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Background: We aimed to assess the risk of serious infections in patients with inflammatory bowel disease (IBD) exposed to different advanced therapies. Methods: We linked nationwide registers and compared rates of incident serious infections in patients with Crohn’s disease (CD) and ulcerative colitis (UC) exposed to medical therapies versus matched general population comparators during 2007-2023

Introduction: Using time-limited trials of low-dose, sustained-release morphine to reduce chronic breathlessness to evaluate net effects may generate opioid withdrawal symptoms if medication is ceased. This sub-study of a larger randomized, placebo-controlled, double-blind trial aimed to evaluate if this occurred. Methods: People with modified Medical Research Council breathlessness scores of 3 or

Accurate, high-resolution global land use and land cover (LULC) mapping is crucial for environmental monitoring, but remains challenging when relying solely on multispectral data. Most existing global LULC mapping studies rely exclusively on multispectral observations, and even those that incorporate synthetic aperture radar (SAR) data often fail to fully exploit the information it provides. SAR p

BackgroundThe Job Demand–Control–Support (JD-C-S) model evaluates how psychosocial work factors affect health and performance. We examined how demographics, job title, and experience influence demand, control, and support among Ghanaian pharmacy staff.MethodsA cross-sectional survey of pharmacy personnel from Tamale and Sagnerigu was conducted using the JD-C-S questionnaire. Demand and control ite

Introduction Systemic inflammation is postulated to mediate heat stroke and heat-related organ injury, yet acute inflammatory responses among heat-stressed workers remains poorly understood. We aimed to describe neutrophil mobilisation and potential release of DNA during heat stress in multiple hot occupational settings and a controlled experimental setting. Methods Neutrophil:lymphocyte ratio (NL

Objectives: Panax ginseng (P. ginseng, C.A. Meyer) is suggested to improve blood glucose regulation, but evidence remains inconsistent. We examined whether consuming P. ginseng as a preload before a carbohydrate-rich meal modulates postprandial glucose and insulin responses. Methods: In a randomized, double-blind, crossover trial, 22 healthy middle-aged adults consumed P. ginseng tablets containin

BACKGROUND AND OBJECTIVE: Achieving adequate concentrations of beta-lactam antibiotics in patients with severe infections is challenging, and therefore therapeutic drug monitoring (TDM) would be optimal for guiding beta-lactam dosing, but is often limited by availability. UV/VIS spectrophotometry can quantify drug levels in saline, and if those levels truly reflect plasma concentrations, it could

We present a comparative analysis of the unfolding and inactivation of three cutinases in the presence of guanidine hydrochloride (GdnHCl) and bis(2-ethylhexyl) sodium sulfasuccinate (AOT). Previous investigations have focused on the cutinase from Fusarium solani pisi (FsC). In addition to FsC, the present study includes the cutinase from Humicola insolens (HiC) and a mutant variant of HiC (mu HiC

Science Weeks tackled the great challenges of our time / page 8 Jubilee Course with a wow-factor / page 16 Some jubilee highlights / page 18 Lund University’s 350th anniversary – A LOOK BACK AT THE 13-MONTH YEAR 1 Lund University’s 350th anniversary celebrations ran between 19 Decem- ber 2016 and 28 January 2018, shin- ing a spotlight on the University’s education, research, innovations, external

https://www.lu.se/sites/www.lu.se/files/lund-university-350th-anniversary.pdf - 2026-05-08

LUMES: Lund University Master’s Programme in Environmental Science The contribution of the Mexican environmental policies to the efficient solution of the problem of air pollution” By Ana Luz Romero Salcedo January, 2005 Submitted in partial fulfilment of the requirements of the International Master in Environmental Sciences degree, Lund University, Sweden Submitted by: Ana Luz Romero Salcedo Av.

https://www.lumes.lu.se/sites/lumes.lu.se/files/romero_ana.pdf - 2026-05-08

COSM25 course outline 2025 COSM25 Contemporary South-East Asian Societies Spring semester 2025 Course director: Astrid Norén-Nilsson (astrid.noren_nilsson@ace.lu.se) Other teachers and guest lecturers: Chontida Auikool, Kimhean Hok, Hyejin Kim, Macario Lacbawan, Tabita Rosendal Ebbesen, Helle Rydström, Emilie Wellfelt Office hours: By appointment Course description The course deals with social, cu

https://www.ace.lu.se/sites/ace.lu.se/files/2024-12/COSM25%20course%20outline%202025.pdf - 2026-05-08

Publikationer av SAPES PIs 2010-2012 Andersson, G. K. S., Rundlöf, M., and Smith, H. G. 2012 Organic Farming Improves Pollination Success in Strawberries. Plos One 7. Andersson, G. K. S., Rundlöf, M., and Smith, H. G. 2010 Time lags in biodiversity response to farming practices. Aspects of Applied Biology 100, 381-384. Bejai, S., Fridborg, I., and Ekbom, B. 2012 Varied response of Spodoptera litto

https://www.cec.lu.se/sites/cec.lu.se/files/sapes_pi_publication_list.pdf - 2026-05-08

Seroconversion to Multiple Islet Autoantibodies and Risk of Progression to Diabetes in Children Seroconversion to Multiple Islet Autoantibodies and Risk of Progression to Diabetes in Children Anette G. Ziegler, MD, Marian Rewers, MD, PhD, Olli Simell, MD, PhD, Tuula Simell, MPH, PhD, Johanna Lempainen, MD, PhD, Andrea Steck, MD, Christiane Winkler, PhD, Jorma Ilonen, MD, PhD, Riitta Veijola, MD, P

https://www.gppad.lu.se/sites/gppad.lu.se/files/2025-05/Seroconversion_to_multiple_.pdf - 2026-05-08

HIV infection affects the course of tuberculosis (TB), and HIV and Mycobacterium tuberculosis (Mtb) synergize in disease progression through complex immunological interplay. To gain further understanding of these mechanisms, we compared the microRNA (miRNA) and small nucleolar RNA (snoRNA) expression patterns in whole blood of individuals with active TB, with and without HIV coinfection (HIV+/TB+

Objectives: Type I interferons (IFNs) are central and reflective of disease activity in systemic lupus erythematosus (SLE). However, IFN-α levels are notoriously difficult to measure and the type I IFN gene signature (IGS) is not yet available in clinical routine. This study evaluates galectin-9 and an array of chemokines/cytokines in their potential as surrogate markers of type I IFN and/or SLE d

OBJECTIVE: This analysis aimed to compare failure to rescue (FTR) after pancreatoduodenectomy across the Atlantic. SUMMARY BACKGROUND DATA: FTR, or mortality after development of a major complication, is a quality metric originally created to compare hospital results. FTR has been studied in North American and Northern European patients undergoing pancreatoduodenectomy (PD). However, a direct comp

BACKGROUND: ECG abnormalities are associated with adverse outcomes in the general population, but their prognostic significance in severe mental illness (SMI) remains unexplored. We investigated associations between no, minor, and major ECG abnormalities and fatal cardiovascular disease (CVD) among patients with SMI compared with controls without mental illness. METHODS AND RESULTS: We cross-linke

CONTEXT: Turner syndrome (TS) is the most common chromosomal aberration in women; it is the result of structural or numeric abnormalities in the X chromosome. Autoimmune hypothyroidism has been recognized as one of the more prominent disorders associated with TS. OBJECTIVE: This work aimed to study the prevalence of autoimmune diseases in TS. METHODS: A cross-sectional, longitudinal, 25-year follo

BACKGROUND: It is well-known that infectious complications after central venous catheterisation are associated with increased mortality, length of hospital stay and costs. However, there are limited data regarding such associations for immediate insertion-related complications. Therefore, the aim of this study was to investigate whether major immediate insertion-related complications are associate

Heart failure (HF) and cancer are common diseases among the elderly population. Many chronic diseases, including diabetes mellitus (DM), share risk factors and increase the incidence of HF and cancer. The aim of this study was to investigate if there was an association between HF and the prevalence of haematologic- and solid malignancies. Methods The study population was comprised of almost one mi