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Roles of Complement C1q in Pneumococcus-Host Interactions.

The fight between a human host and a bacterial pathogen is highly complicated; each party tries to outshine the other in the race for survival. In humans, the innate immune system-in particular the complement system-functions as the first line of defence against invading pathogens. During the course of evolution, however, pathogens, in order to survive and perpetuate within a host, developed multi

Coworkership and engagement : Toward a communication-centered perspective

This chapter has a twofold aim. Our first aim is to argue for a shift from viewing engagement as a psychological state to understanding it as a communication phenomenon inherently embedded in relational and interactive processes. We argue that as a communication phenomenon, engagement is best captured in the broader meaning of the verb engage, that is, “to begin and carry out an [...] activity” (M

Phase-contrast computed tomography for quantification of structural changes in lungs of asthma mouse models of different severity

Lung imaging in mouse disease models is crucial for the assessment of the severity of airway disease but remains challenging due to the small size and the high porosity of the organ. Synchrotron inline free-propagation phase-contrast computed tomography (CT) with its intrinsic high soft-tissue contrast provides the necessary sensitivity and spatial resolution to analyse the mouse lung structure in

Hydrodynamic modelling and estimation of exchange rates for Bardawil Lagoon, Egypt. An investigation of governing forces and physical processes using numerical models.

Bardawil Lagoon, a natural lagoon located on the northern coast of the Sinai Peninsula, Egypt, there are three inlets of which two are man-made connecting the lagoon with the Mediterranean Sea. The inlets are subjected to changes in morphology, due to sediment transport, over time and this may lead to degrees of closure of either inlet. The sediment transport is governed by longshore currents and

Artificial Neural Networks for Gas Turbine Modeling and Sensor Validation

The aim of this collaboration, between the division of Thermal Power Engineering and Lunds Energi AB, is to investigate the possibilities of training artificial neural networks (ANNs) with power plant operational data. For this purpose operational data from Lunds Energi's gas turbine GT10B with heat recovery unit (HRU) will be used. Furthermore a model with user interface is created to dem

Aspects on ADM1 Implementation within the BSM2 Framework

The current work of developing a control simulation benchmark goes back to the work carried out within the COST Action 682 (“Integrated Wastewater Management”) and the IAWQ Task Group on Respirometry-Based control of the Activated Sludge Process in the late 90s. The work was continued in COST Action 624 until 2003 (Copp 2002). In 2005, the IWA Task Group on Benchmarking of Control Strategies for W

Managing short-term efficiency and long-term development through industrialized construction

There is a strong need for a productive and innovative infrastructure sector because of its monetary value and importance for the development of a sustainable society. An increased level of industrialization is often proposed as a way to improve efficiency and productivity in construction projects. In prior literature on industrialized construction, there are however neither many studies addressin

Laborativa analyser av keramik från ugnarna i Hellum, Barmer och Kragelund

Laboratory analyses of the potsherds from Hellum, Barmer and Kragelund were performed in order to study the manufacturing techniques at the different sites. During the planning of the project it was suggested that the reconstructed pots to be fired in the kilns should not only have a shape resembling the original products, but also have a raw material composition as similar as possible to the medi

Potential Influence of Diet on Bomb-Pulse Dating of Human Plaque Samples

The radiocarbon concentration of different atherosclerotic plaque fragments obtained from 20 patients in Portugal, operated in 2000-2001, has been measured in order to define the year of plaque formation. A difference of 1.8-15 yr was observed, with the mean and median both 9 yr, between the bomb-pulse date estimated with the CALIBomb software and the operation date. Stable isotope (delta C-13 and

Proteomic studies of potential cerebrospinal fluid protein markers for Alzheimer's disease

By comparing the cerebrospinal fluid (CSF) proteome between Alzheimer's disease (AD) patients and controls, it may be possible to identify proteins that play a role in the disease process and thus to study the pathogenesis of AD. Two-dimensional gel electrophoresis (2-DE), SYPRO Ruby staining and mass spectrometry were used for clinical screening of disease-influenced CSF proteins in AD patients c

Hip fracture; an interruption that has consequences four months after a hip fracture. A qualitative study

Background: Effects following a hip fracture often lead to functional disabilities and increased dependence on others. Although persons sustaining a hip fracture constitute a heterogeneous group in Swedish health care, they tend to be treated as a homogenous one. Aim: The aim of this study was to reveal how previously healthy people, aged 65 years and older, described how they had adapted to daily

What is the research impact of (the ideal of) scientific truth?

This conceptual paper addresses how the emergent impact agenda is slowly but surely changing the normative framework of modern science. In order to understand such a cultural shift, we draw a chronology around the evaluation regime of research impact and identify a causal mechanism that changes the disciplinary structure of the research ecosystem. We draw upon a sociological model of scientific kn

Recrystallisation behaviour of native and processed waxy maize starch in relation to the molecular characteristics

Molecular characteristics were determined for native waxy maize starch and maize starch modified in different way (by mechanical treatment or/and acid hydrolysis). Recrystallisation behaviour was studied. Methods used in this study were MALLS, HPAEC-PAD, NMR, DSC, SEM, light microscopy. Five starch materials were subjected to storage under the same conditions in the presence of water (70 w/w%). Mo

The Nordic Housing Enabler: Inter-rater reliability in cross-Nordic occupational therapy practice

This study addresses development of a content-valid cross-Nordic version of the Housing Enabler and investigation of its inter-rater reliability when used in occupational therapy rating situations, involving occupational therapists, clients, and their home environments. The instrument was translated from the original Swedish version of the Housing Enabler, and adapted according to accessibility no

BIM Anatomy II: Standardisation Needs & Support Systems

This thesis presents the results of an investigation into BIM standardisation needs and procedural supporting mechanisms that may enable design, construction and operating (DCO) organisations to advance their deployment of Building Information Modelling (BIM) technology, and improve construction project outcomes. To achieve sustainable development requires effective information management. Buildi

Stochastic unfolding of nanoconfined DNA : Experiments, model and Bayesian analysis

Nanochannels provide a means for detailed experiments on the effect of confinement on biomacromolecules, such as DNA. Here we introduce a model for the complete unfolding of DNA from the circular to linear configuration. Two main ingredients are the entropic unfolding force and the friction coefficient for the unfolding process, and we describe the associated dynamics by a non-linear Langevin equa

EpilepsyGAN : Synthetic Epileptic Brain Activities with Privacy Preservation

Epilepsy is a chronic neurological disorder affecting more than 65 million people worldwide and manifested by recurrent unprovoked seizures. The unpredictability of seizures not only degrades the quality of life of the patients, but it can also be life-threatening. Modern systems monitoring elec-troencephalography (EEG) signals are being currently developed with the view to detect epileptic seizur

Copper Prices and Heterogeneity: The Chilean and Norwegian Cases, 1850–1913

As a first approach to the comparison between the Andean and the Nordic countries, it is their specialisation on natural resource exportation. But even though both regions exported similar commodities at the beginning of the nineteenth century, how similar were they really? In this article, we analyse thecopper exportation of Chile and Norway in order to see small differences that can have made a