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Aligning research with policy and practice for sustainable agricultural land systems in Europe

Agriculture is widely recognized as critical to achieving the Sustainable Development Goals (SDGs), but researchers, policymakers, and practitioners have multiple, often conflicting yet poorly documented priorities on how agriculture could or should support achieving the SDGs. Here, we assess consensus and divergence in priorities for agricultural systems among research, policy, and practice persp

Metabolic engineering of Thermoanaerobacterium AK17 for increased ethanol production in seaweed hydrolysate

Sustainably produced renewable biomass has the potential to replace fossil-based feedstocks, for generation of biobased fuels and chemicals of industrial interest, in biorefineries. In this context, seaweeds contain a large fraction of carbohydrates that are a promising source for enzymatic and/or microbial biorefinery conversions. The thermoanaerobe Thermoanaerobacterium AK17 is a versatile ferme

Models of our Galaxy - II

Stars near the Sun oscillate both horizontally and vertically. In a previous paper by Binney it was assumed that the coupling between these motions can be modelled by determining the horizontal motion without reference to the vertical motion, and recovering the coupling between the motions by assuming that the vertical action is adiabatically conserved as the star oscillates horizontally. Here, we

Monoclonal antibodies to the pituitary growth-hormone receptor by the anti-idiotypic approach. Production and initial characterization

We obtained 10/192 and 3/384 antibody-secreting hybrids after immunization of Balb/c mice with either human growth hormone or affinity-purified rabbit anti-(human growth hormone) respectively. Radiolabelled rabbit anti-(human growth hormone) antibodies, but not human growth hormone, were specifically bound by supernatants from the 13 hybrids. The binding was completely inhibited by human-growth-ho

Versatility of multivalent orientation, inverted meiosis, and rescued fitness in holocentric chromosomal hybrids

Chromosomal rearrangements (e.g., fusions/fissions) have the potential to drive speciation. However, their accumulation in a population is generally viewed as unlikely, because chromosomal heterozygosity should lead to meiotic problems and aneuploid gametes. Canonical meiosis involves segregation of homologous chromosomes in meiosis I and sister chromatid segregation during meiosis II. In organism

Numerical investigations of endwall film cooling design of a turbine vane using four-holes pattern

Purpose: Endwall film cooling protects vane endwall by coolant coverage, especially at the leading edge (LE) region and vane-pressure side (PS) junction region. Strong flow impingement and complex vortexaa structures on the vane endwall cause difficulties for coolant flows to cover properly. This work aims at a full-scale arrangement of film cooling holes on the endwall which improves coolant effi

Blood-based mitochondrial respiratory chain function in major depression

Mitochondrial dysfunction has been implicated in major depressive disorder (MDD). A measure of mitochondrial respiratory chain (RC) enzymatic activity—the Mitochondrial Health Index (MHI)—has previously been found to correlate with stress and emotional states in caregivers. We here report mitochondrial RC activities, mitochondrial DNA copy number (mtDNAcn), and the composite MHI in unmedicated and

An intermediate-band photometric study of the "globular cluster" NGC 2419

NGC 2419 is one of the remotest star clusters in the Milky Way halo and its exact nature is yet unclear. While it has traits reminiscent of a globular cluster, its large radius and suggestions of an abundance spread have fueled the discussion about its origin in an extragalactic environment, possibly the remnant of the accretion of a dwarf galaxy. Here, we present first results from deep intermedi

Seasonal dynamics of haemosporidian (Apicomplexa, Haemosporida) parasites in house sparrows Passer domesticus at four European sites : comparison between lineages and the importance of screening methods

Infectious diseases often vary seasonally in a predictable manner, and seasonality may be responsible for geographical differences in prevalence. In temperate regions, vector-borne parasites such as malaria are expected to evolve lower virulence and a time-varying strategy to invest more in transmission when vectors are available. A previous model of seasonal variation of avian malaria described a

Improving musculoskeletal health for children and young people – A ‘call to action’

This chapter describes the musculoskeletal (MSK) context in children and young people as an important contributor to the global non-communicable disease burden. Through selected MSK conditions, we describe the impact on patients, families and communities and highlight the challenges that need to be addressed. We focus on opportunities for better working together and describe exemplar initiatives t

Inhibition of the serine protease HtrA1 by SerpinE2 suggests an extracellular proteolytic pathway in the control of neural crest migration

We previously showed that SerpinE2 and the serine protease HtrA1 modulate fibro-blast growth factor (FGF) signaling in germ layer specification and head-to-tail development of Xenopus embryos. Here, we present an extracellular proteolytic mechanism involving this serpin-protease system in the developing neural crest (NC). Knockdown of SerpinE2 by injected antisense morpholino oligonucleotides did

L1-orienterad grammatikundervisning i L2-kontext : En kvalitativ studie

Artikeln beskriver hur en grammatikdidaktisk modell utformad för en L1-kontext kan användas för grammatikundervisning såväl som för ett språk- och skrivutvecklande arbete i en L2-kontext. Eftersom klassrummen i Sverige, Danmark och Norge allt mer blir språkligt heterogena behöver lärare kunna erbjuda en språkutvecklande under-visning för elever med skilda språkliga förutsättningar. Den modell som The article shows how a grammar-didactic model designed for an L1 context can be used for grammar learning as well as language and writing development in an L2 con-text. Because classrooms in Sweden, Denmark and Norway are becoming increasingly heterogenous, teachers must be able to develop the language of pupils with differing linguistic predispositions. The model that is being proposed is design

Contusion expansion, low platelet count and bifrontal contusions are associated with worse patient outcome following traumatic brain injury—a retrospective single-center study

Background: Cortical contusions are common in moderate-severe traumatic brain injury (TBI). Cortical contusions often expand, potentially causing neuro-worsening several hours to days post-trauma. While contusion expansion (CE) may affect outcome, potential clinical and radiological markers that can predict CE have been insufficiently explored. In the present single-center retrospective observatio

Surrogate measures of safety : Site-based observations

Traditionally, traffic safety is expressed through the number of accidents (crashes) or people injured, since these are the most direct manifestations of an unsafe traffic environment. As we discuss in this chapter, such an approach has its limitations due to the low frequency of accidents and some other issues. Neither is it unusual that accident data is not available, not reliable or lacks impor

Making Virtual Internationalization Work Across Disciplines : The Role of University Leaders

Universities have long used internationalization to prepare students for a highly interconnected world. Although internationalization has often been associated with mobility, current calls for equity, diversity, and inclusion, and climate consciousness, among other things, require institutions to change this strategy. As a response, curriculum internationalization emerges as a more inclusive and s