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OBJECTIVES: To evaluate the impact on bone turnover of primary hyperparathyroidism (pHPT) with special reference to patients with mild pHPT, using biochemical markers of bone formation and resorption.DESIGN: A longitudinal study of patients with pHPT before and one year after surgical treatment.SETTING: The Departments of Internal Medicine and Surgery, Lund University Hospital.SUBJECTS: Forty cons

Myeloid cells play a central role in atherosclerosis. We investigated the associations between the plasma levels of growth factors and chemokines that regulate myeloid cell homeostasis and function and the risk of first-time acute coronary events in middle-aged persons. Methods and Results-We measured baseline plasma levels of macrophage colony-stimulating factor monocyte chemotactic protein 1; C-

Mechanical forces exists in many cellular processes, including cell proliferation, migration, rearrangement and differentiation. The transformation of cancer cells from normal cells, cancer metastasis and cell rearrangement during morphogenesis all involve changes in cellular mechanical forces. Although there are some studies about normal cell and cancer cell force measurements, a direct compariso

BACKGROUND The efficacy and effectiveness of the quadrivalent human papillomavirus (HPV) vaccine in preventing high-grade cervical lesions have been shown. However, data to inform the relationship between quadrivalent HPV vaccination and the subsequent risk of invasive cervical cancer are lacking. METHODS We used nationwide Swedish demographic and health registers to follow an open population of 1

Improving energy performance in the Swedish multifamily building stock is an important undertaking in order to reach national and international targets for energy efficiency. However, growing economic inequalities in Sweden, manifested in the multifamily building stock as housing inequalities that entail segregation, overcrowding, and differences in standard of living, have led to low-income house

Pollination is a key ecosystem service for global agriculture but evidence of pollinator population declines is growing. Reliable spatial modelling of pollinator abundance is essential if we are to identify areas at risk of pollination service deficit and effectively target resources to support pollinator populations. Many models exist which predict pollinator abundance but few have been calibrate

Attention Restoration Theory point to nature as a particularly good candidate for restoring the ability to focus and inhibit distractions. However, little effort has been directed to elaborating on what makes nature's visual pattern unique for restoration purposes. One suggested explanation is the fractal properties of natural patterns (Hagerhall, 2005). Both perception studies (Hagerhall et al.,

Can law still play a central role in governing human behavior even if the state law may have become less important? Whether law without the state is possible depends, of course, on how we define “law” and “state”. But it also depends on the perspective from which one approaches the legal material. From a sociology of law perspective, as will be presented in this chapter, the topic has a slightly d

In diffusion MRI (dMRI), microscopic diffusion anisotropy can be obscured by orientation dispersion. Separation of these properties is of high importance, since it could allow dMRI to non-invasively probe elongated structures such as neurites (axons and dendrites). However, conventional dMRI, based on single diffusion encoding (SDE), entangles microscopic anisotropy and orientation dispersion with

Plant-feeding insects reduce yields substantially in all major crops despite considerable crop protection efforts. A lack of long-term monitoring data and insufficient ecological knowledge of pest insects limit our possibilities to characterize drivers of change in their abundances. We demonstrate how a suite of complementary methods and data sources can be used to analyse historical shifts in pes

The objective of this paper is to report the effects that control/operational strategies may have on plant-wide phosphorus (P) transformations in wastewater treatment plants (WWTP). The development of a new set of biological (activated sludge, anaerobic digestion), physico-chemical (aqueous phase, precipitation, mass transfer) process models and model interfaces (between water and sludge line) wer

This thesis presents the study of a position-sensitive scintillation-based detector called the Solid-State Neutron Detector (SoNDe). SoNDe is being developed for cold- and thermal-neutron detection at the small-angle neutron scattering (SANS) instrument SKADI at the European Spallation Source (ESS), currently under construction in Lund, Sweden. The response of the detector scintillator, multi-anod

Plants release to the atmosphere reactive gases, so-called volatile organic compounds (VOCs). The release of VOCs from vegetation is temperature-dependent and controlled by vegetation composition because different plant species release a distinct blend of VOCs. We used modelling approaches on ecosystem VOC release data collected across the Arctic, which is experiencing both rapid warming and veget

Background: Monte Carlo simulations provide accurate models of nuclear medicine imaging systems as they can properly account for the full physics of photon transport. The accuracy of the model included in the maximum-likelihood–expectation-maximization (ML-EM) reconstruction limits the overall accuracy of the reconstruction results. In this paper, we present a Monte Carlo-based ML-EM reconstructio

Relative free energies for the binding of nine cyclic carboxylate ligands to the octa-acid deep-cavity host were calculated at the combined density-functional theory and molecular mechanics (DFT/MM) level of theory. The DFT calculations employed the BLYP functional and the 6-31G∗ basis set for the ligand. We employed free-energy perturbations (FEP) with the reference-potential approach and used m

Popular Abstract in Swedish Förbättrad effektivitet i tillverkningssystemen för att åstadkomma förbättrad output och sålunda reducera tillverkningsstörningarna är ett viktigt område. Händelsestyrd simulering kan visualisera och studera de dynamiska förloppen relaterade till total effektivitet i tillverkningssystemen. En metodik för reducering av produktionsstörningar är presenterad. Förbättringar Improved efficiency in manufacturing systems to achieve increased output and thus reduced production disturbances is a vital area. DES (Discrete-Event Simulation) can visualize and study the dynamic issues related to total efficiency in manufacturing systems. A methodology for production disturbance reduction is presented. Increased performance of manufacturing systems means not only enhanced valu

In Sweden during the 1940s and 50s, many artistically ambitious filmmakers, like Arne Sucksdorff, Gösta Werner, and Peter Weiss, sought and gained financial aid from sponsors within the industry. Whereas many sponsored films document and communicate industrial processes, these films are more creatively oriented and experiment with film as an artistic expression. Although economic concerns undoubte

Background: The widespread use of relative scales in socioepidemiological studies has recently been criticized. The criticism is based mainly on the fact that the importance of different risk factors in explaining social inequalities in cardiovascular disease (CVD) varies, depending on which scale is used to measure social inequalities. The present study examines the importance of established risk

The influence of exciton-vibrational coupling on the optical and transport properties of molecular aggregates is an old problem that gained renewed interest in recent years. On the experimental side, various nonlinear spectroscopic techniques gave insight into the dynamics of systems as complex as photosynthetic antennae. Striking evidence was gathered that in these protein-pigment complexes quant