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Studies on translation initiation and gene expression in Escherichia coli

In prokaryotes, several mRNA sequences surrounding the initiation codon have been found to influence the translation process; these include the downstream region and its codon context, the Shine-Dalgarno sequence and the S1 ribosomal protein-binding site. In this thesis, the purpose has been to study the role of the downstream region and Shine-Dalgarno-like sequences on early translation elongatio

Open-loop optimal control of batch chromatographic separation processes using direct collocation

This contribution presents a novel model-based methodology for open-loop optimal control of batch high-pressure liquid chromatographic (HPLC) separation processes. The framework allows for simultaneous optimization of target component recovery yield and production rate with respect to a parameterization of the input elution trajectory and fractionating interval endpoints. The proposed methodology

Retinal function and histopathology in rabbits treated with Topiramate.

Purpose To evaluate retinal function and histopathology in rabbits treated orally with the antiepileptic drug topiramate. Methods Six rabbits were treated with a daily oral dose of topiramate during a period of eight months. Six rabbits receiving water served as controls. Blood samples were analyzed for determination of topiramate serum levels in order to ensure successful drug exposition. Standar

Field variability of element concentrations in wheat and soil

Field variability of element concentrations in crops is important to consider for nutrient application as well as for evaluation of environmental hazards. The paper gives an analysis of spatially sampled wheat plant tissue in the field to determine spatial properties of 20 elements for a partly sludge-applied agricultural soil in northern Tunisia. A comparison is made with the spatial variability

Value Investing and The Magic Formula - a method for successful stock investments

With this thesis we want to prove that by using a single formula for picking stocks, Joel Greenblatt’s ‘’Magic Formula’’, it is possible to achieve returns higher than those achieved by a related index. To prove this, we will construct a portfolio, according to “The Magic Formula”, and backtest the portfolio in the Swedish stock market. The test period will be March 1999 to January 2010 and we wil

Intressekonflikter i Investmentbanker

Due to the recent financial turmoil we have noticed how exposed our financial situations are. Not only the financial market has been affected but also major socio-economic crises have risen as a result of the recession. Despite this, there is a willingness to take part in trading on the financial market. Considerable amount of money is involved in the securities market which makes it obvious that Due to the recent financial turmoil we have noticed how exposed our financial situations are. Not only the financial market has been affected but also major socio-economic crises have risen as a result of the recession. Despite this, there is a willingness to take part in trading on the financial market. Considerable amount of money is involved in the securities market which makes it obvious that

The effects of parking accessibility on work commuting - Considering parking policies as a mobility management tool for Lund

Abstract This thesis addresses the effects of parking accessibility on work commuting and the potential to use parking policies as a tool to support mobility management and enhance sustainable commuting in Lund. The structure rests on two folds: first, it provides a theoretical background on different parking policies and factors influencing work commuting; second, it provides an analysis of Lund

Labour regime changes and workers’ social protection : A study of the 3Ts small-scale mining sector formalisation process in Rwanda

I denna studie undersöks en vanlig fråga i utvecklingsländer - att informella arbetsrelationer kvarstår när den småskaliga gruvsektorn (ASM) ställs under statlig kontroll. Detta undersöks genom en studie av formaliseringsreformer i Rwandas 3Ts-sektor (tenn, tantal, volfram) för småskalig gruvdrift, som intensifierades från 2010. Forskningen syftar till att förklara den roll som arbetskraft, som båThis study explores a common issue in developing countries – the persistence of informal labour relations when the artisanal and small-scale mining (ASM) sector is brought under state control. It investigates this through a study of formalisation reforms in Rwanda’s 3Ts (tin, tantalum, tungsten) small-scale mining sector, which intensified from 2010. The research aims to explain the role that labo

The Influence of Different Ultrafiltration Set-ups on Mineral Partitioning Between Skim Milk Streams

Ultrafiltration (UF), a widely utilised membrane-based process used in the dairy industry, is crucial for standardising milk constituents, especially proteins. However, depending on the filtration set-up, the extent of the physicochemical properties of the concentrate can be modulated. This study compares the impacts of two UF configurations, cross-flow (CF-UF) and dead-end (DE-UF), on the mineral

Investigation of Some Heat Transfer Surfaces for Gas Turbine Recuperators

A part of this thesis has been devoted to present general recuperator technology such as available gas turbine recuperator types, applications where recuperators are utilized, recuperator materials etc. An investigation of some compact and highly efficient heat transfer surfaces, for intended use in gas turbine recuperators, include the following surfaces: · Cross Wavy (CW) primary surface. · Cor

A platform for Packaging Logistics Development: a systems approach

Packaging Logistics is a concept that recognises the need for coordination of the packaging system and its manifold functions throughout a package’s life cycle. Packaging Logistics is an area in need for substantial theoretical building. This dissertation elaborates on its underpinnings and suggests conceptual models that should be useful in better understanding the core of the concept, its undere

An overview of the spectral induced polarization method for near-surface applications

Over the last 15 years significant advancements in induced polarization (IP) research have taken place, particularly with respect to spectral IP (SIP), concerning the understanding of the mechanisms of the IP phenomenon, the conduction of accurate and broadband laboratory measurements, the modelling and inversion of IF data for imaging purposes and the increasing application of the method in near-

Inverse modeling of European CH4 emissions 2001-2006

European CH4 emissions are estimated for the period 2001-2006 using a four-dimensional variational (4DVAR) inverse modeling system, based on the atmospheric zoom model TM5. Continuous observations are used from various European monitoring stations, complemented by European and global flask samples from the NOAA/ESRL network. The available observations mainly provide information on the emissions fr

Ultrafiltration and nanofiltration of E-stage bleaching plant effluents of a sulphite pulp mill

This work addresses the assessment of ultrafiltration (UF) and nanofiltration (NF) for the treatment of a bleaching plant effluent (BPE) from aPortuguese sulphite pulp mill (Caima-Indústria de Celulose,S.A.) with the two-fold objective of water consumption minimization and by-products valorization. This is to be achieved through the recycling of UF/NF permeates as process water and the concentrati

The Gaia -ESO survey : 3D NLTE abundances in the open cluster NGC 2420 suggest atomic diffusion and turbulent mixing are at the origin of chemical abundance variations

Atomic diusion and mixing processes in stellar interiors influence the structure and the surface composition of stars. Some of these processes cannot yet be modelled from the first principles, and they require calibrations. This limits their applicability in stellar models used for studies of stellar populations and Galactic evolution. Aims. Our main goal is to put constraints on the stellar struc

Software Quality Assurance - Concepts and Misconceptions

Software quality engineering is concerned with building software products with required quality and assessing the level of quality. Software processes are important assets in achieving and assessing the software quality. Furthermore the adherence to defined processes is a key issue to having the software engineering under control and to enable process improvement. The software quality assurance (S

Genetic testing and surveillance guidelines in hereditary pheochromocytoma and paraganglioma

Pheochromocytoma and paraganglioma (PPGL) are rare tumours and at least 30% are part of hereditary syndromes. Approximately 20% of hereditary PPGL are caused by pathogenic germ line variants in genes of the succinate dehydrogenase complex (SDHx), TMEM127 or MAX. Herein we present guidelines regarding genetic testing of family members and their surveillance based on a thorough literature review. Al