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The recent progress in our work to implement salt (NaCl) as a dosemeter is presented. Laboratory investigations have indicated a linear dose response from 1 mGy to about 100 mGy and detection limits down to 0.1 mGy. Investigations in the clinic comparing TL-dosimetry in LiF and OSL in NaCl have indicated a similar dose response for the two dosemeters at different photon energies. Field studies wit
The infrared spectrum of water, isolated in inert matrices, has been studied in the interval from 60 to 4000 cm(-1). Experiments with partially deuterated water combined with DFT (density functional theory) calculations have been used to investigate the structure of matrix-isolated water tetramer. A few, strong intermolecular fundamentals of the water tetramer have been observed. Mid-infrared band
Proteus mirabilis bacilli play an important role in human urinary tract infections, bacteremia, and rheumatoid arthritis. The authors previously studied human complement C3 conversion by smooth-form P. mirabilis O10, O23, O30, and O43 lipopolysaccharides (LPSs) and showed that smooth Proteus LPSs fragmented C3 in a dose- and time-dependent manner. In the present study, one smooth P. mirabilis S195
Here a synthesis of novel galactose-1,2,3-triazole conjugates is described. The title compounds were obtained from 3-azido-3-deoxy-1,2: 5,6-di-O-isopropylidene-α-D-galactofuranose via a copper catalyzed azide-alkyne 1,3-dipolar cycloaddition reaction. It was demonstrated that the title compounds in their isopropylidene-protected form tend to chelate copper. The copper content can be diminished to
Antibody-based microarrays is a novel technology with great promise for high-throughput proteomics. The process of designing high-performing arrays has, however, turned out to be challenging. Here, we have designed the next generation of a human recombinant scFv antibody microarray platform for protein expression profiling of nonfractionated biotinylated human plasma and serum proteomes. The setup
Multimeric lactosides based on carbohydrate scaffolds with valencies ranging from 1 to 4 and different linker lengths were synthesized by a copper-catalyzed azide-alkyne cycloaddition (CuAAC). The binding affinities and crosslinking abilities of the new "click clusters" toward biologically relevant galectins (gal-1, gal-3) and peanut lectin were evaluated by fluorescent polarization assay (FPA) an
We are living in a highly dynamic, human-dominated Earth System in which non-linear, abrupt and irreversible changes are not only possible but also probable. These changes require institutional structures capable of steering human society away from critical tipping points and irreversible change and ensuring sustainable livelihoods for all. We see 2012 as a charter moment, a historic opportunity t
Tasquinimod (a quinoline-3-carboxyamide) is a small molecule immunotherapy with demonstrated effects on the tumor microenvironment (TME) involving immunomodulation, anti-angiogenesis and inhibition of metastasis. A target molecule of tasquinimod is the inflammatory protein S100A9 which has been shown to affect the accumulation and function of suppressive myeloid cell subsets in tumors. Given the m
According to medieval canon law, a marriage could be declared invalid if the consent had been given through force or fear. This ruling was a natural consequence of the insistence on free consent as the only requirement for a valid marriage. It did, however, entail a number of both practical and theoretical problems. It could be difficult to prove force and fear within the family, but also to defin
Popular Abstract in Swedish Jordens dotter. Selma Lagerlöf och den tyska hembygdslitteraturen. Avhandlingen undersöker mottagandet av Selma Lagerlöfs verk i Tyskland åren runt sekelskiftet 1900. Selma Lagerlöf introducerades på den tyska bokmarknaden 1896 med en översättning av debutverket Gösta Berlings saga. Redan tidigt under sin litterära karriär uppmärksammades hon i tysk press och nådde på This dissertation studies the reception of the works of the Swedish author Selma Lagerlöf in Germany at the turn of the century 1900. Selma Lagerlöf was introduced into the German book market in 1896, with a translation of her first novel, “The Saga of Gosta Berling”. She was well received by the German press and had after only a couple of years managed to get herself an impressive readership, whi
‘The Nurse in Primary Health Care with Special Focus on Child Health Care’ The function of nurses in Swedish primary care involves health care and medical care for people of all ages, and in their health-promotion work there is a focus on child health care. Child health care in Sweden is mostly provided by nurses. The work encompasses all children from birth to school age; it is voluntary and fre
Popular Abstract in Swedish Det finns i Sverige idag över 100 000 personer vilka överlevt insjuknande i stroke (blodpropp eller blödning i hjärnan). Varje år inträffar ca 20 000 ? 25 000 nyinsjuknanden och ca 5 000 - 10 000 återinsjuknanden i stroke. Vanliga symtom både vid det akuta insjuknandet, och senare efter genomgången akutsjukvård och rehabilite-ring, är förlamningar, talrubbningar, sväljnThe aims were to follow stroke patients over time with respect to general pain, shoulder pain, weight loss, and health related quality of life (HRQOL), the latter also in stroke survivors' informal caregivers. Methods During a 1 year period, 416 first-ever stroke patients were included in the population based Lund Stroke Register; 327 survivors were followed up after four months and 305 one year
During atrial fibrillation (AF), time-frequency analysis of atrial signal has been applied to describe fibrillatory frequency trends. Recently, temporal changes in spectral shape have been investigated using the spectral profile technique. This profile is computed recursively by fitting each short-time log-spectrum to a spectral template, using amplitude scaling and frequency shifting. The purpose
The concentrations of water dimer are compared in Ne and p-H-2 matrices at low temperatures, using infrared spectroscopy. Additional data are given for o-D-2 and Ar matrices. For a given monomer concentration, the dimer concentration is significantly higher in solid Ne (or Ar) than in solid p-H-2. In p-H-2, the dimer concentration is only slightly higher than expected for a random distribution of
Aktuell status för dagvattenhantering i grannstäderna Köpenhamn och Malmö studerades med avseende på befintliga åtgärder och genomförda systemen i de båda städerna. Tillämpning av blå-gröna lösningar i de yttre delarna av Malmö började på 1990-talet och följaktligen är samarbete mellan olika avdelningar inom kommunen mer strukturerat i Malmö medan processen i Köpenhamn fortfarande är baserad på trThe current status of storm-water management in the neighbor cities of Copenhagen and Malmö was studied with respect to present measures and the implemented systems in both cities. Application of blue-green solutions in the outer parts of Malmö started in the 1990s; hence collaboration between different departments in the municipality is more structured in the city of Malmö while in Copenhagen the
Brachytherapy treatment techniques for cancer of the cervix are presented, with examples based on the "Stockholm" technique.
Popular Abstract in Uncoded languages Kronična upala je u podlozi mnogih bolesti modernog čovjeka kao što su djiabetes, astma, ateroskleroza itd. Upalu predvode različiti tkivni makrofagi. Proteini iz porodice galektina, proizvedeni u makrofagima, dodatno pridonose razvoju bolesti, stoga je od velikog interesa odgonetnuti različite funkcije galektina. Ovaj rad nastoji identificirati specifične uloContemporary diseases like diabetes, asthma, atherosclerosis etc. are marked by chronic inflammation, often supported by the activity of different macrophages. Proteins from galectin family were found to contribute to disease pathophysiology. Therefore, there is an intensive interest in understanding different galectin functions. The aim of this thesis was to pin-point specific galectin-3 roles in
