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Thyroid function has a widespread effect on the cardiometabolic system. However, the causal association between either subclinical hyper-or hypothyroidism and the thyroid hormones with blood pressure (BP) and cardiovascular diseases (CVD) is not clear. We aim to investigate this in a two-sample Mendelian randomization (MR) study. Single nucleotide polymorphisms (SNPs) associated with thyroid-stimu

The recent advent of Optical Photothermal IR (O-PTIR), has enabled for the first time, submicron infrared microscopy in far-field reflection mode with the combination of Raman for simultaneous, correlative IR+Raman microscopy. These unique and exciting synergistic capabilities are now spawning interest in life science application. A broad range of life science applications, otherwise impossible wi

Pure hydrocarbons with shape and conjugation properties that can be switched by external stimuli is an intriguing prospect in the design of new responsive materials and single-molecule electronics. Here, we develop an oligomeric [8]annulene-based material that combines a remarkably efficient topological switching upon redox changes with structural simplicity, stability, and straightforward synthes

In this study, we demonstrate an acoustofluidic device that enables single-file focusing of submicron particles and bacteria using a two-dimensional (2D) acoustic standing wave. The device consists of a 100 μm × 100 μm square channel that supports 2D particle focusing in the channel center at an actuation frequency of 7.39 MHz. This higher actuation frequency compared with conventional bulk acoust

Neurotensin (NT) is a small peptide with pleiotropic functions, exerting its primary actions by controlling food intake and energy balance. The first evidence of an involvement of NT in metabolism came from studies on the central nervous system and brain circuits, where NT acts as a neurotransmitter, producing different effects in relation to the specific region involved. Moreover, newer interesti

Background: Arterial stiffness is independently associated with orthostatic hypotension. We aimed to investigate the relationship between orthostatic blood pressure reaction and arterial stiffness as well as central hemodynamics in younger subjects from the general population.Methods: We analyzed a large prospective cohort study of 3756 individuals from the general population (mean age 41.9±14.5 y

We report on local nowcasting (short-term forecasting) of coronavirus disease (COVID-19) hospitalizations based on syndromic (symptom) data recorded in regular healthcare routines in Östergötland County (population ≈465,000), Sweden, early in the pandemic, when broad laboratory testing was unavailable. Daily nowcasts were supplied to the local healthcare management based on analyses of the time la

Background/aim: Residual disease (RD) after primary debulking surgery (PDS) is a prognostic factor for survival in advanced ovarian cancer (AOC). This study aimed to examine whether the tumor extent affects overall survival (OS) and progression-free survival (PFS) in AOC patients treated with PDS.Patients and methods: A total of 118 patients treated with PDS were included. Age, ECOG score, AOC Int

PurposeEpithelial ovarian cancer is usually diagnosed in the advanced stages. To choose the best therapeutic approach, an accurate preoperative assessment of the tumour extent is crucial. This study aimed to determine whether the peritoneal cancer index (PCI), the amount of ascites, and the presence of cardiophrenic nodes (CPLNs) visualized by computed tomography (CT) can assess the tumour extent

Type 2 diabetes (T2D) and cardiovascular disease (CVD) represent significant disease burdens for most societies and susceptibility to these diseases is strongly influenced by diet and lifestyle. Physiological changes associated with T2D or CVD, such has high blood pressure and cholesterol and glucose levels in the blood, are often apparent prior to disease incidence. Here we integrated genetics, l

Förbudet mot köp av sexuella tjänster har varit i kraft i 16 år. Den debatt som åtföljt lagstiftningsarbetet kan dock sägas ha pågått under närmare 40 år. Det är en debatt med starka ideologiska förtecken och det är tydligt att prostitution är en fråga som inte lämnar någon oberörd. Uppsatsens syfte är utreda vilka ideologiska värderingar och skyddsintressen som återfinns i lagstiftarens syn på pThe Swedish prohibition of the purchase of a sexual service has been in effect for 16 years. The debate accompanying the legislation process has, however, been going on for almost 40 years. It is a debate with a strong ideological nature and it is clear that prostitution is a phenomenon that leaves no one unaffected. The aim of this essay is to investigate which ideological values have affected th

Enligt svensk rätt ska utländska äktenskap erkännas om de är giltiga enligt lagen i det land de ingåtts. Undantaget till detta är om äktenskapet går emot svensk ordre public. Huruvida så är fallet för polygami är fortfarande osäkert. Det här arbetet kommer inte beröra huruvida Sverige bör ha en begränsning på antal äktenskap eller inte, utan fokus ligger på den svenska hanteringen av utländska polAccording to Swedish law a foreign marriage is recognized if it is valid under the law of the state where it was entered into. The exception to this is if such a marriage is void as a matter of public policy. Whether or not that applies to polygamy is still uncertain. This thesis will not touch upon whether or not Sweden should have a restriction on the number of parties in a marriage; instead it

Att ha förtalat någon är att ha begått ett brott. Men processrätten kring förtalsbrottet skiljer sig från vanliga brott. Om brottet varit tillräckligt kvalificerat tar åklagare över åtalet som ett allmänt åtal men om det inte nått upp till denna gräns har det ålegat den enskilde att väcka åtal. Det är främst den typen av brott som inte nått upp till gränsen för allmänt åtal som denna uppsats tagitTo have slandered someone is to have committed a crime. But the procedure surrounding the crime of slander differs from regular crimes. If the crime is considered qualifying enough a prosecutor will take over the case as general prosecution but if the crime hasn’t lived up to that level it’s up to the individual to arouse individual prosecution. It’s mainly the type of offense that doesn’t qualify

Mantle plumes are subject of a great discussion within the field of Geology. Do they really exist, and in that case, from where do they originate? The scope of this Bachelor thesis is to discuss the characteristics of mantle plumes and the arguments in favor of and against their proposed existence. The mantle plume hypothesis was first presented in 1971 by Jason Morgan, suggesting diapirs of hot r

Plasma ascorbic acid and the risk of islet autoimmunity and type 1 diabetes: the TEDDY study ARTICLE Plasma ascorbic acid and the risk of islet autoimmunity and type 1 diabetes: the TEDDY study Markus Mattila1,2 & Iris Erlund2,3 & Hye-Seung Lee4 & Sari Niinistö2 & Ulla Uusitalo4 & Carin Andrén Aronsson5 & Sandra Hummel6,7,8 & Hemang Parikh4 & Stephen S. Rich9 & William Hagopian10 & Jorma Toppari11

https://www.teddy.lu.se/sites/teddy.lu.se/files/plasma_ascorbic_acid_and_the_risk_of_islet_autoimmunity_and_type_1_diabetes._pdf.pdf - 2026-05-06

Bakgrund: Pes Equino Varus Adductus (PEVA), även känt som klumpfot, är en medfödd felställning i fotens leder som kräver omfattande behandling under flera år. Det finns ett fåtal studier om hur PEVA påverkar barns grovmotoriska utveckling. Mer kunskap behövs om vilka faktorer som eventuellt kan påverka den grovmotoriska utvecklingen. Syfte: Att beskriva och jämföra utveckling av grovmotorik och pa