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Background: The neotropical anopheline mosquito Anopheles darlingi is a major malaria vector in the Americas. Studies on mosquito-associated microbiota have shown that symbiotic bacteria play a major role in host biology. Mosquitoes acquire and transmit microorganisms over their life cycle. Specifically, the microbiota of immature forms is largely acquired from their aquatic environment. Therefore
Background: Long-term consequences of posterior cruciate ligament (PCL) injury such as persistent posterior tibial translation and risk of osteoarthritis development are unclear. Additionally, little data is available describing the natural history of structural morphology of the ruptured PCL. The purpose of the study was to determine the long-term outcome after non-operatively treated PCL injury.
This study examines whether the IS 2010 Curriculum Guidelines and IS2020 Competency Model match employer expectations in Sweden. This is done by content analysis of 12 358 IS job advertisements, focusing on occupations, dispositions, technical skills, architecture, and the importance of programming. We find that: 1. The occupation group of ICT System Administration is much more important than in t
Reliably identifying short-lived chemical reaction intermediates is crucial to elucidate reaction mechanisms but becomes particularly challenging when multiple transient species occur simultaneously. Here, we report a femtosecond x-ray emission spectroscopy and scattering study of the aqueous ferricyanide photochemistry, utilizing the combined Fe Kβ main and valence-to-core emission lines. Followi
Background and aim: Neuropathic pain arises as a direct consequence of a lesion or disease affecting the somatosensory system. Pharmacological treatments for neuropathic pain often fail despite following guidelines. Interdisciplinary Pain Rehabilitation Programs (IPRP) are an effective intervention for chronic pain conditions. Little research has investigated whether IPRP can benefit patients with
Background: [18F]PSMA-1007 is a prostate specific membrane antigen (PSMA) ligand for positron emission tomography (PET) imaging of prostate cancer. Current guidelines recommend imaging 90–120 min after injection but strong data about optimal timing is lacking. Our aim was to study whether imaging after 1 h and 2 h leads to a different number of detected lesions, with a specific focus on lesions th
There is a close relationship between the SARS-CoV-2 virus and lipoproteins, in particular high-density lipoprotein (HDL). The severity of the coronavirus disease 2019 (COVID-19) is inversely correlated with HDL plasma levels. It is known that the SARS-CoV-2 spike (S) protein binds the HDL particle, probably depleting it of lipids and altering HDL function. Based on neutron reflectometry (NR) and
Oxidation of NH3/n-heptane mixtures at pressures up to 100 atm and temperatures of 400–900 K was characterized experimentally in a laminar flow reactor and a jet-stirred reactor. A detailed chemical kinetic model was developed, updating the hydrogen and amine subsets and introducing a subset for the chemical coupling with emphasis on the NH2+n-heptane reaction. The kinetic model provided a good pr
Comparisons of transthoracic echocardiography (TTE) and cardiovascular magnetic resonance (CMR) derived left ventricular ejection fraction (LVEF) have been reported in core-lab settings but are limited in the real-world setting. We retrospectively identified outpatients from 4 hospital sites who had clinically indicated quantitative assessment of LVEFTTE and LVEFCMR and evaluated their concordance
There is a long history presuming smell is not expressible in language, but numerous studies in recent years challenge this presupposition. Large smell lexica have been reported around the world thereby showing high lexical codability in this domain. Psycholinguistic studies likewise find smell can be described with relatively high agreement, demonstrating high efficient codability. Often the two
Purpose: Point-of-care imaging with mobile CT scanners offers several advantages, provided that the image quality is satisfactory. Our aim was to compare image quality of a novel mobile CT to stationary scanners for patients in a neurosurgical intensive care unit (ICU). Methods: From November 2020 to April 2021, all patients above 18 years of age examined by a mobile CT scanner at a neurosurgical
L’accord sujet-verbe (SV) en nombre en français parlé (e.g. la fille dit X vs. les filles disent X) est un trait grammatical difficile à apprendre pour les apprenants suédois de français L2 (Bartning & Schlyter 2004). Dans ce domaine, ces apprenants commettent souvent des erreurs du type Les filles *dit X (Ågren 2014). Dans cette étude, nous posons la question de savoir si ces erreurs sont par
Background/Aims: Retinopathy of prematurity (ROP) is currently diagnosed through repeated eye examinations to find the low percentage of infants that fulfil treatment criteria to reduce vision loss. A prediction model for severe ROP requiring treatment that might sensitively and specifically identify infants that develop severe ROP, DIGIROP-Birth, was developed using birth characteristics. DIGIROP
Most parliamentary democracies have seen a rise of populist radical parties during the past decades. Many countries have also experienced severely delayed government formation processes, with caretaker governments in office for extended periods of time. Are these delays related to the rise of radical parties? We argue that the rise of populist radical parties may prolong the bargaining process, du
Tropical forest tree communities are structured by a range of large-scale drivers including elevation, certain high-impact anthropogenic activities (e.g., deforestation), and fires. However, low-impact human activities such as foraging may also be subtly but notably altering the composition of tropical forest tree communities. The study assessed the (i) differences in species diversity, patterns o
The phase gradient autofocus (PGA) is a robust autofocusing approach that can efficiently refocus defocused synthetic aperture radar (SAR) imagery produced by frequency-domain algorithms. However, from a conventional viewpoint, PGA cannot be extended to refocus SAR imagery produced by time-domain algorithms, such as the filtered backprojection (FBP), as the spectrum of the FBP imagery is range amb
This study sets out to gain a better understanding of the workings of ancient polytheism by exploring one of its fundamental modus operandi: the cohabitation of gods in sanctuaries. Cohabitation is broadly understood as the permanent or temporary sharing of sacred precincts, cultic buildings, and sacrificial structures by two or more deities, rendered present through their effigies, or merely pres
The role of microglia in tau accumulation is currently unclear but could provide an important insight into the mechanisms underlying Alzheimer’s disease (AD)1. Here, we measured the microglial marker soluble TREM2 and the disease-associated microglial activation stage 2 markers AXL, MERTK, GAS6, LPL, CST7, SPP1 and CSF1 in nondemented individuals from the Swedish BioFINDER-2 cohort who underwent l
A new plesiosaur partial skeleton, comprising most of the trunk and including axial, limb, and girdle bones, was collected in the lower Sinemurian (Coimbra Formation) of Praia da Concha, near São Pedro de Moel in central west Portugal. The specimen represents a new genus and species, Plesiopharos moelensis gen. et sp. nov. Phylogenetic analysis places this taxon at the base of Plesiosauroidea. Its
Background: Women with Turner syndrome (TS) have an increased risk of aortic dissection. The current recommended cutoff to prevent aortic dissection in TS is an aortic size index (ASI) of ≥2.5 cm/m2. This study estimated which aortic size had the best predictive value for the risk of aortic dissection, and whether adjusting for body size improved risk prediction. Methods: A prospective, observatio
