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The extreme space weather event in 1903 october/november : An outburst from the quiet sun

While the Sun is generally more eruptive during its maximum and declining phases, observational evidence shows certain cases of powerful solar eruptions during the quiet phase of solar activity. Occurring in the weak Solar Cycle 14 just after its minimum, the extreme space weather event in 1903 October-November is one of these cases. Here, we reconstruct the time series of geomagnetic activity bas

Mocking Others, Parodying Ourselves : Chants and Songs Used in Swedish Football

This article’s aim is to investigate the creative use of parody and sense-/nonsense-making visible in the Swedish football scene by looking into football chants through the lens of parody. The three examples selected (a song, a chant, and a music video) give a glimpse of possible folkloristic investigations in that context, as possibilities to work on varied and extensive material are profound. Th

Bipolar volcanic synchronization of abrupt climate change in Greenland and Antarctic ice cores during the last glacial period

The last glacial period is characterized by a number of millennial climate events that have been identified in both Greenland and Antarctic ice cores and that are abrupt in Greenland climate records. The mechanisms governing this climate variability remain a puzzle that requires a precise synchronization of ice cores from the two hemispheres to be resolved. Previously, Greenland and Antarctic ice

Sensitivity of spatial aerosol particle distributions to the boundary conditions in the PALM model system 6.0

High-resolution modelling is needed to understand urban air quality and pollutant dispersion in detail. Recently, the PALM model system 6.0, which is based on large-eddy simulation (LES), was extended with the detailed Sectional Aerosol module for Large Scale Applications (SALSA) v2.0 to enable studying the complex interactions between the turbulent flow field and aerosol dynamic processes. This s

Lagged atmospheric circulation response in the Black Sea region to Greenland Interstadial 10

Northern Hemispheric high-latitude climate variations during the last glacial are expected to propagate globally in a complex way. Investigating the evolution of these variations requires a precise synchronization of the considered environmental archives. Aligning the globally common production rate variations of the cosmogenic radionuclide 10Be in different archives provides a tool for such synch

Arthroscopic partial meniscectomy for a degenerative meniscus tear : A 5 year follow-up of the placebo-surgery controlled FIDELITY (Finnish Degenerative Meniscus Lesion Study) trial

Objectives: To assess the long-term effects of arthroscopic partial meniscectomy (APM) on the development of radiographic knee osteoarthritis, and on knee symptoms and function, at 5 years follow-up. Design: Multicentre, randomised, participant- A nd outcome assessor-blinded, placebo-surgery controlled trial. Setting: Orthopaedic departments in five public hospitals in Finland. Participants: 146 a

Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges

The contribution of host genetic and nongenetic factors to immunological differences in humans remains largely undefined. Here, we generated bacterial-, fungal-, and viral-induced immune transcriptional profiles in an age- and sex-balanced cohort of 1,000 healthy individuals and searched for the determinants of immune response variation. We found that age and sex affected the transcriptional respo

Spatial distribution and occurrence probability of regional new particle formation events in eastern China

In this work, the spatial extent of new particle formation (NPF) events and the relative probability of observing particles originating from different spatial origins around three rural sites in eastern China were investigated using the NanoMap method, using particle number size distribution (PNSD) data and air mass back trajectories. The length of the datasets used were 7, 1.5, and 3 years at rur

Inverse modelling of European CH4 emissions during 2006–2012 using different inverse models and reassessed atmospheric observations

We present inverse modelling (top down) estimates of European methane (CH4) emissions for 2006–2012 based on a new quality-controlled and harmonised in situ data set from 18 European atmospheric monitoring stations. We applied an ensemble of seven inverse models and performed four inversion experiments, investigating the impact of different sets of stations and the use of a priori information on e

Individualized closed-loop anesthesia through patient model partitioning

Closed-loop controlled drug dosing has the potential of revolutionizing clinical anesthesia. However, interpatient variability in drug sensitivity poses a central challenge to the synthesis of safe controllers. Identifying a full individual pharmacokinetic–pharmacodynamic (PKPD) model for this synthesis is clinically infeasible due to limited excitation of PKPD dynamics and presence of unmodeled d

Born in fire, borne by air : Source attribution and physicochemical characterization of ship and ambient aerosols in the Baltic region

Aerosol emissions from anthropogenic activities cause detrimental health effects and affect the climate system. Combustion is a large source of airborne fine particulate matter (PM2.5) and the uncertainties of the climate role of these emissions are still large. A good understanding of the microphysical properties of aerosols from various sources and their atmospheric aging is essential for accura

Improved survival prognostication of node-positive malignant melanoma patients utilizing shotgun proteomics guided by histopathological characterization and genomic data

Metastatic melanoma is one of the most common deadly cancers, and robust biomarkers are still needed, e.g. to predict survival and treatment efficiency. Here, protein expression analysis of one hundred eleven melanoma lymph node metastases using high resolution mass spectrometry is coupled with in-depth histopathology analysis, clinical data and genomics profiles. This broad view of protein expres

Revisiting the Challenges in Aligning RE and V&V: Experiences from the Public Sector

Successful coordination of Requirements Engineering and Testing (RET) is crucial in large-scale software engineering. If the activities involved in RET are not aligned, effort is inevitably wasted, and the probability of delivering high quality software products in time decreases. Previous work has identified sixteen challenges in aligning RET in a case study of six companies. However, all six cas

Synchronizing the Greenland ice core and radiocarbon timescales over the Holocene-Bayesian wiggle-matching of cosmogenic radionuclide records

Investigations of past climate dynamics rely on accurate and precise chronologies of the employed climate reconstructions. The radiocarbon dating calibration curve (IntCal13) and the Greenland ice core chronology (GICC05) represent two of the most widely used chronological frameworks in paleoclimatology of the past 1/4 g50g000 years. However, comparisons of climate records anchored on these chrono

Real-Time Trajectory Generation Using Model Predictive Control

The problem of planning a trajectory for robots starting in an initial state and reaching a final state in a desired interval of time is tackled. We consider Model Predictive Control as an approach to the problem of point-to-point trajectory generation. We use the developed strategy to generate trajectories for transferring the state of the robot, fulfilling computational real-time requirements. E