Sökresultat

Due to their high reactivity, organolithium and organomagnesium addition to ketones is usually performed under inert atmosphere at low temperature. Recent work has shown that, by dissolving the substrate in deep eutectic solvents (DES), these processes can be carried out on the benchtop, in air at room temperature. Surprisingly, the organometallic reagent, added to the DES from an organic solu

InP quantum dots have emerged as a promising ecofriendly alternative to cadmium-based QDs for next-generation display applications. However, red-emitting InP QDs synthesized via aminophosphine precursors still suffer from broad emission spectra and limited stability. In this study, we present a strain-engineered InP/ZnSe/ZnSexS1-x/ZnS QD structure featuring a gradient alloyed ZnSexS1-x shell that

Introduction: Human papillomavirus (HPV) infection is associated with tonsillar and base-of-tongue squamous cell carcinomas (TSCC/BOTSCC). We evaluated the relative risk (RR) of TSCC/BOTSCC in the husbands of women with anogenital cancer using the Swedish family database. Methods: The Swedish family database includes 3.5 million families and 16 million individuals identified since 1932 and linked

Objective: A diagnosis of childhood cancer is profoundly devastating for families, with well-recognized effects on parental mental health. However, its impact on parental somatic health remains poorly understood, particularly regarding potential long-term cumulative burden. These persistent somatic diseases require frequent clinic visits for ongoing management and adversely affect parents' quality

Background: The increased risk of colorectal cancer (CRC) associated with family history of both colorectal in situ or invasive carcinomas (Stage 0 to IV) and colorectal polyps is attributed solely to family history of CRC, resulting in an underestimation of the actual risk. We aimed to assess the association between overall and early-onset CRC (EOCRC) risk and family history of both colorectal ca

As the total cost of renewable electricity falls lower than the price of fossil fuel, not only can electricity be used to replace fossil fuels using batteries in vehicles but it can also be used to produce fuels. This makes it possible to replace fuels in sectors not easily directly electrified. It also provides new ways of balancing the electricity system. When renewable electricity is cheap a lo

INTRODUCTION: While the characteristics and medical management of patients treated with long-term oxygen therapy (LTOT) have transformed during the last decades, the evidence base for LTOT itself remains largely unchanged. This study aimed to compare the risk of hospitalization and death among hypoxemic patients discontinuing LTOT, with that of controls continuing therapy.METHODS: This was a retro

Polyoxometalates (POMs) and their instrinsic discrete nature has enabled them to support a wide range of research spanning solution-speciation chemistry, biological/medical assays, catalytic processes and fundamental crystallography. The structure-property relationship of POMs are a consequence of their constiuent metal atoms, which inevitably are formed under specific regimes - for simplicity, ac

Background and objective: Prostate cancer (PC) is the second most common cancer and a leading cause of death among males. In this systematic review we evaluated cohort studies and randomized controlled trials (RCTs) on the relationship between dietary patterns and PC risk, progression, mortality, and biomarkers. Methods: A systematic search of MEDLINE, Embase, and Cochrane Central was conducted th

Introduction: Two large multicentre European hospital networks have estimated vaccine effectiveness (VE) against COVID-19 since 2021. Aim: We aimed to measure VE against PCR-confirmed SARS-CoV-2 in hospitalised severe acute respiratory illness (SARI) patients≥20 years, combining data from these networks during Alpha (March–June)- and Delta (June–December)dominant periods, 2021. Methods: Forty-six

Objectives: The objective was to explore if adverse events during radical prostatectomy for prostate cancer were associated with oncological outcomes. A further objective was to identify risk factors for adverse events. Methods: A post-hoc study nested in a prospective, controlled trial of radical prostatectomy by robot assisted laparoscopic or open retropubic approach in Sweden. Adverse events du

Rationally designing and fabricating high-performance core–shell nanostructures for catalytic organic synthesis is significant yet challenging. Here, we report a solvothermal/calcination strategy to prepare novel core–shell iron–aluminum oxide (FeAlOx) nanosphere-based nanoreactors incorporating active heterometals (AHM = Pd, Cu, or Mn). Leveraging the synergistic benefits of their unique core–she

Global health is a multidisciplinary field focused on improving health and achieving equity in health for all people worldwide. The COVID-19 pandemic left a profound and lasting impact on global mental health, triggering a surge in anxiety, depression, and stress-related disorders across all age groups and regions. As the world transitions into the post-COVID period, mental health has emerged as a

BACKGROUND AND OBJECTIVE: Prostate cancer (PC) and dementia may commonly co-occur; yet, prior evidence for bidirectional associations is inconsistent. This study aims to determine the associations between PC and dementia in large population-based studies, which may further inform clinical care. METHODS: To assess the dementia risk in men with PC, a national cohort study was conducted in 178 746 me

Tick-borne encephalitis virus (TBEV) causes tick-borne encephalitis (TBE), a severe and sometimes life-threatening disease characterized by viral invasion of the central nervous system with symptoms of neuroinflammation1,2. As with other orthoflaviviruses—enveloped, arthropod-borne RNA viruses—host factors required for TBEV entry remain poorly defined. Here we used a genome-scale CRISPR–Cas9-based

Nanoreactors have attracted extensive research and attention in the field of catalysis due to their unique surface/interface structures and physicochemical properties. However, conventional nanoreactors have limited catalytic performance due to the confinement of their active components in the “nanochamber”. Herein, low-content active metal (AM, AM = Pd, Cu) decorated yolk-shelled FeCoNiOx (AM/FeC

Let v1 and v2 be two distinct vertices of an equilateral tree T0. Let ϕN(i) (i=1,2) be the characteristic functions of the Sturm-Liouville problem on T0 rooted at vi with Neumann conditions at the root and let ϕD(i) (i=1,2) be the characteristic functions of the Sturm-Liouville problem on T0 with Dirichlet conditions at the root. We prove that if attaching any tree to T0 at the vertices v1 and v2

Background: The optimal timing of oral anticoagulation for prevention of early ischaemic stroke recurrence in people with acute ischaemic stroke and atrial fibrillation remains uncertain. We aimed to estimate the effects of starting a direct oral anticoagulant (DOAC) early (≤4 days) versus later (≥5 days) after onset of ischaemic stroke. Methods: For this systematic review and meta-analysis we sea