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Purpose: Elevated copeptin, a vasopressin marker, is linked to metabolic disease, and obese rats with low-vasopressin concentration had a decreased risk of liver steatosis. We here investigated the association between copeptin and nonalcoholic fatty liver disease (NAFLD) and possible differences in copeptin concentration between ethnicities. Methods: In this cross-sectional study of 361 South Afri

Aims: Adaptation to low oxygen of hematopoietic stem cells (HSCs) in the bone marrow has been demonstrated to depend on the activation of hypoxia-inducible factor (HIF)-1α as well as the limited production of reactive oxygen species (ROS). In this study, we aimed at determining whether HIF-1α is involved in protecting HSCs from ROS. Results: Oxidative stress was induced by DL-buthionine-(S,R)-sulf

BACKGROUND AND OBJECTIVE: Although the effects of 5-α-reductase inhibitors (5-ARIs) on prostate-specific antigen (PSA) have been well-studied, the effects on other kallikrein markers have not been firmly established. Accordingly, a statistical model based on blood measurements of four kallikreins-known commercially as the "4Kscore"-cannot be used for men taking 5-ARIs. We investigated how finaster

I ett samhälle med ökad globalisering blir regler angående den internationella privat- och processrätten allt viktigare. Denna uppsats behandlar lagvalsregler, vilka går att finna i Romkonventionen. Romkonventionens huvudregel är lagvalsfrihet. Det finns dock bestämmelser i konventionen som inskränker denna möjlighet. Artikel 7 rörande internationellt tvingande regler är ett exempel på detta och ä

This report contains a description of the fire safety situation of Holmagården, which is a residence for elderly with special needs, in Svedala, Sweden. The purpose is to evaluate the personal safety in case of fire where concern has taken to the health status of the individuals at Holmagården. Three different fire scenarios have been the starting direction for modelling and calculating. To estima

Vid en diskussion om nivån på den svenska bolagsskatten är det av stor vikt att avgöra huruvida diskussionen rör den nominella eller den effektiva skattesatsen. Den nominella skattesatsen uppgår till 28 procent och återfinns i 65 kap. 14 § IL. Den effektiva skattesatsen är däremot inte given utan kan i viss utsträckning påverkas, eftersom den bestäms genom att dividera skatt på årets resultat med

The European Border and Coast Guard was launched on October 6th, 2016. It was established through Regulation 2016/1624 and replaces the European Agency for the Management of Operational Cooperation at the External Borders of the Member States. The Agency is more known as Frontex. The objective with this thesis is to examine two problems in Regulation 2016/1624 that was addressed at the negotiatio

Methodology: The method used is a single case study in a high tech company in Sweden, leader in network camera market. This work is a qualitative research, in which an inductive method and deductive analysis has been applied. Grounded-theory techniques have been used; eight semi-structured interviews were conducted-carefully and objectively selected following purposive sampling. Theoretical persp

Anaerobic digestion (AD) of wastes and residues is a widely applied and explored process. However, when the process is not optimized, inadequate concentrations of nutrients and inhibitory compounds are common and can lead to low maximum organic loading rates and increased risk of process problems, low organic dry solids degradation rate and reduced methane yields. To overcome process instability a

Air pollution is a serious problem today, both from an environmental and from a health point of view. Especially in cities, particles smaller than 10 µm in aerodynamic diameter (PM10) can reach high concentrations. These particles are dangerous, even at low concentrations, since they are small enough to enter the lungs. In order to estimate the concentration of air pollutants, different measureme

Salinisation is a global issue which leads to desertification and soil degradation and exposure to salt is also known to inhibit microbial activity and plant growth. This study was conducted to determine the influence of salinity on microbial activity of a non- saline soil. By using Salt Induced Community Tolerance (SICT) concept I found that microbial community tolerance to salt can be induced in

The European spruce bark beetle is considered as one of the most destructive forest insects to Norway spruce trees in Europe. Climate change may increase the frequency and intensity of bark beetle outbreaks. It is therefore of vital importance to detect the bark beetle outbreaks and take it under control to prevent further damages. Remote sensing techniques may provide a cost-efficient solution to

The enunciation of the principle of equality and non-discrimination is of fundamental source in international human rights laws and EU-law and has a prominent place in the Icelandic constitution. The principles of equality and non-discrimination are based on various legal concepts that have evolved mainly in international and regional human rights or equality jurisprudence. International legal pro