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Brain Plasticity 3 (2017/2018) 195–203 DOI 10.3233/BPL-180066 IOS Press 195 Review Crosstalk between MicroRNAs and Autophagy in Adult Neurogenesis: Implications for Neurodegenerative Disorders Karolina Pircs1, Rebecca Petri1 and Johan Jakobsson∗ Department of Experimental Medical Science, Laboratory of Molecular Neurogenetics, Wallenberg Neuroscience Center and Lund Stem Cell Center, Lund Universi
Land use change and health: A case study of fish farming impacts on malaria prevalence in Kabale district, Uganda. Thesis submitted in partial fulfilment of the requirements for the Master of Science degree in Environmental Studies and Sustainability Science (LUMES) By Kiirya David dlavinco@yahoo.com Supervisor: Dr. Nicodemus Mandere, PhD Lund University Centre for Sustainability Studies (LUCSUS)
https://www.lumes.lu.se/sites/lumes.lu.se/files/kiirya_david_thesis_2011.pdf - 2026-05-16
Objective High vitreous levels of soluble (s)CD163 have been demonstrated in severe diabetic retinopathy (DR). The aim of this study was to explore the predictive values of plasma sCD163 and glycated haemoglobin (HbA1c) for DR progression in adults with type 1 diabetes. Methods and analyses The study design was prospective. Fundus photography performed in 2009 and at follow-up (≤12 years later) we
Aquatic organisms are constantly at risk of being exposed to potentially harmful chemical compounds of natural or anthropogenic origin. Biological life can for instance respond to chemical stressors by changes in gene expression, and thus, certain gene transcripts can potentially function as biomarkers, i.e. early warnings, of toxicity and chemical stress. A major challenge for biomarker applicati
A novel metabolomic method based on gas chromatography-mass spectrometry was applied to investigate serum metabolites in response to dietary Gln supplementation in piglets. Sixteen, 21-d-old pigs were weaned and assigned randomly to 2 isonitrogenous diets: 1) Gln diet, which contained 1% L-Gln (as-fed basis), and 2) control diet, which contained LAla to make this diet isonitrogenous with the Gln d
Purpose: To analyse risk of vision impairment (VI) and blindness in adult foreign-born individuals and Swedish-born individuals. Methods: A nationwide study of individuals 18 years of age and older (N = 6,042,891; 2,902,918 men and 3,139,973 women) in Sweden. VI (in general) and blindness was defined as at least one registered diagnosis in the National Patient Register between January 1, 1998 and
Mutations in either mitochondrial DNA (mtDNA) or nuclear genes that encode mitochondrial proteins may lead to dysfunctional mitochondria, giving rise to mitochondrial diseases. Some mitochondrial myopathies, however, present without a known underlying cause. Interestingly, methylation of mtDNA has been associated with various clinical pathologies. The present study set out to assess whether mtDNA
Methanol (CH3OH) is an attractive alternative fuel that can reduce net carbon release and decrease pollutant emissions. In this study, methanol and n-dodecane spray flames were investigated using Large-Eddy Simulation (LES) and direct coupling with finite-rate chemistry. The selected ambient conditions are relevant to engines and were previously unreported for numerical methanol spray studies, i.e
The Arctic is undergoing a shift toward a warmer and wetter climate. Recent experiments indicate that the carbon balance of subarctic wet tundra is sensitive to both summer warming and deeper snow. However, few studies have combined experimental data with process-oriented models to predict how the terrestrial carbon cycle will respond to future climate change. Here, we use CoupModel, a process-ori
Introduction: Airway management is a critical component of out-of-hospital cardiac arrest (OHCA) resuscitation. The primary aim of this study was to describe pre-hospital airway management in adult patients post-OHCA. Secondary aims were to investigate whether tracheal intubation (TI) versus use of supraglottic airway device (SGA) was associated with patients’ outcomes, including ventilator-free d
Background: Premature ventricular complexes (PVCs) predict coronary heart disease, heart failure, atrial fibrillation and death, all of which are also related to sodium intake. We studied estimated sodium intake and PVC frequency in the randomly selected population-based Swedish CArdioPulmonary bioImage Study cohort. Methods: In our cross-sectional study, we included 5636 individuals with 24-hour
Genom Bohuslän, mellan Strömstad och Göteborg, löper en järnväg. En järnväg som heter Bohusbanan. En järnväg som en gång i tiden var en symbol för framtidstro och utveckling. Banans praktfulla stationshus, de första som välkomnar en och den sista som vinkar adjö vid ett besök till en av de många orterna längs järnvägen, står idag som barriärer till samhällena de tillhör. Byggnaderna som en gång vaThrough Bohuslän, between Strömstad and Gothenburg, runs a railway. A railway called Bohusbanan. A railway that was once a symbol of optimism and progress. The line’s grand station buildings—the first to welcome and the last to bid farewell to visitors of the many towns along the route—now stand as barriers to the communities they belong to. Buildings that were once open, public, social spaces own
Objectives. To prospectively evaluate the incidence of transitional cell carcinoma (TCC) in the prostatic urethra and prostate in the cystoprostatectomy specimen, investigate characteristics of bladder tumours in relation to the risk of involvement of the prostatic urethra and prostate and examine the sensitivity of preoperative loop biopsies from the prostatic urethra. Material and methods. Preop
OBJECTIVE: To analyse the association between use of antihypertensive treatment, diastolic blood pressure, and long term incidence of ischaemic cardiac events in elderly men. DESIGN: Population based cohort study. Baseline examination in 1982-3 and follow up for up to 10 years. SETTING: Malmo, Sweden. SUBJECTS: 484 randomly selected men born in 1914 and living in Malmo during 1982. MAIN OUTCOME ME
Seventy-three Swedish blood donors (52 men, 21 women; median age 36 years) repeatedly reactive for hepatitis C antibodies (anti-HCV C-100-3) were tested with a second-generation (2nd-gen) anti-HCV Elisa and a 4-band recombinant immunoblot assay (RIBA 2). These results were correlated to serum alanine aminotransferase (S-ALAT), liver morphology and viremia as detected by 'nested' polymerase chain r
OBJECTIVE: The potential association between thyroid hormones and breast cancer has been investigated in a large number of studies without conclusive results. This study investigated T3 levels in relation to breast cancer mortality in a population with no breast cancer patients at baseline. An additional aim was to study T3 levels in relation to mortality from other cancers and all-cause mortality
Objective: To assess perioperative outcomes of percutaneous nephrolithotomy (PCNL) using ultrasound or fluoroscopic guidance for percutaneous access. Methods: A prospectively collected international Clinical Research Office of the Endourological Society (CROES) database containing 5806 patients treated with PCNL was used for the study. Patients were divided into two groups based on the methods of
Objectives. To explore whether a reduced lung function is a risk factor for developing diabetes and insulin resistance (IR), and whether such relationship contributes to the largely unexplained association between lung function and incidence of cardiovascular disease (CVD). Design. Forced vital capacity (FVC) was assessed at baseline. Incidence of diabetes and IR [according to the homeostasis mod
