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Positive patch test reactions to oxidized limonene: exposure and relevance

Background. R-Limonene is a common fragrance terpene found in domestic and industrial products. R-Limonene autoxidizes on air exposure, and the oxidation products can cause contact allergy. In a recent multicentre study, 5.2% (range 2.3-12.1%) of 2900 patients showed a positive patch test reaction to oxidized R-limonene. Objective. To study the exposure to limonene among consecutive dermatitis pat

Generalised and Particularistic Thinking in Policy Analysis and Practice: The Case of Governance Reform in South Africa

This article is concerned with the relationship between generalised and particularistic knowledge in the context of policy-making and policy analysis. It argues that it is problematic to assume that a reform model will generate similar outcomes across a wide variety of contexts. It presents a conceptual framework, including the concepts of transaction domain and domain consensus, that enables cont

Statistical Modeling and Estimation of Censored Pathloss Data

Pathloss is typically modeled using a log-distance power law with a large-scale fading term that is log-normal. However, the received signal is affected by the dynamic range and noise floor of the measurement system used to sound the channel, which can cause measurement samples to be truncated or censored. If the information about the censored samples is not included in the estimation method, as i

Fracture Mechanics of Collagen Fibrils: Influence of Natural Cross-Links

Tendons are important load-bearing structures, which are frequently injured in both sports and work. Type I collagen fibrils are the primary components of tendons and carry most of the mechanical loads experienced by the tissue, however, knowledge of how load is transmitted between and within fibrils is limited. The presence of covalent enzymatic cross-links between collagen molecules is an import

Earwitnesses: the type of voice lineup affects the proportion of correct identifications and the realism in confidence judgments.

According to Tulving and Thomson (1973), similarity in encoding and recall contexts will facilitate recall. We investigated if similarity between the original voice event and the voice lineup helps people to identify the target from a voice lineup and helps improve the realism in participants' confidence judgments of the identification reports. Participants (n = 199) tried to identify a voice hear

Responsiveness of the OARSI-OMERACT osteoarthritis pain and function measures

Objective: To assess the responsiveness of the Intermittent and Constant Osteoarthritis Pain (ICOAP) measure, Hip Disability and Osteoarthritis Outcome Score Physical Function Short Form (HOOS-PS), and the Knee Disability and Osteoarthritis Outcome Score Physical Function Short Form (KOOS-PS) in a pharmacological trial. Methods: Data were obtained from a randomized double-blind trial comparing nap

Cancer incidence among Iranian immigrants in Sweden and Iranian residents compared to the native Swedish population

Background and goals: Comparing cancer incidence by migrant studies is one of the main approaches to generate hypotheses on the aetiology of cancer. Immigrant studies are most informative when cancer incidence data are available from both the Source and the host country. Methods: The age standardised incidence rate (ASR) and standardised incidence ratio (SIR) of cancers among the Iranian immigrant

Phosphorus and carbon availability regulate structural composition and complexity of AM fungal mycelium.

The regulation of the structural composition and complexity of the mycelium of arbuscular mycorrhizal (AM) fungi is not well understood due to their obligate biotrophic nature. The aim of this study was to investigate the structure of extraradical mycelium at high and low availability of carbon (C) to the roots and phosphorus (P) to the fungus. We used monoxenic cultures of the AM fungus Rhizophag

Tapasin Facilitation of Natural HLA-A and -B Allomorphs Is Strongly Influenced by Peptide Length, Depends on Stability, and Separates Closely Related Allomorphs.

Despite an abundance of peptides inside a cell, only a small fraction is ultimately presented by HLA-I on the cell surface. The presented peptides have HLA-I allomorph-specific motifs and are restricted in length. So far, detailed length studies have been limited to few allomorphs. Peptide-HLA-I (pHLA-I) complexes of different allomorphs are qualitatively and quantitatively influenced by tapasin t

Assessment and analysis of housing accessibility: adapting the environmental component of the housing enabler to United States applications.

The home environment is a primary context for daily activities, especially among older adults and persons with disabilities. Functional and age-related decline can generate problems in relation to certain environmental features, necessitating modifications or other provisions of support. The determination of appropriate home interventions is best served using a person–environment (P–E) fit approac

High-Sensitivity CRP Is an Independent Risk Factor for All Fractures and Vertebral Fractures in Elderly Men: The MrOS Sweden Study

Epidemiological studies have shown low-grade inflammation measured by high-sensitivity C-reactive protein (hs-CRP) to be associated with fracture risk in women. However, it is still unclear whether hs-CRP is also associated with fracture risk in men. We therefore measured serum levels of hs-CRP in 2910 men, mean age 75 years, included in the prospective population-based MrOS Sweden cohort. Study p

Evaluation of Plasma A beta as Predictor of Alzheimer's Disease in Older Individuals Without Dementia: A Population-Based Study

Amyloid-beta (A beta) pathology is a major component in the mechanisms behind Alzheimer's disease (AD). Measurement of A beta(42) in cerebrospinal fluid predicts cognitive decline in patients with mild cognitive impairment and identifies AD in patients with dementia. However, studies on A beta in plasma are contradictory. In this prospective population-based study, plasma A beta(42) and A beta(40)

(3Z,6Z,9Z,12Z,15Z)-pentacosapentaene and (9Z,11E)-tetradecadienyl acetate: sex pheromone of the spruce coneworm Dioryctria abietella (Lepidoptera: Pyralidae)

The spruce coneworm, Dioryctria abietella Denis & Schiffermüller (Lepidoptera: Pyralidae), is a major pest in spruce seed orchards in Europe. Initial work on its pheromone ecology reported significant attraction of males to (9Z,11E)-tetradecadienyl acetate (9Z,11E-14:OAc), but this compound appeared to be a very weak attractant in field trials. In this study, we show that a second female-produ

Fracture characterisation of green glued-polyurethane adhesive bonds in Mode I

Unseasoned (green) spruce timber side boards of size 25 × 120 × 600 mm were flatwise-glued with a one-component PUR adhesive. Glued pairs of boards were then kiln-dried to 12 % moisture content. A special small-scale specimen for testing the fracture properties of the adhesive bond in Mode I was developed in order to evaluate the adhesive bond properties. The complete force versus deformation curv

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

Height is a classic complex trait with common variants in a growing list of genes known to contribute to the phenotype. Using a genecentric genotyping array targeted toward cardiovascular-related loci, comprising 49,320 SNPs across approximately 2000 loci, we evaluated the association of common and uncommon SNPs with adult height in 114,223 individuals from 47 studies and six ethnicities. A total