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Palaeomagnetic data are used to study the configurations of continents during the Proterozoic. Applying stringent reliability criteria, the positions of the continents at 12 times in the 2.45- to 1.00-Ga period have been constructed. The continents lie predominantly in low to intermediate latitudes. The sedimentological indicators of palaeoclimate are generally consistent with the palaeomagnetic l
Background and Purpose-The proportion of immigrants has increased in Sweden markedly during the last decades, as in many other Western countries. Incidence of stroke has increased during this period. However, it is primarily unknown whether incidence of stroke and stroke subtypes in Sweden is related to country of birth. Methods-Incidence of first-ever stroke was followed during 10 years in a coho
As a global society we are entering an era where land areas and land-based resources are coming to the fore once again for capital accumulation and economic growth, for the first time since the end of the 18th century when Malthus forecasted a contradiction between population growth and agricultural output. That constraint on economic growth, imposed by limited land areas, was overcome by the comb
Lipolysis is an important metabolic pathway controlling energy homeostasis through degradation of triglycerides stored in lipid droplets and release of fatty acids. Lipid droplets of mammalian cells are coated with one or more members of the PAT protein family, which serve important functions in regulating lipolysis. In this study, we investigate the mechanisms by which PAT family members, perilip
Heparan sulfate 3-O-sulfotransferase transfers sulfate to the 3-OH position of a glucosamine residue of heparan sulfate (HS) to form 3-O-sulfated HS. The 3-O-sulfated glucosamine residue contributes to two important biological functions of HS: binding to antithrombin and thereby carrying anticoagulant activity, and binding to herpes simplex viral envelope glycoprotein D to serve as an entry recept
The nexus of population growth and changing diets has increased the demands placed on agriculture to supply food for human consumption, animal feed and fuel. Rising incomes lead to dietary changes, from staple crops, towards commodities with greater land requirements, e.g. meat and dairy products. Despite yield improvements partially offsetting increases in demand, agricultural land has still been
Carbon pricing, including carbon taxes and emissions trading, has been adopted by different kinds of polities worldwide. Yet, beyond the increasing adoption over time, little is known about what polities–countries as well as sub- and supranational entities–adopt carbon pricing and why. This paper explores patterns of adoption (both implemented policies and those scheduled to be) through cluster an
OBJECTIVE: To identify ways that provision of hemophilia care can be maximized at the local level, irrespective of available resources or cultural or geographic challenges.METHODS: The SHIELD group used its multinational experience to share examples of local initiatives that have been employed to deliver optimal hemophilia care.RESULTS: The examples were reviewed and categorized into four key them
Although climate change and international trade are interdependent, policy-makers often address the two topics separately. This may inhibit progress at the intersection of climate change and trade and could present a serious constraint for global climate action. One key risk is carbon leakage through emission outsourcing, i.e. reductions in emissions in countries with rigorous climate policies bei
Polycentrism has gradually become a newly emergent dimension of global urbanization. Many countries worldwide have tailored plans suited to functional polycentricity, in light of the prevalent “ghost cities” or “empty towns” as lessons from the morphologically polycentric development practices. However, the subject of defining and measuring functional polycentricity is still in an initial developm
BACKGROUND: Dysbiosis of the oral mycobiome has been linked to some diseases, including cancers. However, the role of oral fungal communities in nasopharyngeal carcinoma (NPC) carcinogenesis has not previously been investigated.METHODS: We characterized the oral salivary fungal mycobiome in 476 untreated incident NPC patients and 537 population-based controls using fungal internal transcribed spac
In recent years, the flash flood occurs frequently and intensively. It has become a world-wide focus in the field of disaster prevention and mitigation. The flash flood critical rainfall determination method, flash floods forecasting model and experience forecasting method are the most commonly used methods. This study focused on the application of hydrological models for flash floods simulation.T
Things such as organizations, persons, or locations are ubiquitous in all texts circulating on the internet, particularly in the news, forum posts, and social media. Today, there is more written material than any single person can read through during a typical lifespan. Automatic systems can help us amplify our abilities to find relevant information, where, ideally, a system would learn knowledge
Climate change mitigation requires rapid expansion of low-carbon electricity but there is a disagreement on whether available technologies such as renewables and nuclear power can be scaled up sufficiently fast. Here we analyze the diffusion of nuclear (from the 1960s), as well as wind and solar (from the 1980-90s) power. We show that all these technologies have been adopted in most large economie
Ending the use of unabated coal power is a key climate change mitigation measure. However, we do not know how fast it is feasible to phase-out coal on the global scale. Historical experience of individual countries indicates feasible coal phase-out rates, but can these be upscaled to the global level and accelerated by deliberate action? To answer this question, we analyse 72 national coal power p
Distribution patterns of resources and their role in determining species distribution are not only fundamental to the understanding of ecological patterns, but also of practical significance in conservation management. Shorebirds are experiencing precipitous declines globally, especially along the East Asian-Australasian Flyway (EAAF), where the major threats include the loss and degradation of ti
Tidsberoende effekter, såsom krypning, krympning och stålrelaxation, är ofta svåra att prediktera när det kommer till förspända betongkonstruktioner. Krypning som ett fenomen är komplicerat och förenklas därför i gällande byggnormer (Eurocode), för att underlätta konstruktörens arbete. När det gäller etappvis spännarmerade betongbroar har dessa förenklingar visat sig ge felaktiga prognoser av de tLong-term effects, such as creep, shrinkage, and steel relaxation, are often difficult to predict for prestressed concrete structures. Creep as a phenomenon is complicated to describe and is therefore simplified in the current building standards, to better accommodate the designer. When dealing with segmentally constructed prestressed concrete bridges, these simplifications have shown to provide i
Outside the box. On archivists' views on objects in municipal archives Historically objects in archives and objects as "documents" have been discussed for a long time. The focus of the discussion has generally been on defining what is a document, and what is not, and later what is in turn an act and thus belongs in the archive, and what does not. An object is generally not defined a
