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Comparative immunomodulatory effects in mice and in human dendritic cells of five bacterial strains selected for biocontrol of leafy green vegetables

The market for ready-to eat vegetables is increasing, but unfortunately so do the numbers of food-borne illness outbreaks related to these products. A previous study has identified bacterial strains suitable for biocontrol of leafy green vegetables to reduce the exposure to pathogens in these products. As a tentative safety evaluation, five selected strains (Rhodococcus cerastii MR5x, Bacillus coa

Molecular Imaging for Localized Prostate Cancer: Analysis of 2 Prospective Phase 0 Trials of PSMA Targeted Immuno-PET and –SPECT, and Implications for the Radiation Oncologist

Purpose/Objective(s): To report the efficacy and utility of PSMA-based molecular targeted imaging in localized prostate cancer using 111In-J591 SPECT and 89Zr-J591 immuno-PET.Materials/Methods: Initiated in 2010, two sequential phase 0 prospective studies were performed on a total of 19 patients evaluating the roles of 111In-J591 SPECT and 89Zr-J591 immuno-PET. All patients had a baseline MRI foll

Current knowledge and uncertainties associated with the Arctic greenhouse gas budget

• The Arctic is continuing to warm faster than any other region on Earth, but key uncertainties remain in our knowledge of the Arctic carbon cycle. • We review the most current knowledge pertaining to estimates of arctic greenhouse gas components and discuss uncertainties associated with these measurements and models. • While the Arctic Ocean is consistently estimated as a carbon sink, we have yet

Judges Assessing the Independence of Judges. Historical Foundations and Practical Procedures in Facing the Threats against the Rule of Law in Europe

The existence of impartial and independent courts is a cornerstone of the success of the European project. The recent renaissance of “illiberal States” jeopardises the application of the rule of law and risks destroying the foundations of the EU legal order. In 2018, the Court of Justice of the European Union (CJEU) began developing two new lines of case-law. Firstly, the CJEU found itself to be c

Effects of print orientation on the design of additively manufactured bio-based flexible lattice structures

In upholstery applications, it is common to use polyurethane (PUR) foam when flexibility is desired. However, as PUR is a carbon-based material produced using toxic isocyanates, it is environmentally beneficial to replace PUR with bio-based alternatives. The challenge, however, lies in finding suitable bio-based replacement materials, capable of mimicking the foam-like functionality of PUR since m

A pilot study of methods for prediction of poor outcome by head computed tomography after cardiac arrest

Introduction: In Sweden, head computed tomography (CT) is commonly used for prediction of neurological outcome after cardiac arrest, as recommended by guidelines. We compare the prognostic ability and interrater variability of routine and novel CT methods for prediction of poor outcome. Methods: Retrospective study including patients from Swedish sites within the Target Temperature Management afte

Patterns of Communication About Serious Illness in the Years, Months, and Days before Death

Background: Communication with patients and families about serious illness impacts quality of life and helps facilitate decision-making.Objective: To elucidate the pattern of communication about serious illness for patients who have died in an inpatient setting.Design: Three hundred patients from the Swedish Registry of Palliative Care 2015-2017 were randomly selected for manual chart review.Setti

A Reduced Deck of Conversation Cards of Wishes and Priorities of Patients in Palliative Care

The individual wishes and priorities of patients with advanced disease are too often neglected, making a deck of cards with statements reflecting potential wishes and priorities a useful conversation tool. However, in the most ill patients, the card selection and sorting process may be too strenuous. The aims of this study were to explore the wishes and priorities of patients receiving palliative

Family cohesion predicts long-term health and well-being after losing a parent to cancer as a teenager : :A nationwide population-based study

Background:Parentally bereaved children are at increased risk of negative consequences, and the mediating factors most consistently identified are found to be related to family function after the loss, including cohesion. However, existing evidence is limited, especially with respect to children and youths’ own perception of family cohesion and its long-term effects on health and well-being. There

Test Scheduling for 3D Stacked ICs under Power Constraints

This paper addresses Test Application Time (TAT) reduction for core-based 3D Stacked ICs (SICs). Applying traditional test scheduling methods used for non-stacked chip testing where the same test schedule is applied both at wafer test and at final test to SICs, leads to unnecessarily high TAT. This is because the final test of 3D-SICs includes the testing of all the stacked chips. A key challenge

Dynamic Logics for Threshold Models and their Epistemic Extension

We take a logical approach to threshold models , used to study the diffusion of e.g. new technologies or behaviors in social net-works. In short, threshold models consist of a network graph of agents connected by a social relationship and a threshold to adopt a possibly cascading behavior. Agents adopt new behavior when the proportion of their neighbors who have already adopted it meets the thresh

By Torches, Bones, and Temples : Material Metonyms in Personal Oaths in Latin Literature

Oath-taking during Roman Antiquity constitutes a telling example of how words and matter interplay and relate to one another. Ancient Latin literature provides a myriad of representations of oaths sworn, both fictive and supposedly historical, where matter somehow figure in the procedure. In this study, a selection of personal oaths from Roman literature are explored in terms of materiality and ag

Continuous quality assurance and ML pipelines under the AI Act

More than ever, Machine Learning (ML) as a subfield of Artificial Intelligence (AI) is on the rise and is finding its way into safety-critical software applications. However, when it comes to quality assurance (QA) and trustworthiness, integrating ML models into software comes with challenges that may not be apparent at first glance. The European Union (EU) aims to tackle this problem with new reg

Value of Seismic Structural Health Monitoring Information for Management of Civil Structures Under Different Prior Knowledge Scenarios

Seismic Structural Health Monitoring (S2HM) provides information about the integrity of civil structures and infrastructure in the aftermath of an earthquake. However, quantifying the benefits of S2HM information is crucial to justify the investment in S2HM systems. The benefit of S2HM can be computed through the Value of Information (VoI) from Bayesian decision theory, which compares the expected

Housing accessibility and its associations with participation among older adults living with long-standing spinal cord injury

Objectives: To describe the housing situation and aspects of participation among older adults living with long-standing spinal cord injury (SCI) with attention to SCI severity, and to examine whether and how objective housing accessibility (based on objectively measurable criteria) is associated with aspects of participation. Design: Cross-sectional study utilizing the assessment tools Impact on P