Rearrangements of chromosome arm 15q are rare but recurrent in conventional lipomas, a tumor type often showing deregulated expression of the HMGA2 gene. In order to assess whether 15q rearrangements could constitute a distinct pathogenetic mechanism, we studied seven cases of conventional lipoma that at G-banding analysis had various rearrangements of 15q12-q21. The breakpoints in 15q were mapped

Using a multitissue, genome-wide gene expression approach, we recently identified a gene module linked to the extent of human atherosclerosis. This atherosclerosis module was enriched with inherited risk for coronary and carotid artery disease (CAD) and overlapped with genes in the transendothelial migration of leukocyte (TEML) pathway. Among the atherosclerosis module genes, the transcription cof

This article examines the cultural and social dynamics of a multi-ethnic medieval town. Taking the lower town of Tallinn as a case study, this paper identifies the major urban ethnic groups living in the town and discusses their co-existence, self-definition, and processes of categorization. It explores ambiguities arising from daily interactions in the shared physical landscape of the town, such

ObjectiveTo study the impact of swollen to tender joint count ratio (STR) and other baseline characteristics on treatment response to a first course of anti-tumor necrosis factor (anti-TNF) therapy in rheumatoid arthritis (RA) patients. MethodsPatients with RA initiating their first course of anti-TNF treatment were included in a structured clinical followup protocol. Based on pragmatic thresholds

The purpose was to illuminate parents' experiences when their children are undergoing an elective colonoscopy performed using polyethylene glycol-based regimes for bowel preparation.

Epigenetic dysregulation has been associated with cognitive decline and Alzheimer's disease. The present study investigated associations between common SNPs in genes regulating DNA methylation and age-related changes in cognitive decline in two independent prospective cohorts of patients suffering from mild cognitive impairment. An association between the rs1187120 SNP in DNMT3A and annual decline

Protecting semi-natural grasslands may through spill-over benefit species richness and abundance of flower-visiting insects in linear habitats, such as uncultivated field boundaries, in agricultural landscapes. However, whether local diversity increases both with decreasing distance from potential source habitats and increasing landscape heterogeneity is poorly known due to a general lack of studi

Extraction and analysis of labile compounds in complex sample matrices, such as plants, is often a big analytical challenge. In this work, the use of a "green and clean" pressurised hot water extraction (PHWE) approach performed in continuous flow mode is explored. Experimental data for extraction and degradation kinetics of selected compounds were utilised to develop a continuous flow extraction

A brief analysis of the American poster to the Swedish vampire film Let the Right One In, relating to genre, audiences and distribution.

Objective. The aim of this study was to investigate how distance to hospital and socioeconomic status (SES) influence the use of secondary health care (SHC) when taking comorbidity into account. Design and setting. A register-based study in Ostergotland County. Subjects. The adult population of Ostergotland County. Main outcome measures. Odds of SHC use in the population and rates of SHC use by pa

The use of compression garments in treating lymphedema following treatment of genital (penis, testes, uterus, cervical) and breast cancer treatment is a well-established practice. Although compression garments are classified in compression classes, little is known about the actual subgarment pressure exerted along the extremity. The aims of this study were to establish an in vitro method for measu

I uppsatsen behandlas domstolars bedömning av orsakssambandet mellan hälso- och sjukvårdspersonalsstraffrättsliga oaktsamhet och patienters skador eller död. Vårdpersonal är inte undantagna det straffansvar som följer av brottsbalken. Det är dock ovanligt att åtal väcks mot personal inom hälso- och sjukvården och det är ännu mer ovanligt med fällande domar i de fall som prövats av domstol. Detta bThe present study examines the court's evaluation of the causal relationship between the criminal negligence of healthcare professionals and the subsequent injury or death of patients. Healthcare professionals are not exempt from criminal liability under the Criminal Code. However, prosecutions of healthcare professionals are uncommon, and convictions in cases tried by the courts are even rare

I Sverige har brottsligheten i kriminella miljöer ökat drastiskt under de senaste åren. En markant ökning av antalet skjutningar och sprängningar har noterats och brottsbekämpande myndigheter har haft ett behov av effektivare verktyg för att förhindra denna brottslighet. Ett sådant verktyg är preventiva tvångsmedel. Användningen av dessa regleras bland annat i preventivlagen (2007:979). AnvändninIn Sweden, crimes committed within criminal networks have increased dramatically in recent years. Shootings and explosions have become more common. Swedish law enforcement authorities have needed more effective tools to prevent these crimes and one such tool is preventive coercive measures. The regulation of preventive coercive measures has expanded in recent years. Since 1 October 2023, these mea

Häktning beskrivs ofta som det mest ingripande tvångsmedlet inom den svenska strafflagstiftningen. Att frihetsberöva en människa bör därför göras med stor omsorg, i synnerhet när den misstänkte är under 18 år. Unga lagöverträdare tillerkänns en särbehandling som gör sig märkbar redan vid inledningsstadiet av ett brott. I takt med en allt mer grov och organiserad brottslig-het blir häktning ett effDetention is often described as the most intrusive coercive measure within the Swedish criminal legislation. Therefore, the deprivation of liberty should be carried out with great care, especially when the suspect is under 18 years of age. Young offenders are treated differently, which becomes apparent already at the initial stage of an offense. As crimes become increasingly more serious and organ

Bakgrund: Ambulanspersonal hanterar ofta känslomässigt utmanande och traumatiska situationer, vilket kan leda till compassion fatigue, en form av emotionell utmattning som påverkar deras empatiska förmåga och välbefinnande. Samtidigt finns compassion satisfaction, den positiva känsla som uppstår när ambulanspersonal upplever tillfredsställelse och mening i sitt arbete. Compassion satisfaction fung

Den 1 december 2023 trädde lagen (2023:560) om granskning av utländska direktinvesteringar (UDI-lagen) i kraft. Syftet med lagen är att skydda svenska skyddsvärda verksamheter från fientliga utländska aktörers infly-tande. Anmälningsskyldigheten är ett av lagens verktyg för detta ändamål. Den ålägger investerare (oavsett nationalitet) en plikt att anmäla sina investe-ringar i förväg, om investerarThe Foreign Direct Investment Act (the FDI Act) went into force on Decem-ber 1, 2023. The purpose of the legislation is to protect Swedish protection-worthy business from hostile foreign investors. A mandatory notification re-quirement is included in the FDI Act as a tool for achieving this purpose. The notification requirement forces investors (regardless of nationality) to report their investmen

Paketeringsförfarandet må ha passerat toppen av sin mediala aktualitet sedan paketeringsutrednings framställan av sitt betänkande. Detta bör inte tas för att innebära att samtliga frågor anknytande till förfarandet och dess utfall är ut-tömda på intressant argumentation och utforskning. I denna uppsats undersöks paketeringsförfarandet i eftermälet av paketerings-utredningens betänkande. I kort syThe procedure of packaging real estate may have passed the peak of its media relevance since the Packaging Inquiry presented its report. This should not be taken to mean that all issues related to the procedure and its outcomes have been exhausted of interesting argumentation and exploration. This essay examines the packaging procedure in the aftermath of the Packag-ing Inquiry's report. In b

Denna uppsats behandlar värderingen av immateriella tillgångar i svenska konkursförfaranden, med fokus på metoder, utmaningar och begränsningar som präglar denna process. Immateriella tillgångar, såsom patent, varumärken, domäner och kundrelationer, har blivit allt viktigare i en modern ekonomi där innovation och teknologiska lösningar utgör centrala konkurrensfördelar. Trots detta saknar immateriThis essay addresses the valuation of intangible assets in Swedish bankruptcy proceedings, focusing on the methods, challenges, and limitations that characterize this process. Intangible assets, such as patents, trademarks, domains, and customer relationships, have become increasingly important in a modern economy where innovation and technological solutions constitute key competitive advantages.

Bakgrund: Ambulanspersonal och akutvårdssjuksköterskor arbetar under pressande förhållanden, där de ofta utsätts för stressfaktorer som dödsfall, våld och traumatiska händelser. Studier visar att en stor del av ambulanspersonalen anser att deras arbete är psykiskt påfrestande, och problem som akut och kronisk stress, sömnsvårigheter och PTSD är vanliga bland dem. Det har blivit tydligt att detta a

Despite Mexico having a poor reputation when it comes to women’s rights domestically, the country adopted a feminist foreign policy in 2020. First introduced by Sweden in 2014, the intent and results of feminist foreign policies have been widely questioned. The aim of this thesis is to investigate the effect of Mexico’s adoption of a feminist foreign policy. To do so, Mexican statements to the Uni