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Right ventricular remodeling after conduit replacement in patients with corrected tetralogy of Fallot - Evaluation by cardiac magnetic resonance

Purpose: To evaluate the potential for right ventricular reverse remodelling after pulmonary valve replacement using cardiac magnetic resonance imaging, in adults with corrected tetralogy of Fallot and severe pulmonary insufficiency. Material and methods: Ten patients with previous correction of tetralogy of Fallot with severe pulmonary insufficiency accepted for pulmonary valve replacement were

The correlation between regulatory conditions and antibiotic consumption within the WHO European Region

Background: In a global perspective, bacterial infections are still a major cause of morbidity and mortality; therefore, effective antibiotics are needed. However, the emergence of antibiotic resistance due to irrational use has now become a serious public health problem. Hence, the objective of this study was to analyse the association of regulatory aspects with antibiotic consumption. Methods: A

Recall and perceived naturalness of asynchronous speech and gesture

Part of the justification for an integrated view of speech and gestures ( (( is their temporal coordination. Gestures generally coincide with or precede, but rarely follow lexical affiliate (McNeill, 1992). How synchrony impacts listeners remains less explored, despite potential relevance for video communication and virtual conversational agents. ERP studies suggest that temporal alignment affects

Reporting of complex interventions in clinical trials : Development of a taxonomy to classify and describe fall-prevention interventions

Interventions for preventing falls in older people often involve several components, multidisciplinary teams, and implementation in a variety of settings. We have developed a classification system (taxonomy) to describe interventions used to prevent falls in older people, with the aim of improving the design and reporting of clinical trials of fall-prevention interventions, and synthesis of eviden

Associations between neurodevelopmental disorders and factors related to school, health, and social interaction in schoolchildren : Results from a Swedish population-based survey

Background Children and adolescents with autism spectrum disorder (ASD) or attention-deficit/hyperactivity disorder (ADHD) are more likely to be surrounded by different risk factors. In order to work preventively with decreasing ADHD and ASD symptoms, there is a need of more knowledge concerning risk factors. Objective This study aimed to investigate school, health, lifestyle and social interactio

Capto™ Resins for Chromatography of DNA : A Minor Difference in Ligand Composition Greatly Influences the Separation of Guanidyl-Containing Fragments

The differences in chromatographic behaviour of individual deoxynucleotides as well as small single-stranded and double-stranded DNA molecules have been examined for two resins from the Capto family: Capto Adhere and Capto Q ImpRes. Capto Adhere carries a multimodal ligand which combines strong anion with aromatic recognition, while Capto Q ImpRes is a strong anion exchanger with a chemically simi

HOXC8 regulates self-renewal, differentiation and transformation of breast cancer stem cells

Background: Homeobox genes are master regulators of cell fate during embryonic development and their expression is altered in cancer. By regulating the balance between cell proliferation and differentiation, they maintain homeostasis of normal tissues. Here, we screened the expression of homeobox genes in mammary stem cells to establish their role in stem cells transformation in breast cancer. Met

Comparative system identification of flower tracking performance in three hawkmoth species reveals adaptations for dim light vision

Flight control in insects is heavily dependent on vision. Thus, in dim light, the decreased reliability of visual signal detection also prompts consequences for insect flight. We have an emerging understanding of the neural mechanisms that different species employ to adapt the visual system to low light. However, much less explored are comparative analyses of how low light affects the flight behav

An Investigation on Ignition-Delay Modelling for Control

The ignition delay is an important quantity in low temperature combustion concepts where a prolonged ignition delay gives an enhanced fuel-air mixing process, favorable for decreased particulate and NOx emission levels. This article investigates three different low-order physics-based correlation models and their ability to predict the ignition delay for the purpose of model-based controller desig

Prioritization guidelines for green food packaging development

Purpose: Current literature emphasizes using a holistic perspective on green packaging development (GPD) as an important strategy for reducing the environmental impact of products’ supply chain (SC). In practice, however, it can be difficult for packaging developers to strike a balance between all the different environmental requirements on packaging, and trade-offs are common. Life cycle assessme

A mitochondrial implication in a Tunisian patient with Friedreich's ataxia-like

Genes encoding the DNA helicase TWINKLE (C10orf2) or the two subunits of mtDNA polymerase γ (POLγ) (POLG1 and POLG2) have a direct effect on the mitochondrial DNA replication machinery and were reported in many mitochondrial disorders. Friedreich's ataxia (FRDA) is the common cause of ataxia often associated with the expansion of a GAA repeat in intron 1 of the frataxin gene (FXN). Mitochondrial D

High folate intake is associated with lower breast cancer incidence in postmenopausal women in the Malmö Diet and Cancer cohort

BACKGROUND: Epidemiologic studies of associations between folate intake and breast cancer are inconclusive, but folate and other plant food nutrients appear protective in women at elevated risk.OBJECTIVE: The objective was to examine the association between folate intake and the incidence of postmenopausal breast cancer.DESIGN: This prospective study included all women aged >or=50 y (n = 11699) fr

Being a homebirth midwife in the Nordic countries - a phenomenological study

OBJECTIVE: To describe the lived experience of being a homebirth midwife in the Nordic countries.METHODS: Interviews conducted with 21 homebirth midwives from the five Nordic countries were analyzed with a phenomenological approach.RESULTS: The essential structure of being a homebirth midwife in the Nordic countries can be understood as realizing altruistic values and fulfilling one's own desires

Luminescence dating of aeolian–coastal events on the Kristianstad plain, SE Sweden

Aeolian–coastal sediments and landforms are excellent palaeoenvironmental archives, but chronological studies of coastal records are scarce in Sweden. In this study, we provide luminescence and radiocarbon ages of aeolian activity and coastal landscape evolution on the Kristianstad plain, SE Sweden, based on the investigations of two foredunes and two inland dunes at Åhus and Vittskövle. Additiona

The association between adult attained height and sitting height with mortality in the European prospective investigation into cancer and nutrition (EPIC)

Adult height and sitting height may reflect genetic and environmental factors, including early life nutrition, physical and social environments. Previous studies have reported divergent associations for height and chronic disease mortality, with positive associations observed for cancer mortality but inverse associations for circulatory disease mortality. Sitting height might be more strongly asso

Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers

More than 20 genetic loci have been associated with risk for Alzheimer’s disease (AD), but reported genome-wide significant loci do not account for all the estimated heritability and provide little information about underlying biological mechanisms. Genetic studies using intermediate quantitative traits such as biomarkers, or endophenotypes, benefit from increased statistical power to identify var

Risk of pulmonary embolism and deep venous thrombosis in patients with asthma : A nationwide case-control study from Sweden

Asthma is associated with an increased risk of pulmonary embolism (PE) but little is known about whether asthma is associated with an increased risk of deep venous thrombosis (DVT). The aim in this study was to determine the risk of the first event of PE, DVT or a combination of PE and DVT in patients with asthma. We conducted this nationwide case-control study using data from Swedish nationwide r

Impact study of the climate change on the energy performance of the building stock in Stockholm considering four climate uncertainties

This work describes the research conducted in order to assess possible changes and uncertainties in future energy performance of the residential building stock in Stockholm. The investigation is performed on a sample of 153 existing and statistically selected buildings and covers the period of 1961-2100. Four uncertainty factors of the climate have been considered: global climate models, regional

Changes in the Personal Networks of Young Immigrants in Sweden

In this chapter, we focus on the social integration of young immigrants in Sweden who themselves and/or one or both of their parents came from Iran or former Yugoslavia. In particular, we look at the share of alters in their core networks who are of the same parental national origin and how this has changed within a period of four years. To explain network changes, we consider the parental nationa

Chronic musculoskeletal pain predicted hospitalisation due to serious medical conditions in a 10 year follow up study

BACKGROUND: The aim was to examine if self reported chronic regional pain (CRP) and chronic widespread pain (CWP) predicted inpatient care due to serious medical conditions such as cerebrovascular diseases, ischemic heart diseases, neoplasms and infectious diseases in a general population cohort over a ten year follow-up period.METHODS: A ten-year follow up of a cohort from the general adult popul