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Combined genome and transcriptome sequencing to investigate the plant cell wall degrading enzyme system in the thermophilic fungus Malbranchea cinnamomea

Background: Genome and transcriptome sequencing has greatly facilitated the understanding of biomass-degrading mechanisms in a number of fungal species. The information obtained enables the investigation and discovery of genes encoding proteins involved in plant cell wall degradation, which are crucial for saccharification of lignocellulosic biomass in second-generation biorefinery applications. T

Enhancement of heat transfer in a square channel by roughened surfaces in rib-elements and turbulent flow manipulation

Purpose - The purpose of this paper is to augment heat transfer rates of traditional rib-elements with minimal pressure drop penalties. Design/methodology/approach - The novel geometries in the present research are conventional cylindrical ribs with rounded transitions to the adjacent flat surfaces and with modifications at their bases. All turbulent fluid flow and heat transfer results are presen

Bi-directional Algebraic Graphic Statics : On Force Diagram Constraints

This paper presents a study exploring the capabilities of a new method, described by Åkesson and Alic [1], which extends the capabilities of the algebraic graphic statics method, by Van Mele and Block [11]. The new method extends the algebraic graphic statics method by making it bi-directional i.e. allowing for determination of an updated form diagram by making direct interactive manipulations of

The success of sequence capture in relation to phylogenetic distance from a reference genome : a case study of avian haemosporidian parasites

Genomic sequencing of avian haemosporidian parasites (Haemosporida) has been challenging due to excessive contamination from host DNA. In this study, we developed a cost-effective protocol to obtain parasite sequences from naturally infected birds, based on targeted sequence capture and next generation sequencing. With the genomic data of Haemoproteus tartakovskyi as a reference, we successfully s

Material Selection in Industrial Design Education : A literature review

This study reviews literature on the aspects of material selection within the field of industrial design education, specifically focusing on existing material selection tools and guidelines used in industrial design education. The growing number of materials available today has created a large variety of options for industrial designers, which they are ill-equipped to handle. A key reason behind t

A python framework for solving advection-diffusion problems

This paper discusses a Python interface for the recently published Dune-Fem-DG module which provides highly efficient implementations of the Discontinuous Galerkin (DG) method for solving a wide range of non linear partial differential equations (PDE). Although the C++ interfaces of Dune-Fem-DG are highly flexible and customizable, a solid knowledge of C++ is necessary to make use of this powerful

Ventilation with increased apparatus dead space vs positive end-expiratory pressure : Effects on gas exchange and circulation during anesthesia in a randomized clinical study

Atelectasis formation can be reduced by positive endexpiratory pressure (PEEP), but resulting increases in intrathoracic pressure could affect circulation. We have earlier demonstrated that increased tidal volumes with larger apparatus dead space improves oxygenation and sevoflurane uptake. In the present study, we hypothesize that isocapnic ventilation with increased tidal volumes increases oxyge

Neurofilament light chain on intensive care admission is an independent predictor of mortality in COVID-19 : a prospective multicenter study

BACKGROUND: Neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), and total-tau protein (tau) are novel blood biomarkers of neurological injury, and may be used to predict outcomes in critical COVID-19.METHODS: A prospective multicentre cohort study of 117 consecutive and critically ill COVID-19 patients in six intensive care units (ICUs) in southern Sweden between May and Novem

Safeguarding Food Industry : Understanding Cyberthreats and Ensuring Cybersecurity

The food industry stands as one of the most vital manufacturing sectors globally, with an ever-increasing reliance on digitalization and technology-driven processes. However, this advancement comes with an inherent risk of cyberattacks, encompassing data breaches and system disruptions, which can severely impact production and disrupt the entire food supply chain. Consequently, such cyberthreats c

Gut Micro- and Mycobiota in Preeclampsia : Bacterial Composition Differences Suggest Role in Pathophysiology

Preeclampsia is a severe pregnancy-related inflammatory disease without an effective treatment. The pathophysiology remains partly unknown. However, an increased inflammatory response and oxidative stress are part of the maternal systemic reaction. Recent data have suggested that dysbiosis of the gut microbiome plays a role in preeclampsia as well as other inflammatory diseases. However, dysbiosis

Self-reported quality of life before, during, and after pregnancy in women with CHD

Background:Adults with CHD are a growing patient group and childbirth is a relatively new phenomenon. EQ-5D is commonly used to measure health-related quality of life. We sought to investigate EQ-5D status before, during, and after pregnancy in women with CHD.Methods:We identified 128 pregnancies in 86 CHD women giving birth in Skåne County during 2009–2021. Repeated measures ANOVA was performed t

Analysing vegetation changes in the Sahel using sensor data from Landsat and NOAA

The semi-arid Sahel zone of Africa has suffered several periods of severe drought since about 1950. We have analyzed AVHRR Normalized Difference Vegetation Index (NDVI) over the Sahel for the period 1982-2002, and found extensive areas of increasing NDVI. To verify these changes we have analyzed Landsat TM and ETM+ scenes from 1984-1986 and 1999-2001 for areas in the Sudan, Central African Republi

The eIF2α kinase heme-regulated inhibitor protects the host from infection by regulating intracellular pathogen trafficking

The host employs both cell-autonomous and system-level responses to limit pathogen replication in the initial stages of infection. Previously, we reported that the eukaryotic initiation factor 2α (eIF2α) kinases heme-regulated inhibitor (HRI) and protein kinase R (PKR) control distinct cellular and immune-related activities in response to diverse bacterial pathogens. Specifically for Listeria mono

Resistivity imaging and image analysis for estimating water and solute transport across the capillary fringe in laboratory experiments

This study contains a series of laboratory experiments designed to describe the lateral movement and spatial variability of an infiltrated dye tracer across the capillary fringe of homogenous sand in an aquarium. A combination of image analysis and geoelectrical monitoring was used to track the flow paths of the dye with different hydraulic gradients and infiltration rates. Photographs were taken

Fermentation of Cauliflower and White Beans with Lactobacillus plantarum – Impact on Levels of Riboflavin, Folate, Vitamin B12, and Amino Acid Composition

As diets change in response to ethical, environmental, and health concerns surrounding meat consumption, fermentation has potential to improve the taste and nutritional qualities of plant-based foods. In this study, cauliflower, white beans, and a 50:50 cauliflower-white bean mixture were fermented using different strains of Lactobacillus plantarum. In all treatments containing cauliflower, the pH