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Routine formal fetal movement counting and risk of antepartum late death in normally formed singletons

The routine recommendation to women to count fetal movements daily during late pregnancy for the prevention of antepartum late fetal death in normally formed singletons has been evaluated. 68,000 women were randomly allocated within thirty-three pairs of clusters either to a policy of routine counting or to standard care, which might involve selective use of formal counting or informal noting of m

Limited diversity of the protein D gene (hpd) among encapsulated and nonencapsulated Haemophilus influenzae strains

Protein D is a surface-exposed lipoprotein of the gram-negative bacterium Haemophilus influenzae with affinity for human immunoglobulin D myeloma protein. The gene encoding protein D (hpd) in a serotype b strain of H. influenzae was cloned. Escherichia coli carrying the hpd gene bound human myeloma immunoglobulin D. Nucleotide sequence analysis identified an 1,092-bp open reading frame that was mo

Functional consequences of insertions and deletions in the complementarity-determining regions of human antibodies

Insertions and deletions of nucleotides in the genes encoding the variable domains of antibodies are natural components of the hypermutation process, which may expand the available repertoire of hypervariable loop lengths and conformations. Although insertion of amino acids has also been utilized in antibody engineering, little is known about the functional consequences of such modifications. To i

In vivo compartmentalization of functionally distinct, rapidly responsive antigen-specific T-cell populations in DNA-immunized or Salmonella enterica serovar Typhimurium-infected mice

The location and functional properties of antigen-specific memory T-cell populations in lymphoid and nonlymphoid compartments following DNA immunization or infection with Salmonella were investigated. Epitope-specific CD8+-T-cell expansion and retention during the memory phase were analyzed for DNA-immunized mice by use of a 5-h peptide restimulation assay. These data revealed that epitope-specifi

Antibody-based microarrays.

Antibody-based microarrays are a new powerful proteomic technology that can be used to generate rapid and detailed expression profiles of defined sets of protein analytes in complex samples as well as high-resolution portraits of entire proteomes. Miniaturized micro- and nanoarrays can be printed with numerous antibodies carrying the desired specificities. Multiplexed and ultra-sensitive assays, s

Fluorescent leukotriene B-4: potential applications

Leukotriene B-4 (LTB4) is a potent lipid mediator of inflammation that acts primarily via a seven-transmembrane-spanning, G-protein-coupled receptor denoted BLT1. Here, we describe the synthesis and characterization of fluorescent analogs of LTB4 that are easy to produce, inexpensive, and without the disadvantages of a radioligand. Fluorescent LTB4 is useful for labeling LTB4 receptors for which n

Age and reproduction in lesser spotted woodpeckers (Dendrocopos minor)

We examined the influence of female age, male age, and pair-bond duration on start of egg-laying, clutch size, and number of young fledged in the Lesser Spotted Woodpecker (Dendrocopos minor). We also attempted to disentangle the relative influence of individual age and pair-bond duration on reproduction, because the effect of those factors may be confounded. Brooding performance improved with age

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Detta är ett kapitel i en volym vars syfte är att studera det fantastiska i litteratur från olika delar av den fransktalande världen. Mitt bidrag handlar om fallet Patrick Chamoiseau som ett exempel på modern användning av det fantastiska i västindisk litteratur.This is a chapter in a volume whose aim is to study the fantastic in literature from different parts of the French speaking world. My contribution deals with the case of Patrick Chamoiseau as an example of the modern use of the fantastic in Carribean literature.

Diagnosis of tuberculous meningitis: a comparative analysis of 3 immunoassays, an immune complex assay and the polymerase chain reaction

OBJECTIVE: To compare 3 immunoassays, an immune complex assay, and an application of the polymerase chain reaction (PCR) for the diagnosis of tuberculous meningitis (TBM). MATERIAL: Cerebrospinal fluid (CSF) from 33 patients with TBM and from 34 control patients with infectious and non-infectious CNS diseases was analysed. RESULTS: The antibody immunoassays were either nonspecific or insensitive.

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Pragmadialektiikan maailmanvalloitus alkoi kaksikymmentäviisi vuotta sitten. Tänään se on yhtä tunnettu kuin jo viisikymmentä vuotta täyttäneet Toulminin ja Perelmanin uraauurtavat argumentaation teoriat. Arviot pragmadialektiikasta kuitenkin vaihtelevat huomattavan paljon. J. Anthony Blair on esimerkiksi luonnehtinut sitä maailman tärkeimmäksi argumentaation teoriaksi tänä päivänä. John Woodsin m

Transported Immobility

In this chapter I take Barthes’ concept of transported immobility and allow it to travel from the dining car of a French train to the forests of Sweden and to my own experience of living in a digital media blackout zone. In ‘Dining Car’, Barthes’ reflects on the contrary experience of eating an elaborate meal in an upscale restaurant carriage. This entire mise-en-scene Barthes’ describes as a ‘mir