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Accuracy of MRI in early rectal cancer: national cohort study

Radiological staging of rectal cancer dictates subsequent patienttreatment. In early-stage disease, local excision is associatedwith reduced morbidity, mortality, and costs, and maintainsbowel continuity compared with surgery, where the whole orpart of the rectum is resected1–3. Nearly 90 per cent of patientswith T1 rectal cancer have N0 disease and are therefore potentially curable with local res

Estimation of required beach nourishment volumes along the south coast of Sweden during 2017–2100

Flera platser utmed den skånska kusten har idag problem med stranderosion som innebär att havet äter sig inåt land så att stränder och kustlandskap försvinner. När havet stiger förväntas stranderosionen att öka och även kust sträckor som idag inte har problem kan komma att drabbas. Då kustlinjen rör sig inåt land hotas bebyggelse, infra struktur och naturområden, samtidigt som översvämningsrisken Beach erosion is expected to increase as the sea level rises during the coming decades. A retreating coastline threat ens infrastructure, settlements, nature habitats, and at the same time increases the flood risk in low-lying areas. On the Swedish south coast, beach erosion is a problem at present likely to increase due to the sea level rise. For main taining the beaches and protecting the hinter

Dispatchable Battery Swapping System with Centralized Charging and Renewable Energy Generation

The effort to electrify society has in recent years resulted in major changes in the transportation sector. Charging time remains a challenge in several applications such as transportation and heavy machinery. A proposed solution that shortens the energy replenishment time and adds flexibility in loading the grid is to battery-swapping: exchanging the depleted battery for a fully charged one. In s

1-Hour Post-OGTT Glucose Improves the Early Prediction of Type 2 Diabetes by Clinical and Metabolic Markers

CONTEXT: Early prediction of dysglycemia is crucial to prevent progression to type 2 diabetes. The 1-hour postload plasma glucose (PG) is reported to be a better predictor of dysglycemia than fasting plasma glucose (FPG), 2-hour PG, or glycated hemoglobin (HbA1c). OBJECTIVE: To evaluate the predictive performance of clinical markers, metabolites, HbA1c, and PG and serum insulin (INS) levels during

Crime, disorder, and territorial stigmatization : Older adults living in deprived neighborhoods

BACKGROUND AND OBJECTIVES: The existence of social problems, crime, and a diminishing sense of community are acknowledged challenges to residents of deprived neighborhoods. In research on deprived neighborhoods in Sweden, the perspectives of young residents and adults of working age dominate. This study explores how older adults in deprived neighborhoods in Sweden experience crime and disorder, an

Temperature-Dependent Exciton Dynamics in J-Aggregates-When Disorder Plays a Role.

Absorption and fluorescence spectral properties of J-aggregates of core-tetrasubstituted perylene bisimide (PBI) dyes have been investigated in the temperature range from 300 to 5 K. A special feature of the present PBI J-aggregates is that, in contrast to classical J-aggregates like that of pseudoisocyanine (PIC), the chromophores are held together not only by van-der-Waals interactions but also

l2 gain bounded adaptive control of a first order linear system

The problem of adaptive control is considered from a perspective of l2-gain. It has recently been shown that without an a priori bound on the system parameters, there exists no single dynamic feedback law that achieves bounded gain from disturbances to state for all first order linear systems. In this paper, a converse statement is proved for a standard adaptive scheme where the parameter estimate

Time Scales of Conformational Gating in a Lipid-Binding Protein

Lipid-binding proteins Sequester amphiphilic molecules in a large internal : cavity occupied by similar to 30 water molecules, some of which are displaced by the ligand. The role; of these internal water molecules in lipid binding and release is not understood. We use magnetic relaxation dispersion (MRD) to directly monitor internal-water dynamics in apo and palmitate-bound rat intestinal fatty ac