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Increased registration of hypertension and cancer diagnoses after the introduction of a new reimbursement system

Objective. To investigate the impact on ICD coding behaviour of a new case-mix reimbursement system based on coded patient diagnoses. The main hypothesis was that after the introduction of the new system the coding of chronic diseases like hypertension and cancer would increase and the variance in propensity for coding would decrease on both physician and health care centre (HCC) levels. Design. C

3D Spectroscopy of Vibrational Coherences in Quantum Dots: Theory.

In semiconductor nanocrystals, called quantum dots (QD), electronic transition energies, phonon frequencies, and electron-phonon coupling strengths are all reported to depend on the size of the crystals. The size dependencies of the transition energies and the mode frequencies are well characterized and understood. At the same time, the electron-phonon coupling dependence on size is controversial-

Porosity and Surface Properites of SBA-15 with Grafted PNIPAAM: A Water Sorption Calorimetry Study

Mesoporous silica SBA-15 was modified in a three-step process to obtain a material with poly-N-isopropylacrylamide (PNIPAAM) grafted onto the inner pore surface. Water sorption calorimetry was implemented to characterize the materials obtained after each step regarding the porosity and surface properties. The modification process was carried out by (i) increasing the number of surface silanol grou

Nonlinear response of quantum cascade structures

The gain spectrum of a terahertz quantum cascade laser is analyzed by a nonequilibrium Green's functions approach. Higher harmonics of the response function were retrievable, providing a way to approach nonlinear phenomena in quantum cascade lasers theoretically. Gain is simulated under operation conditions and results are presented both for linear response and strong laser fields. An iterative wa

Prediction of progression of radiographic knee osteoarthritis using tibial trabecular bone texture

Objective To develop a system for predicting the progression of radiographic knee osteoarthritis (OA) using tibial trabecular bone texture. Methods. We studied 203 knees with (n = 68) or without (n = 135) radiographic tibiofemoral OA in 105 subjects (90 men and 15 women with a mean age of 54 years) in whom 2 sets of knee radiographs were obtained 4 years apart. We determined medial and lateral com

Capture the Fracture: a Best Practice Framework and global campaign to break the fragility fracture cycle.

The International Osteoporosis Foundation (IOF) Capture the Fracture Campaign aims to support implementation of Fracture Liaison Services (FLS) throughout the world. INTRODUCTION: FLS have been shown to close the ubiquitous secondary fracture prevention care gap, ensuring that fragility fracture sufferers receive appropriate assessment and intervention to reduce future fracture risk. METHODS: Capt

A phonon scattering assisted injection and extraction based terahertz quantum cascade laser

A lasing scheme for terahertz quantum cascade lasers, based on consecutive phonon-photon-phonon emissions per module, is proposed and experimentally demonstrated. The charge transport of the proposed structure is modeled using a rate equation formalism. An optimization code based on a genetic algorithm was developed to find a four-well design in the GaAs/Al0.25Ga0.75As material system that maximiz

Nanoparticle-based pseudostationary phases in CEC: A breakthrough in protein analysis?

This review focuses on major trends in nanoparticle-based pseudostationary phase (PSP) CEC since the publication of our previous reviews within nanoparticle-based CEC [Nilsson, C., et al., Electrophoresis 2006, 27, 76-83; Nilsson, C., et al., J. Chromatogr. A 2007, 1168, 212-224.]. Special attention is given to the development toward protein analysis, which is driven by the strong emergence of pro

Storage and Recall of Weak Coherent Optical Pulses with an Efficiency of 25%

We demonstrate experimentally an efficient coherent rephasing scheme for the storage and recall of weak coherent light pulses in an inhomogeneously broadened optical transition in a Pr3+: YSO crystal at 2.1 K. Precise optical pumping using a frequency stable (approximate to 1 kHz linewidth) laser is employed to create a highly controllable atomic frequency comb structure. We report single photon l

Invited Commentary: Multilevel Analysis of Individual Heterogeneity-A Fundamental Critique of the Current Probabilistic Risk Factor Epidemiology

In this issue of the Journal, Dundas et al. (Am J Epidemiol. 2014;180(2):197-207) apply a hitherto infrequent multilevel analytical approach: multiple membership multiple classification (MMMC) models. Specifically, by adopting a life-course approach, they use a multilevel regression with individuals cross-classified in different contexts (i.e., families, early schools, and neighborhoods) to invest

In Vitro Neo-Cartilage Formation on a Three-Dimensional Composite Polymeric Cryogel Matrix

Limited blood supply and the avascular nature of articular cartilage restricts its self repair capacity, frequently leading to osteoarthritis. This work focuses on scaffolds for tissue repair from natural polymers, for example gelatin, chitosan, and agarose in the form of composite. A novel way of fabrication, known as cryogelation, is presented, in which matrices are synthesized at sub-zero tempe

Variation in the PTH2R gene is associated with age-related degenerative changes in the lumbar spine.

In the elderly, degenerative changes in the lumbar spine are common, contributing to falsely elevated bone mineral density (BMD) values. The parathyroid hormone (PTH) system plays an important role in the regulation of bone turnover and we explore the hypothesis that polymorphisms (SNPs) within genes in this pathway (PTH, PTHLH, PTH1R and PTH2R) contribute to degenerative manifestations of the spi

Prevalence of Doctor-Diagnosed Thumb Carpometacarpal Joint Osteoarthritis: An Analysis of Swedish Health Care

Objective. While the prevalence of radiographic thumb carpometacarpal (CMC1) osteoarthritis (OA) is well-described, little is known about clinically symptomatic disease presenting to physicians for care. We sought to determine the prevalence of doctor-diagnosed CMC1 OA. Methods. Using health care data from Skane in southern Sweden (population 1.24 million), we identified all adults ages >= 20 year

The association between radiographic severity and pre-operative function in patients undergoing primary knee replacement for osteoarthritis

Objective: To determine the association between radiographic osteoarthritis (OA) and pre-operative function in patients undergoing primary knee replacement. Methods: Single centre study examining pre-operative outcomes in a consecutive series of 525 patients who underwent primary knee replacement for OA between January 2006 and December 2007. Pre-operative data included: demographics, American Soc

Worker Productivity Outcome Measures: OMERACT Filter Evidence and Agenda for Future Research

The objective of the Outcome Measures in Rheumatology (OMERACT) Worker Productivity working group is to identify worker productivity outcome measures that meet the requirements of the OMERACT filter. At the OMERACT I I Workshop, we focused on the at-work limitations/productivity component of worker productivity (i.e., presenteeism) an area with diverse conceptualization and instrumentation approac

Genetic Determinants of Serum Testosterone Concentrations in Men

Testosterone concentrations in men are associated with cardiovascular morbidity, osteoporosis, and mortality and are affected by age, smoking, and obesity. Because of serum testosterone's high heritability, we performed a meta-analysis of genome-wide association data in 8,938 men from seven cohorts and followed up the genome-wide significant findings in one in silico (n = 871) and two de novo repl