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Epitope shift of proteinase-3 anti-neutrophil cytoplasmic antibodies in patients with small vessel vasculitis.

Summary Anti-neutrophil cytoplasmic antibodies against proteinase 3 (PR3-ANCA) are used as diagnostic tools for patients with small vessel vasculitis (AASV). We have produced chimeric mouse/human PR3 molecules and investigate changes in reactivity over time and the possible relationship between epitope specificity and clinical course. Thirty-eight PR3-ANCA-positive patients diagnosed between 1990

Ny strategi för vetenskaplig bokpublicering vid Lunds universitet

Två förslag till en bättre publiceringsverksamhet vid Område HT och vid Lunds universitet. Rapport från projektet HT-områdets bokpubliceringar. Rapporten innehåller förutom de två förslagen också kort historisk bakgrund, nationell och skandinavisk jämförelse och inventering av HT-forskarnas publiceringar. Dessutom sammanfattas två väsentliga internationella diskussioner: hur universitetsförlagen

Changing minds by tracking eyes: Dynamical systems, gaze and moral decisions

Decision making is a dynamic process. Alternatives compete over time, and this competition plays out in sensorimotor processes. This is true not just for perceptual decisions or simple categorisation tasks, but also for moral decisions, which are the outcome of a complex interplay of intuition, emotion and reasoning. In this experiment, we first establish a descriptive and causal link between gaze

Remote fluorescence lidar imaging of monuments: the Coliseum and the Lateran Baptistery in Rome

On site remote laser-induced fluorescence measurements have been performed with application towards non-movable objects. This paper describes the application of non-invasive hyperspectral fluorescence imaging to two masonry monuments, the Coliseum and the Lateran Baptistery in Rome, during a joint Italian-Swedish experiment. The mobile systems of Lund Institute of Technology, Sweden, and CNR-IFAC,

On the convergence rate of the dirichlet-neumann iteration for coupled poisson problems on unstructured grids

We consider thermal fluid structure interaction with a partitioned approach, where typically, a finite volume and a finite element code would be coupled. As a model problem, we consider two coupled Poisson problems with heat conductivities $$\lambda _1$$, $$\lambda _2$$ in one dimension on intervals of length $$l:1$$ and $$l:2$$. Hereby, we consider linear discretizations on arbitrary meshes, such

Kampen om historien - Ådalen 1931 - Sociala konflikter, historiemedvetande och historiebruk 1931-2000

Popular Abstract in Swedish Det finns en skillnad mellan historia som vetenskap och historia som historiskt minne, som boken vill fästa uppmärksamhet på. Ådalen som motbild till det trygga Folkhemmet är en bild av hur vi kan uppleva verkligheten. Inte nödvändigtvis hur den såg ut. Vår uppfattning om vad som hänt kan vaa nog så verklig när vi handlar, agerar och tolkar omvärlden. Det är denna tolknThe prelude to this thesis is provided by the dramatic scenes that took place in Ådalen. During a demonstration, four men and one young woman were shot to death and five others injured by military troops ordered to Lunde harbour. Inspired by a number of other researchers (Koselleck, Samuel, Somers, Stråth, Södring, Jensen and Burke, to name a few), my investigation has analysed how the story of th

Who controls logistics emissions? Challenges in making fragmented supply chains environmentally sustainable from a logistics service provider's perspective

Purpose The purpose of this article is to explore the environmental impact of Logistics Service Provider (LSP) activities in the light of increased customer attention and fragmentation of the industry. We try to answer the question, to what extent the LSPs can actually monitor the environmental impact of logistics activities in the supply chain? Design/methodology/approach The methodology of this

Auschwitz, autenticitet, kunskap

This essay reflects on issues surrounding the remembrance and teaching of the Holocaust. It was commissioned by the project Living History and the Swedish Prime Minister's Office.

Interaction Ecologies

In this paper we present one approach to understand palpability from the perspective of eco-systems of palpable devices. We will introduce the notion of Palpable Interaction Ecology that particular focus upon the properties that emerge from the interaction between people, their practices and palpable devices. This approach is derived from research into the use of pervasive healthcare services that

SVARNE - an expert system based on tacit knowledge

The SVARNE project investigates how an expert system may be used when dealing with occurrences of violence within the care of people with cognitive impairments. The method used is potentially applicable in many other areas where the expert knowledge is ma

Monoclonal antibodies to the pituitary growth-hormone receptor by the anti-idiotypic approach. Production and initial characterization

We obtained 10/192 and 3/384 antibody-secreting hybrids after immunization of Balb/c mice with either human growth hormone or affinity-purified rabbit anti-(human growth hormone) respectively. Radiolabelled rabbit anti-(human growth hormone) antibodies, but not human growth hormone, were specifically bound by supernatants from the 13 hybrids. The binding was completely inhibited by human-growth-ho

Frame disputes or frame consensus? "environment" or "welfare" first amongst climate strike protesters

Present debates suppose a close linkage between economic, social, and environmental sustainability and suggest that individual wellbeing and living standards need to be understood as directly linked to environmental concerns. Because social movements are often seen as an avant-garde in pushing for change, this article analyzes climate protesters' support for three key frames in current periods of

Aligning research with policy and practice for sustainable agricultural land systems in Europe

Agriculture is widely recognized as critical to achieving the Sustainable Development Goals (SDGs), but researchers, policymakers, and practitioners have multiple, often conflicting yet poorly documented priorities on how agriculture could or should support achieving the SDGs. Here, we assess consensus and divergence in priorities for agricultural systems among research, policy, and practice persp

From Epipalaeolithic petroglyphs to Roman graffiti : Stylistic variability of anthropomorphs at Gebel el Silsila (Upper Egypt)

Gebel el-Silsila displays an astounding concentration of incised illustrations, of which anthropomorphic figures are frequent motifs. These figures were produced over several millennia; from prehistoric petroglyphs to pictorial graffiti of dynastic periods and throughout into Roman days. Spanning over six millennia visitors to Gebel el Silsila depicted huntsmen, warriors, boatmen, and horsemen, reGebel el Silsila displays an astounding concentration of incised illustrations, of which anthropomorphic figures are frequent motifs. These figures were produced over several millennia: from prehistoric petroglyphs to pictorial graffiti of dynastic periods and throughout into Roman days. Spanning over six millennia visitors to Gebel el Silsila depicted huntsmen, warriors, boatmen, and horsemen, re

Geospatial data integration and visualisation using Linked Data

Geospatial data are increasingly available nowadays, and this leads to more analyses and visualisation of geospatial data from several sources. To enable this, we need homogenous data as well as proper integration methods. Geospatial data integration has been a longstanding research topic for decades, and this paper discusses the utilisation of Linked Data technology stack to alleviate the geospat

Extreme diversification of floral volatiles within and among species of Lithophragma (Saxifragaceae)

A major challenge in evolutionary biology is to understand how complex traits of multiple functions have diversified and codiversified across interacting lineages and geographic ranges. We evaluate intra- and interspecific variation in floral scent, which is a complex trait of documented importance for mutualistic and antagonistic interactions between plants, pollinators, and herbivores. We perfor