kontinuerliga tvåfraktionsinsamlare för övervakning av partikulära luftföroreningar i arbetsmiljö som har konstruerats. En prototyp är personburen och ger möjligheter till insamling av två partikelstorleksfraktioner i 18 diskreta intervall. PIXE-metoden (analys med partikelinducerad röntgenstrålning) används för multielementanalys av de erhållna proven. Även med m

Quantitative magnetic resonance imaging (MRI)-based biomarkers, which capture physiological and functional tumor processes, were evaluated as imaging surrogates of early tumor response following chemoradiotherapy in glioma patients. A multiparametric extension of a voxel-based analysis, referred as the parametric response map (PRM), was applied to quantitative MRI maps to test the predictive poten

Abstract not available

Emergence of multiple-function products (MFPs) poses a variety of challenges and risks for achieving sustainable consumption and production as well as fair consumer society and universal design. We overviewed MFPs from these viewpoints and then, focusing on product standard as a means to create mechanisms to reduce environmental loads from products, elucidated advantages and limitation of five app

I Sverige finns ett antal företag som med stöd av offentlighetsprincipen samlar in personuppgifter ur allmänna handlingar och publicerar dessa i söktjänster på internet. Genom användning av söktjänsterna går det att skapa sig en utförlig bild av en viss individ. Söktjänsterna har i regel beviljats utgivningsbevis och omfattas därför av grundlagsskyddet i YGL. I Sverige har en vedertagen uppfattninIn Sweden, there are several companies that, relying on the principle of public access to official documents, gather personal data and publish this information in online search services. Through use of these services, it is possible to access a detailed profile of a specific individual. The search services have generally been granted a so-called certificate of publication and are consequently prot

Atelectasis formation can be reduced by positive endexpiratory pressure (PEEP), but resulting increases in intrathoracic pressure could affect circulation. We have earlier demonstrated that increased tidal volumes with larger apparatus dead space improves oxygenation and sevoflurane uptake. In the present study, we hypothesize that isocapnic ventilation with increased tidal volumes increases oxyge

Here, we describe the generation of an induced pluripotent stem cell (iPSC) line, from a male patient diagnosed with Parkinson's disease (PD). The patient carries a heterozygous variation p.A53T in the SNCA gene. Skin fibroblasts were reprogrammed using the non-integrating Sendai virus technology to deliver OCT3/4, SOX2, c-MYC and KLF4 factors. The generated iPSC line (CSC-32) preserved the mutati