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Catrines intressanta blekhet

Popular Abstract in Swedish Men älskar du honom? Så frågar en ung flicka på 1820-talet sin syster Henrietta som just skall gifta sig. Nej det gör Henrietta inte men hon böjer sig för den krassa verkligheten, behovet att bli försörjd. Den stillsamma frågan anger något som kan tolkas som en tyst revolution: övergången från en äldre syn på äktenskapet som ett ekonomiskt kontrakt till en uppfattning aThe main theme of this dissertation is the question of how young women in the early middle class handled the new demands for marriage based on love instead of on judgements of moral, economy and status. Another theme is the education of these middle class girls around 1800 and the question how this new education interacted with the new demands for love marriage. The German social historian Ulrike

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The objectives of this dissertation are 1) to describe what child protection services actually do when assessing risk and deciding on interventions, and 2) to analyze this practice in the light of institutional expectations, organizational demands and professional technology. The field work was carried out in two Danish municipal social service agencies. Data consist of records on families subject

Structure and Function of Odorant Binding Proteins and Chemosensory Proteins in Moths.

Odorant Binding Proteins (OBPs) and Chemosensory Proteins (CSPs) are small soluble proteins found in the lymph of insect sensillae located on insect antennae. Odorant Binding proteins are implied in olfaction, by binding hydrophobic odorant molecules and transporting them to the olfactory receptor located on the dendrite of the olfactory neurons. They are divided into three groups, Pheromone Bindi

Mannan-hydrolysis by hemicellulases: enzyme-polysaccharide interaction of a modular beta-mannanase

The enzymatic degradation of plant polysaccharides is a process of fundamental importance in nature which involves a wide range of enzymes. In this work, the structure and function of hemicellulose-degrading enzymes was investigated. The focus was on a beta-mannanase (TrMan5A) produced by the filamentous fungus Trichoderma reesei. This enzyme is composed of a catalytic module and a carbohydrate-bi

Immunoregulation in an experimental model of allergic asthma

Popular Abstract in Swedish Astma är en folksjukdom i Sverige. Mellan 5-10 % av befolkningen har astma i varierande svårighetsgrad. Förekomsten av astma är dessutom stigande – mest markant ses detta hos unga individer. Astma påverkar därför livskvaliteten hos många (däribland många barn) och hos en del utvecklas en gravt invalidiserande och ibland dödlig sjukdom. Astma kännetecknas av episoder medIn allergic asthma the immune response to antigen is inappropriate, leading to an inflammatory process in the respiratory mucosa. To further elucidate immunological mechanisms involved in the development of such inflammation, control mice and mice deficient in selected cell types or proteins, were used in experimental models of allergic asthma and anaphylaxis. The present study demonstrates that

Over-Indebtedness and Consumption Patterns in Digital Society – A Research Review

This LUii report presents a research review of the field of over-indebtedness and consumption patterns in digital society, which addresses phenomena such as e-commerce, smart phones and their role in consumption and credit, new methods of payment, debt-incurrence and more. The research review has been produced by researchers at Lund University on behalf of the Swedish Enforcement Authority, why it

Longitudinal strain from velocity encoded cardiovascular magnetic resonance: a validation study

Background: Regional myocardial function is typically evaluated by visual assessment by experienced users, or by methods requiring substantial post processing time. Visual assessment is subjective and not quantitative. Therefore, the purpose of this study is to develop and validate a simple method to derive quantitative measures of regional wall function from velocity encoded Cardiovascular Magnet

High-Dose Radioimmunotherapy Combined With Extracorporeal Depletion in a Syngeneic Rat Tumor Model

BACKGROUND: The aim of the current study was to investigate the possibility of increasing the maximal tolerated dose (MTD) of a tumor-selective radiolabeled antibody when radioimmunotherapy (RIT) is combined with extracorporeal depletion of radioimmunoconjugates from the circulation. Furthermore, the authors evaluated whether this increase in dose improved the therapeutic effect on solid manifest

Quantitative Analysis of Immune Response and Erythropoiesis during Rodent Malarial Infection

Malarial infection is associated with complex immune and erythropoietic responses in the host. A quantitative understanding of these processes is essential to help inform malaria therapy and for the design of effective vaccines. In this study, we use a statistical model-fitting approach to investigate the immune and erythropoietic responses in Plasmodium chabaudi infections of mice. Three mouse ph

Copeptin, a marker of vasopressin, in abdominal obesity, diabetes and microalbuminuria: the prospective Malmö Diet and Cancer Study cardiovascular cohort.

Background: High plasma copeptin (copeptin), the C-terminal fragment of arginine vasopressin pro-hormone, has been associated with the metabolic syndrome (MetS), diabetes mellitus (DM) development and nephropathy. Here we tested whether elevated copeptin level is associated with later development of the MetS, its individual components and microalbuminuria. Methods: We analysed copeptin at baselin

Type 2 diabetes susceptibility gene variants predispose to adult-onset autoimmune diabetes

Aims/hypothesis Latent autoimmune diabetes in adults (LADA) is phenotypically a hybrid of type 1 and type 2 diabetes. Genetically LADA is poorly characterised but does share genetic predisposition with type 1 diabetes. We aimed to improve the genetic characterisation of LADA and hypothesised that type 2 diabetes-associated gene variants also predispose to LADA, and that the associations would be s

Magnetic enhancement of Baltic Sea sapropels by greigite magnetofossils

Magnetotactic bacteria (MTB) are known to biosynthesise single-domain magnetite (Fe3O4) for geomagnetic navigation and their relict magnetosomes (called magnetofossils) can control the magnetic properties of lake and marine sediments. Magnetotactic bacteria also produce greigite (Fe3S4) magnetosomes but, compared to those made of magnetite, relatively little is known about the sedimentary environm

Albitization and quartz dissolution in Paleoproterozoic metagranite, central Sweden - Implications for the disposal of spent nuclear fuel in a deep geological repository

Hydrothermal alteration resulting in albitization and quartz dissolution has been identified in Paleoproterozoic metagranites down to - 1000 m elevation at Forsmark, Sweden. The alteration features were discovered during investigations to locate a site for the disposal of spent nuclear fuel in a deep geological repository. In general, albitization occurs extensively, but it is also observed locall

Prediction of Alzheimer's Disease Using Midregional Proadrenomedullin and Midregional Proatrial Natriuretic Peptide: A Retrospective Analysis of 134 Patients With Mild Cognitive Impairment

Objective: Development of biomarkers for early detection of Alzheimer's disease (AD) is a major clinical research goal. On the basis of the hypothesis that cardiovascular risk factors contribute to the pathogenesis of AD, we investigated whether the cardiovascular risk markers midregional proadrenomedullin (MR-proADM) and midregional proatrial natriuretic peptide (MR-proANP) predict a major clinic

50 years after - examination of some circumstances around the establishment of the correct chromosome number of man

Three authors, Levan (1975, 1978), Tjio (1978) and Hulten (2002)have independently described the establishment of the correct chromosome number of man Tjio and Levan 1956 and the background to that study. However, the three authors provide strikingly different accounts of this historical discovery. In this study I have examined the consistency between these accounts and details provided by the log

Does pond quality limit frogs Rana arvalis and Rana temporaria in agricultural landscapes? A field experiment

1. When assessing the cause of population absence or decline, it is important to understand the relative effect of local, regional and global factors. In this study we evaluated the first of these factors for two frog populations. 2. Amphibians are often absent from intensively farmed areas. There could be several reasons for this, one of them being the quality of the aquatic habitat available fo

The workplace lunchroom: an arena for multicultural eating

Many countries in Europe have experienced growing migration since World War II. It is estimated that more than one in five Swedes living today has roots in other countries and cultures. Segregation in terms of ethnic origin in housing areas makes it easier to maintain the language and cultural traditions of the home country when it comes to cooking and eating. In extremely segregated housing areas

Muscular exercise can cause highly pathological liver function tests in healthy men.

What is already known about this subject • The occurrence of idiosyncratic drug hepatotoxicity is a major problem in all phases of clinical drug development and the leading cause of postmarketing warnings and withdrawals. • Physical exercise can result in transient elevations of liver function tests. • There is no consensus in the literature on which forms of exercise may cause changes in liver

Impact of neurohormonal blockade on association between body mass index and mortality.

The prognostic impact of body mass index ( BMI) in patients following acute myocardial infarction ( AMI) may be altered by neurohormonal blockade. Methods: The impact of neurohormonal blockade on the association between BMI and mortality was examined in 5548 patients following AMI ( CONSENSUS II), 50% receiving enalapril and 7% beta- blockade, and in 4367 patients with coronary artery disease ( CA

Vitamin D receptor 3 ' haplotypes are unequally expressed in primary human bone cells and associated with increased fracture risk: The MrOS study in Sweden and Hong kong

The VDR is a prime candidate gene for osteoporosis. Here, we studied three common VDR haplotypes in relation to bone phenotypes in 5014 participants of the global MrOS Study. We also studied the relative expression of the haplotypes in human bone cells. One haplotype was associated with increased fracture risk and differently expressed in primary human bone cells. Introduction: Vitamin D plays an