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Assessment of cognition in ageing. Investigating internal validity, occurrence and reversion of Mild Cognitive Impairment. Data from the general population study “Good Aging in Skåne”

Bakgrund Med en snabbt växande äldre populationsgrupp kommer även andelen med kognitiva störningar, som demens, att växa. Det är således nödvändigt med forskning på kognition och åldrande. Denna avhandling, genom fyra delarbeten, redogör för testledareffekter vid kognitionsmätningar och hur yngre födelsekohorter (generationer) presterar bättre än äldre på kognitionstester. Den kommer även förklaraGiven a growing population of older adults and the common occurrence of natural as well as pathological cognitive decline, i.e. dementia, there is a need to better understand how to accurately measure and classify level of cognitive functioning. Both using multiple test administrators to collect cognitive data and what year the participant is born (birth cohort effects) can influence participants’

Climate Science for Policy? The knowledge politics of the IPCC after Copenhagen

Klimatförändringarna kommer att påverka ekosystem och samhällen över hela världen. Det är ett problem som kräver drastiska och omedelbara förändringar av vårt sätt att leva och av våra samhällsstrukturer, och därmed politiskt engagemang av aldrig tidigare skådat slag. Under de senaste 30 åren, sedan bildandet av Förenta Nationernas ramkonvention om klimatförändringar (Klimatkonventionen; UNFCCC) åThe rise of climate change as an issue of global concern has rested on scientific representation and understanding of the causes and impacts of, and responses to climatic change. The Intergovernmental Panel on Climate Change (IPCC), in particular, has been central to how climate change has become known as a global political problem. This thesis aims to critically examine the production, negotiatio

Mechanisms of transendothelial and tissue transport in the peritoneum. Experimental studies on rat

Popular Abstract in Swedish Njurarnas huvudsakliga funktion i kroppen är att rena blodet från slaggprodukter och reglera vätskebalansen. Hos patienter med nedsatt njurfunktion måste blodet renas på alternativa sätt. Antingen leds blodet ut via slangar till en maskin som renar blodet (hemodialys), eller används bukdialys, så kallad peritoneal dialys (PD). Vid PD häller patienten dialysvätska i bukhIn the present thesis, the quantitative role of active transport (transcytosis) in bulk transvascular protein movement in vivo was evaluated. Using chemical transcytosis inhibition (N-ethylmaleimide (NEM) and filipin), we were able to show that NEM actually increases endothelial permeability to macromolecules, probably as a result of unspecific toxic action on endothelial cells. Filipin, on the ot

Bioengineered nerve conduits and wraps for peripheral nerve repair of the upper limb

Background: Traumatic peripheral nerve injury is common and incurs significant cost to individuals and society. Healing following direct nerve repair or repair with autograft is slow and can be incomplete. Several bioengineered nerve wraps or devices have become available as an alternative to direct repair or autologous nerve graft. Nerve wraps attempt to reduce axonal escape across a direct repai

Doxapram for the prevention and treatment of apnea in preterm infants

Background: Apnea of prematurity is a common problem in preterm infants that may have significant consequences on their development. Methylxanthines (aminophylline, theophylline, and caffeine) are effective in the treatment of apnea of prematurity. Doxapram is used as a respiratory stimulant in cases refractory to the methylxanthine treatment. Objectives: To evaluate the benefits and harms of doxa

Cerebral near-infrared spectroscopy monitoring for prevention of death or neurodevelopmental disability in very preterm infants

RATIONALE: Very preterm infants (i.e. born before 32 weeks of gestation) are at risk of cerebral injury and long-term neurodevelopmental impairment. Cerebral near-infrared spectroscopy (NIRS) enables continuous monitoring of cerebral oxygenation to guide clinical management. Interest in NIRS has grown in recent years, highlighting the need for better evidence to support its clinical efficacy in im

Setting the Holocene clock using varved lake sediments in Sweden

The aim of this thesis was to study annually laminated (varved) Holocene lake sediment in Sweden, their formation and their potential as chronological and palaeoecological archives. Five lakes with continuous Holocene varved lake sediment sequences in northern (Västerbotten) and west central Sweden (Värmland) were investigated. Three of these sequences were discovered during this study, which iden

Stroke and Functional Recovery - An experimental study on environmental influence and gene expression after cortical infarcts in the rat

Popular Abstract in Swedish Närmare 30.000 svenskar drabbas årligen av stroke (slaganfall). I ungefär 85 % av fallen är orsaken en blodpropp i ett av hjärnans kärl s.k. hjärninfarkt. En avstängning av blodflödet orsakar en snabbt insättande förlust av funktionen i det drabbade området, t.ex. halvsidig förlamning, bortfall av delar av synfältet liksom störning av olika högre hjärnfunktioner såsom mAbstract Stroke is the third leading cause of death in the western world, and the number one cause of disability. 85% of all strokes are ischemic. Most stroke survivors will experience recovery of function. The mechanisms behind this improvement are partly unknown, but may involve elements of both compensation and restoration. Exposure to an enriched environment (EE) that stimulates social interac

The effect of sequence truncation and amino-acid substitutions on the biophysical properties of protein S and calbindin D9k.

Popular Abstract in Swedish Proteiner är helt nödvändiga för alla former av liv på jorden. En typisk cell består till 50-60 % av proteiner, om man bortser från vatten. Det är ett protein, hemoglobin, som transporterar syre från lungorna till kroppens celler och ger blodet dess röda färg. Det är ett protein, alfa- keratin, som bygger upp vårt hår och våra naglar. Det är två proteiner, aktin och myoProtein S is a modular protein and a cofactor in the protein C anticoagulant system. It consists of a Gla-module, a thrombin-sensitive loop, four EGF-modules and a SHBG-like module. Protein S has previously been shown to contain four binding sites with high affinities for Ca2+ (Ka>9x105 M-1 at physiological ionic strength) and at least one of the sites h

Nutritional effects of barley products — Mechanisms of action in the intestinal tract

Popular Abstract in English There is a growing prevalence of disorders associated to the metabolic syndrome globally. To reverse this trend lifestyle changes are required. Among dietary factors, dietary fibre that is associated with several health benefits plays an interesting role. Barley is highly unutilized as human food, and it contains high amounts of dietary fibre. The composition of the barBarley is one of the most important crops in the world. Although it is mainly used as the raw material for the production of beer and animal feed, it has recently attracted interest from nutritionists and consumers, due to its high content of dietary fibre, especially β-glucan, and its relation to various positive health effects. The proposed mechanisms behind the health effects are the formation

Tumor necrosis factor (TNF) inhibitors for juvenile idiopathic arthritis

Background: Juvenile idiopathic arthritis (JIA) is a rheumatic disorder that causes chronic joint inflammation beginning before the age of 16 years. Pharmacological treatment necessary to prevent joint destruction and functional impairment includes non-steroidal anti-inflammatory drugs (NSAIDs), intra-articular corticosteroids, conventional synthetic (cs) disease-modifying anti-rheumatic drugs (DM

Structural Optimization

Structural Optimization | Solid Mechanics Skip to main content This site uses cookies to enhance the user experience. By continuing to use the site you agree that cookies are used according to our Cookie Policy (on the website of LTH) . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not store any personally identi

https://www.solid.lth.se/research/structural-optimization/ - 2026-05-14

Research

Research | Packaging Logistics Skip to main content This site uses cookies to enhance the user experience. By continuing to use the site you agree that cookies are used according to our Cookie Policy (on the website of LTH) . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not store any personally identifiable info

https://www.plog.lth.se/research/ - 2026-05-14

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Report on ”Specialised course in Linear Functional Analysis”, MATP45, Fall 2020 The course has been taught in the standard way, in class, with lectures com- bined with presentations delivered by the students, until mid-November 2020, when we went over to online lectures due to the new restrictions imposed by the Lund University related to the pandemia. For these lectures via zoom I have used a whi

https://www.maths.lu.se/fileadmin/maths/Matematik_NF/Kursutvaerderingar/HT2020/MATP45HT2020KA.pdf - 2026-05-14

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Kursutvärdering Kurs: Matematisk statistik för fysiker:MASB03 Utvärderas ocks̊a p̊a LTH: Ja Lärare: Joakim Lübeck Antal studenter: 4 Svarsfrekvens: 1/4 Betyg: 0 VG, 0 G, 1 U Sammanfattning: En student svarade. För litet underlag för analys. Kommentarer: P̊a kursutvärderingen fr̊an LTH finns dock lite kritik om hur omställningen till distan- sundervisning mitt i kursen gjordes. Dettta prob

https://www.maths.lu.se/fileadmin/maths/utbildning_education/KU_Matematisk_statistik_foer_fysikerMASB03.pdf - 2026-05-14

Packaging Logistics

Packaging Logistics | Packaging Logistics Skip to main content This site uses cookies to enhance the user experience. By continuing to use the site you agree that cookies are used according to our Cookie Policy (on the website of LTH) . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not store any personally identi

https://www.plog.lth.se/ - 2026-05-14

Did the US ever ‘give back’ Greenland to Denmark, as Trump claims?

Did the US ever ‘give back’ Greenland to Denmark, as Trump claims? Did the US ever ‘give back’ Greenland to Denmark, as Trump claims? Av Rikke Lie Halberg - Publicerad den 30 januari 2026 American servicemen in Greenland, which indigenous Greenlanders call Kalaallit Nunaat, during the second world war. Signal Corps Archive / Wikimedia Commons Foto: Signal Corps Archive / Wikimedia Commons   When N

https://www.ht.lu.se/article/did-the-us-ever-give-back-greenland-to-denmark-as-trump-claims/ - 2026-05-14

WPSS_Forgotten factors in the development of dependent clauses in Swedish as a second language_defin

WPSS_Forgotten factors in the development of dependent clauses in Swedish as a second language_definitive Working Papers in Scandinavian Syntax 95 (2015), 33–43 Forgotten Factors in the Development of Dependent Clauses in Swedish as a Second Language Martje Wijers Ghent University Abstract This paper is concerned with the acquisition of Swedish dependent clauses. In a longitudinal study of Belgian

https://projekt.ht.lu.se/fileadmin/_migrated/content_uploads/wijers.subordination_01.pdf - 2026-05-14

Forskarutbildningsenkäten handledare 2020

Forskarutbildningsenkäten handledare 2020 Forskarutbildningsenkäten handledare 2020 SAMMANFATTNING John Jönsson, Avdelningen för kvalitetsstöd, LTH jo5480jo Textruta Dnr U 2021/121 1 Innehåll 2 1. Inledning Föreliggande rapport redovisar resultatet av Forskarutbildningsenkäten handledare som genomfördes vid LTH under hösten 2020. Syftet med enkäten är att följa upp handledarnas förutsättningar ino

https://www.lth.se/fileadmin/lth/anstallda/kvalitet/Resultat_i_kvalitetssystemet/Uppfoeljning_FU/Resultat_forskarutbildningen/Rapport_handledarenkaeten_LTH_2020.pdf - 2026-05-14