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Objective: Follicle-stimulating hormone (FSH) receptor expression has been reported in many extra-gonadal tissues, raising the question of non-reproductive effects of FSH. Because of increasing usage of FSH in treatment of male infertility, deeper knowledge of possible harmful off-target effects of FSH is warranted. Methods: In total, 33 healthy young men (mean age 30 years) were included in the s
Background: Colorectal cancer presents as emergencies in 20% of the cases. Emergency resection is associated with high postoperative morbidity and mortality. The specialization of the operating team in the emergency settings differs from the elective setting, which may have an impact on outcome. The aim of this study was to evaluate short- and long-term outcomes following emergent colon cancer sur
Background: The 2019 European Working Group on Sarcopenia in Older People (EWGSOP2) and the Sarcopenia Definitions and Outcomes Consortium (SDOC) have recently proposed sarcopenia definitions. However, comparisons of the performance of these approaches in terms of thresholds employed, concordance in individuals and prediction of important health-related outcomes such as death are limited. We addre
BACKGROUND: Prolonged opioid use (more than 90 days) after injury puts the patient at risk for adverse effects. We investigated the patterns of opioid prescription after distal radius fracture and the effect of pre- and post-fracture factors on the risk for prolonged use.METHODS: This register-based cohort study uses routinely collected health care data, including purchases of prescription opioids
Aim: To perform a model-based analysis of the short- and long-term health benefits and costs of further increased implementation of empagliflozin for people with type 2 diabetes and established cardiovascular disease (eCVD) in Sweden. Materials and Methods: The validated Institute for Health Economics Diabetes Cohort Model (IHE-DCM) was used to estimate health benefits and a 3-year budget impact,
Clinical pain is often linked to poor body mechanics, with individuals sometimes presenting multiple painful disorders. Such disorders may be influenced by behaviors that affect the general resiliency and health of the musculoskeletal system. We aimed to develop a self-reported scale using the Malmö Diet and Cancer Study questions on work-related body mechanical exposures. An expert panel identifi
Field-resolved two-dimensional spectroscopy reveals the sub-cycle gain dynamics of a free-running terahertz quantum cascade laser and disentangles resonantly enhanced nonlinearities up to eight-wave mixing in a regime where gain replaces absorption.
Infrared drying characteristics and quality variations (color change, hardness, contents of polyphenol and flavonoid) of lily bulbs under blanching pretreatment are investigated. Influences of parameters such as pretreatment temperature and time and infrared drying temperature are discussed. Effective moisture diffusivity coefficient, activation energy, and energy consumption were calculated. Resu
OBJECTIVE: Most earlier studies on occupational risk of COVID-19 covering the entire workforce are based on relatively rare outcomes such as hospital admission and mortality. This study examines the incidence of SARS-CoV-2 infection by occupational group based on real-time PCR (RT-PCR) tests.METHODS: The cohort includes 2.4 million Danish employees, 20-69 years of age. All data were retrieved from
Future generations of computing systems need to continue increasing processing speed and energy efficiency in order to meet the growing workload requirements under stringent environmental constraints. As a result, domain-specific hardware accelerators and platforms have become widely used. In addition to the conventional approach, where memory and processing elements are separated, an emerging app
Emerging evidence suggests differential effects of therapeutic antibiotics on infant T cell responses to pathogens. In this study, we explored the impact of the treatment of mouse infants with amoxicillin and the human milk-derived antimicrobial HAMLET (human alpha-lactalbumin made lethal to tumor cells) on T cell responses to Streptococcus pneumoniae. Lung cells and splenocytes were isolated fro
For the supercritical n-decane horizontally flowing in a rectangular channel of an active regenerative cooling system, a transient thermal-fluid-structure coupling method is employed to investigate the unsteady thermal-hydraulic characteristics and the wall deformation at a starting stage. The temperature distributions of the fluid domain and solid domain along the flow direction are investigated
We investigate a Bose-Bose mixture across the miscible-immiscible phase transition governed by quantum fluctuations in one dimension. We find the recently predicted so-called mixed bubbles as ground states close to the mean-field miscible-immiscible threshold. These bubbles form a pocket of miscibility, separated by one of the components. The collective excitations reflect the symmetry breaking re
Background: Patient representatives are increasingly engaged in quality in health care, and even though quality data are publicly available, correct interpretation may be challenging. We designed a randomized study with the primary aim to examine the association between preferred data presentation format and the interpretation of quality data among cancer patients and relatives. Material and metho
