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Exploring Themes and Challenges in Developing Sustainable Supply Chains - A Complexity Theory Perspective

To develop sustainable supply chains in a way that their negative environmental and social effects are minimized, shortand long-term targets should be set. The transformation of supply chains towards these targets calls for the development of innovative strategies and the need to continuously identify, classify, and tackle the challenges that can hinder the execution of such strategies. To develop

The proteoglycan mimecan is associated with carotid plaque vulnerability and increased risk of future cardiovascular death

Background and aims: A vulnerable plaque is an atherosclerotic plaque that is rupture-prone with a higher risk to cause cardiovascular symptoms such as myocardial infarction or stroke. Mimecan or osteoglycin is a small leucine-rich proteoglycan, important for collagen fibrillogenesis, that has been implicated in atherosclerotic disease, yet the role of mimecan in human atherosclerotic disease rema

Methylation patterns and chromatin accessibility in neuroendocrine lung cancer

Lung cancer is the worldwide leading cause of death from cancer. Epigenetic modifications such as methylation and changes in chromatin accessibility are major gene regulatory mechanisms involved in tumorigenesis and cellular lineage commitment. We aimed to characterize these processes in the context of neuroendocrine (NE) lung cancer. Illumina 450K DNA methylation data were collected for 1407 lung

Hepatic Leukemia Factor Maintains Quiescence of Hematopoietic Stem Cells and Protects the Stem Cell Pool during Regeneration

The transcription factor hepatic leukemia factor (HLF) is strongly expressed in hematopoietic stem cells (HSCs) and is thought to influence both HSC self-renewal and leukemogenesis. However, the physiological role of HLF in hematopoiesis and HSC function is unclear. Here, we report that mice lacking Hlf are viable with essentially normal hematopoietic parameters, including an intact HSC pool durin

Food sources of fat and sex hormone receptor status of invasive breast tumors in women of the malmö diet and cancer cohort.

We examined associations between food intakes and incident breast cancer, defined by estrogen receptor (ER) and progesterone receptor (PR) status in the Malmö Diet and Cancer cohort (17,000 women aged 45-73 yr). The hazard ratios (HRs) of ER+PR+ (n = 270), ER+PR- (n = 87), and ER-PR- (n = 61) tumors and all cancer (n = 544) were estimated after 10 yr of follow-up. In multivariate analysis of ER+PR

Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia.

Acute myeloid leukemia (AML) is associated with a poor survival rate, and there is an urgent need for novel and more efficient therapies, ideally targeting AML stem cells that are essential for maintaining the disease. The interleukin 1 receptor accessory protein (IL1RAP; IL1R3) is expressed on candidate leukemic stem cells in the majority of AML patients, but not on normal hematopoietic stem cell

Madeline gunn - catch 22 a study on choice editing

Catch-22? The Potential For Retailers To Practice ‘Choice Editing’ As A Policy Tool For Sustainable Consumption Author: Madeline Gunn Lund University Masters in Environmental Studies and Sustainability Science (LUMES) maddy.gunn@gmail.com Supervisor: Professor Oksana Mont Institute of International Industrial and Environmental Economics (IIIEE) oksana.mont@iiiee.lu.se A Thesis Submitted to Lunds U

https://www.lumes.lu.se/sites/lumes.lu.se/files/madeline_gunn_-_catch_22_a_study_on_choice_editing.pdf - 2026-05-20

Slutrapport peer-support vgr

Egen erfarenhet som unikt arbetsverktyg Slutrapport 2018-02-16 Författare: Jakob Wenzer Egen erfarenhet som unikt arbetsverktyg Utvärdering av projektet PEER Support inom psykiatrin i Västra Götalandsregionen Egen erfarenhet som unikt arbetsverktyg Utvärdering av projektet PEER Support inom psykiatrin i Västra Götalandsregionen 1 Innehåll Introduktion ..............................................

https://www.cepi.lu.se/sites/cepi.lu.se/files/slutrapport_peer-support_vgr.pdf - 2026-05-20

Enhancing individual glomerular filtration rate assessment : can we trust the equation? Development and validation of machine learning models to assess the trustworthiness of estimated GFR compared to measured GFR

Background: Creatinine-based estimated glomerular filtration rate (eGFR) equations are widely used in clinical practice but exhibit inherent limitations. On the other side, measuring GFR is time consuming and not available in routine clinical practice. We developed and validated machine learning models to assess the trustworthiness (i.e. the ability of equations to estimate measured GFR (mGFR) wit

Trajectory-Ordered Objectives for Self-Supervised Representation Learning of Temporal Healthcare Data Using Transformers : Model Development and Evaluation Study

Background: The growing availability of electronic health records (EHRs) presents an opportunity to enhance patient care by uncovering hidden health risks and improving informed decisions through advanced deep learning methods. However, modeling EHR sequential data, that is, patient trajectories, is challenging due to the evolving relationships between diagnoses and treatments over time. Significa

Kommunikation Medfak 250828

PowerPoint Presentation Communication at the Faculty of Medicine COMMUNICATIONS SECTION, FACULTY OF MEDICINE 2025 WHAT IS COMMUNICATION? Communicare = to make together Presenter Notes Presentation Notes The word communication comes from the latin Communicare, which means to make together. Communication is fundamental for relationships, cooperation, achieving common goals, and for building and main

https://www.intramed.lu.se/en/sites/intramed.lu.se.en/files/2025-08/Kommunikation_Medfak_250828.pdf - 2026-05-20

Non-core business talent attraction

Research Question and Purpose: The research question will investigate what talent attraction looks like in non-core businesses sharing the name of the core business. The purpose of this thesis is to explore talent attraction in the context of non-core businesses sharing the name of the core business. Methodology: The research paradigm is a relativist ontology with a social constructivist epistemol

Vår barnaskara - Ett arbete om social adekvans och barns rättigheter

Violence against children occurs worldwide despite explicit prohibitions. In Article 19 in the United Nations Convention on the Rights of the Child there is a prohibition against physical and psychological violence towards children. States shall take all appropriate legislative, administrative, social and educational measures to protect the child. According to Article 23 (4) the convention state

Terpenoid Plant Metabolites - Structural Characterization and Biological Importance

In response to the challenges of their local environments, organisms produce of a large number of chemical diverse compounds with complex stereochemistry and reactive functional groups. These characteristics enable them to interact and bind specifically to biological target molecules and exert various biological activities, and have assured that Natural products continues to be an important source

Participatory action research in hyperlocal media studies: reflection on methodology

The use of participatory action research in media studies is under development and has the last years become notable as a new way of exploring changes that has taken place on the media market the last decades. Media corporations in Sweden continue shutting down local editorial offices and centralize local news reporting to the head editorials. An absence of local reporting in several rural areas iThe use of participatory action research in media studies is under development and has the last years become notable as a new way of exploring changes that has taken place on the media market the last decades. Media corporations in Sweden continue shutting down local editorial offices and centralize local news reporting to the head editorials. An absence of local reporting in several rural areas i

Plasma S1P (Sphingosine-1-Phosphate) Links to Hypertension and Biomarkers of Inflammation and Cardiovascular Disease : Findings From a Translational Investigation

S1P (Sphingosine-1-phosphate) is an important regulator of immune cell trafficking and vascular dysfunction contributing to the development and progression of overt hypertension. Although targeting S1P signaling revealed therapeutic potential in different experimental hypertension studies, validations of S1P-blood pressure (BP) associations in humans are lacking. In a translational approach, we ex

Reply to letter by Deng et al. "Could the levels of inflammation biomarkers predict OA? : Comment on the article by Roemer FW et al."

As explained in the methods-section, we chose to analyze the 2-year data in regard to inflammatory activity based on MRI and synovial biomarkers (and not earlier time points) as our aim was to capture patients that experienced "prolonged" or chronic inflammation, which may be regarded as a potential risk factor for osteoarthritis (OA) development. Virtually all patients of an acute injury cohort (