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Background: Low socioeconomic position (SEP) in adulthood has been associated with overweight and obesity in high-income countries. However, little is known about the contribution of childhood SEP to weight change. Using a Swedish general population sample, this study aimed to examine the association between five-year weight gain among adults and socioeconomic position in childhood and adulthood.

We demonstrate that the detected emission intensity from YOYO-labeled DNA molecules confined in 180 nm deep Si/SiO2 nano-funnels changes significantly and not monotonically with the width of the funnel. This effect may be of importance for quantitative fluorescence microscopy and for experiments with a tight photon budget.

The observed increased risks of gastric cancer among first-generation immigrants compared to those in Swedes suggest the role of childhood environmental exposure in the risk of this disease.

Objective The Systemic Lupus International Collaborating Clinics (SLICC) group revised and validated the American College of Rheumatology (ACR) systemic lupus erythematosus (SLE) classification criteria in order to improve clinical relevance, meet stringent methodology requirements, and incorporate new knowledge regarding the immunology of SLE. Methods The classification criteria were derived from

PURPOSE: Previous studies of neighborhood deprivation and mental disorders have yielded mixed results, possibly because they were based on different substrata of the population. We conducted a national multilevel study to determine whether neighborhood deprivation is independently associated with psychiatric medication prescription in a national population. METHODS: Nationwide outpatient and inpat

Inflammatory responses play a vital role at different stages of colorectal carcinogenesis. C-type lectins mediate inflammatory/immune responses and participate in immune escape of pathogens and tumors. Our study aimed to evaluate the correlation between polymorphisms in three C-type lectin genes, CD209, MBL2 and REG4, and colorectal cancer (CRC) risk and clinical outcome. We genotyped 15 potential

Etching is an essential tool for the creation of nanostructures, where patterned metal structures can be used as masks. Here, we investigate HCl gas etching of InP substrates decorated with Au nanoparticles, and find that the etch rate is strongly increased at the Au-InP interfaces. The {111}A facets of the InP are preferentially etched. The metal nanoparticles follow in the etch direction, thereb

The receptor tyrosine kinase inhibitor cabozantinib (XL184, BMS-907351 Cometriq) has displayed impressive clinical activity against several indications, culminating in its recent approval for medullary thyroid cancer. Among malignancies with tropism for the bone (prostate, breast), one striking feature of early clinical reports about this drug has been the rapid and complete resolution of bone sca

Hydroxylated polybrominated diphenyl ethers (OH-PDBEs) are exogenous, bioactive compounds that originate, to a large extent, from anthropogenic activities, although they are also naturally produced in the environment. In the present study nine new authentic OH-PBDE reference standards and their corresponding methyl ether derivatives (MeO-PBDEs) were synthesised and characterised by NMR spectroscop

Snus is a smokeless tobacco product, widely used among Swedish men and increasingly so elsewhere. There is debate as to whether snus is an acceptable "harm-reduction" tobacco product. Since snus use delivers a dose of nicotine equivalent to cigarettes, and has been implicated in cardiac arrhythmia because of associations with sudden cardiovascular death, a relation with atrial fibrillation is plau

Single-nucleotide polymorphisms in Toll-like receptor 5 (TLR5), encoding a sensor for flagellin, have been shown to influence cytokine responses to intestinal bacteria and to be associated with significant alterations in the survival of colorectal carcinoma (CRC) patients. These findings point to a link between TLRs and CRC that may have both therapeutic and prognostic/predictive implications.

Correlated micro-photoluminescence (μPL) and cathodoluminescence (CL) measurements are reported for single core-shell InP-InAs wurtzite nanowires grown using metal-organic vapor phase epitaxy. Samples covering a radial InAs shell thickness of 1-12 ML were investigated. The effective masses for the wurtzite material were determined from the transition energy dependence of the InAs shell thickness,

Introduction: We have previously shown that a tag single nucleotide polymorphism (rs10235235), which maps to the CYP3A locus (7q22.1), was associated with a reduction in premenopausal urinary estrone glucuronide levels and a modest reduction in risk of breast cancer in women age <= 50 years. Methods: We further investigated the association of rs10235235 with breast cancer risk in a large case cont

Cardiac rehabilitation (CR) is a well established intervention for secondary prevention after myocardial infarction (MI), yet substantial variability in CR delivery and patient outcomes persists globally. This review provides an in-depth overview of the SWEDEHEART-CR registry, a comprehensive Swedish national quality registry that has facilitated continuous quality improvement and clinical researc

Background: This study investigated the moderating role of household disposable income and family type on the association between precarious employment (PE) and diagnosed mental disorders. Methods: This longitudinal study used register data from the Swedish Work, Illness, and Labour-market Participation (SWIP) cohort. The study population included all individuals aged 27–65 who were employed in 20

BACKGROUND: Pesticides play a crucial role in pest control; however, exposure remains high, particularly among smallholder farmers in low-income and middle-income countries (LMICs) with little access to pesticide safety training. This study aimed to provide comparative biomarker-based evidence from Latin America and Africa and identify actionable determinants of exposure to inform context-specific

PURPOSE OF REVIEW: To summarize and critically interpret new evidence (from the last 12-18 months) on the associations between obesity and breathlessness, including epidemiology, physiological mechanisms, diagnostic challenges, and treatment approaches.RECENT FINDINGS: Multiple large cohorts confirm that obesity is one of the strongest independent predictors of exertional breathlessness. Recent wo

Despite recommendations to use oral lipid-lowering therapies (LLT) in secondary prevention of atherosclerotic cardiovascular disease, numerous studies have shown substantial under-utilization. We assessed long-term persistence and dynamics of adherence to oral LLTs in patients after their first ever myocardial infarction (MI) in Sweden. A total of 83,407 patients with a MI (2010–2017) and who were